The Tube Dominance test is a simple behavioral assay to assess social hierarchy and social dominance in rodents. The Tube Dominance Test is commonly employed in laboratory settings to study social behavior and interactions in a controlled environment. It can be used with or without food rewards to incentivize the animals to move through the tube. In the simple version, without rewards, two...

The Cincinnati Maze (9T-maze) is an evolution of the Biel Maze with an increased number of interconnected T-mazes.

It is most commonly used as a water maze to avoid scent issues and is used on rats to study egocentric navigation (memory). In order to avoid any possibility of external cue use, the maze is constructed in IR-transparent Perspex to run the experiment in full darkness and...

The object recognition test is now among the most commonly used behavioral tests for memory studies in rodents. In its simplest design, an animal is presented with two similar objects during the first session and then one of the two objects is replaced by a new object during a second session or is moved to a different location.

This test is based on the spontaneous tendency of rodents...

Measures the force on a rat or mouse paw according to the Randall-Selitto paw-pressure test, it enables rapid and precise screening of analgesic drugs for anti-nociceptive studies, in healthy or inflamed limbs. The device applies a steady increasing force, starting and stopping using the foot pedal. No calibration required. Digital model with force sensors and electronic unit is also...

Measures small changes in volume & oedema (fluid retention) to gauge the inflammatory response such as for anti-inflammatory screening tests.

Hands-free operation. Precision measurements. Detects and displays 0.01 ml changes in rodent paw volume. Easy data transfer and software included.

Measures hypersensitivity to thermal (hot and cold) and/or mechanical stimulation of the orofacial area in rats (mouse adaptor available). For research into a wide range of pain conditions involving the trigeminal nerve.

High throughput with data recorded from up to 16 cages with ORO-Software. Real time data display. Non-invasive, respectful test. Comprehensive metrics and easy data...

The hot cold plate test has been the gold standard test for thermal pain tests in rodents for decades. Through the years the devices have been improving and the techniques have become more sophisticated, adding to constant temperature methods also other ones.

The Ugo Basile Hot/Cold plate test includes all the latest technologies necessary to run constant temperature, linear ramping...

The Thermal Place Preference test can be considered an evolution of the Hot/Cold plate test and it allows monitoring of temperature preferences by measuring the time spent in two compartments set at two different temperatures.

This two temperature nociception test can be used in a mouse or rat and is composed of a standard hot/cold plate and of an hot plate, connected by a corridor. It...

Provides simple, reliable and precise calibration for Ugo Basile Plantar Test & Tail Flick and other infrared (I.R.) analgesia meters.

In the late ‘80s Dr. Hargreaves invented a method to assess thermal pain sensation in unrestrained rodents by stimulating the single hind paw and thus allowing for unilateral/contralateral experiments. Ugo Basile made a science-grade instrument to perform this stimulation and automatically measure response, it became a gold-standard with more than 2,600 publications.

A thermal...

Used to measure the paw withdrawal reflex when the mouse or rat paw is unexpectedly touched. For evaluating mechanical allodynia and cutaneous sensation levels. Popular non-invasive technique.

Set of 20 monofilaments based on the Semmes Weinstein monofilament set. An ascending series of increasingly stiff filaments (from 0.008 to 300 grams). Features retractable head to protect the...

The LUX Infrared (IR) illuminator allows for illumination from below of all the Ugo Basile IR mazes, which are made of an IR translucent plastic. This has the double advantage of: making experiments in the darkness easy and enhancing the contrast for better detection, no matter the animal color

The lux is available in 3 sizes, it guarantees a uniform illumination and incorporates IR...

Touch sensitivity in unrestrained animals is traditionally tested with Von Frey filaments, which is a tedious and experimenter-dependent assay.

The Electronic Von Frey system solves the multiple measurement (i.e. multiple filaments) issue and the experimenter bias by using a hand-held force sensor with a rigid metal. The scientist gradually increases the force applied to the animal...

Touch sensitivity is traditionally tested with Von Frey filaments, which is a tedious and experimenter-dependent assay.

The Dynamic Plantar Aesthesiometer is a unique system, which fully automates the amount of force applied by an electromagnetic, silent motor exerting from 0 to 100 grams at a rate adjustable from 0 to 50 seconds.

When the animal responds, by withdrawing its...

Accurately measures the nociceptive threshold to infrared heat stimulus on the rat or mouse tail. Used for rapid screening of analgesic drugs by measuring reaction time to heat, even in anesthetized animals, crucial for repeated tests, thanks to the reflexive nature of the tail flick response.

Adjustable I.R. intensity, bright touch-screen display with intuitive controls. Comfortable...

Measures the weight distribution difference between an injured and unaffected hind paw of a mouse or rat. For the assessment of spontaneous pain in osteoarthritis, bone cancer, nerve injury and post-operative pain studies. Automatic operation reduces operator bias, optimizes repeatability and saves time. Easy to set up. Data visualization to monitor trends. Fast and easy cleaning...

Climbing behavior can be of interest for the most diverse applications.

The Ugo Basile automated system replicates its first manual application in the Pain field, for measuring Pain-Depressed behavior. It showed that, while mild analgesics block pain-depressed climbing, strong analgesics fail to alleviate depression of climbing (Santos et al. 2023, “Climbing behavior by mice as an...

A set up for testing active avoidance (also called automatic reflex conditioner or shuttle box), i.e. learning to predict the occurrence of an aversive event, based on the presentation of a specific stimulus. Enables performance of a wide range of avoidance experiments using a flexible schedule. Precise detection of avoiding aversive event. Manage up to 4 cages with one controller.

The cubicle is a sound-attenuating chamber that isolates small animal subjects from distracting ambient light, sound and activity. For behavioral studies including operant behavior (Skinner), self-administration, etc.

High-level soundproof efficacy, noiseless fan, control box. Extra fixtures (speaker and video camera holder) for fear conditioning studies. Available in standard, large...

A classic way to assess short or long-term memory in small laboratory animals (rodents) using a fear-motivated avoidance task. Used routinely in animal model studies of aging and Alzheimer-type dementia, including the search for new therapeutic drugs.

An efficient, reliable instrument for use with mice (or small rats). A silent, automated sliding door divides compartments. Precision...

Passive Avoidance Test is used to assess memory function based on the association formed between a specific environmental context, which the animal learns to avoid and an aversive stimulus – represented by a mild foot shock.

Efficient and reliable. Silent, automated sliding door divides the dark and light compartments. Systems for mice or rats. Manage up to 4 cages with one...

When rodents are exposed to inescapable and unpredictable stress, such as forced swim or inescapable foot shock, they often develop deficits in memory and learning tasks (e.g. Active Avoidance) and they often show analgesic reactions (S.I.A. Stress-Induced Analgesia).

The Ugo Basile Set-Up for Learned Helplessness is based on a sophisticated generator of unpredictable random shocks...

Best choice for thermal preference phenotyping

Now available for tethered and non-tethered Mice

The state-of-the-art thermal preference assay designed with a circular shape. Fully automatic, up to 36 scientific publications

The TGR can clearly discriminates temperature-dependent phenotypes or temperature dependent drug...

A 2-compartment box that offers visual and tactile differences. For evaluating the abuse potential of substances and the motivational effects of drugs in mice or rats.

Interchangeable floors, optimized for use with video-tracking software or visual scoring, thanks to the grey, high-contrast color and non-smooth, non-reflective paint.

The Porsolt Forced Swim Test (FST), or Porsolt Swim Test (PST), also known as the Behavioral Despair Test, is centered on the way rodents respond to their threat of drowning. This has been correlated to their mood, or, more precisely to their level of depression, with non-depressed animals that swim longer than depressed animals, who, instead, give up and float immobile.

By...

The flexible rodent Lickometer - Vogel Test can operate as both a simple software-based lickometer as well as a system for drinking-conflict experiments (coupled with electric shocks). For assessing anxiety and the anxiolytic effect of drugs.

Rat and mouse models. Easy data collection within the included software for windows. Up to 5 cages can be managed by 1 PC.

Studies natural curiosity and exploration behavior of rodents when confronted with a new environment (head-plunging, or nose-poking stereotype) according to the method devised by Boissier-Simon. For testing effects of psychotropic drugs on exploratory behavior.

The Boards are available with opaque or transparent walls for use with video tracking software. Mouse or rat versions.

Antidepressant drugs and depression animal model genetic screening are commonly conducted by using the Tail Suspension Test (TST). This test is based on the aversive effect of hanging a mouse of rat by the tail, which elicits its struggling moving upwards in an attempt to escape (which is obviously not possible).

The struggling attempt tends to be shorter in duration and translates...

Running wheels provide a convenient method for measuring rodent spontaneous motor activity over long periods of time. Used for research on circadian rhythms, motor function, aging, energy balance, recovering and pain related exercise.

Robust mouse and rat models measure rodent activity across time. Models available with an LCD counter and can also be connected to a Windows PC. Data...

The Ugo Basile Pellet Dispenser works with pellets between 10-20 mg for mice and 22-45 mg for rats. It has an extremely high delivery accuracy thanks to the redundant photobeam check.

An embedded electronic board manages the DC motor and the photodiodes. An ethernet cable connects the Pellet Dispensers to the 8 channel control unit to independently manage up to 8 pellet...

Enables recording of spontaneous locomotor activity in rats and mice (individual or groups) using infrared (I.R.) beams. General activity can be an indicator of drug action, toxic substances, neurological damage, or daily rhythms in activity.

Tracks horizontal and vertical activity (rearing). Easily integrated with video-tracking system to measure XY position. Easy touch-buttons,...

Set-shifting task has proven to be an effective preclinical tool for drug testing and genetic screening, with direct translational valence in healthy humans and patients with schizophrenia.

The Ugo Basile Operon automatizes the Intra-/Extra-dimensional (ID/ED) attentional set-shifting battery of tests offering visual, olfactory and tactile stimulations, all controlled by software and...

The Grip Strength Meter determines the maximum force displayed by an animal in the forelimb, hind-limb or all four limbs, thanks to the full set of accessories included in the Ugo Basile Grip Strength Meter package.

The technique exploits the instinctive resistance of rodents to backward movements and their consequence tendency to grasp (grip) against the pull-back...

An essential instrument to measure current on Ugo Basile devices using electric shock grid, such the Fear Conditioning System, Active an Passive avoidance system.

Give the research the ability to measure the electric shock current not measurable by a common volt-meter. To ensure that the same current is delivered on multiple electric shock grids, while performing multiple test in...

Measures endurance, distance and speed. For studying behavioral, physiological, biochemical, and molecular responses to both acute exercise stress and chronic exercise training.

Original product by Ugo Basile is adaptable for use by rats or mice. Easy set up and control using touch screen. Automatic measurement of endurance, distance and speed. Shock grid for aversive stimulus (if...

Enlargers for Mouse and Rat RotaRod are available to add multiple parameters to change the complexity of the experiment. Enlargers add-on for RotaRod come with grooves to increase the diameter of the rod or in smooth rubber to increase the diameter of the rod and change the surface from a grooved one to a smooth one. All the types of enlargers can be easily added to the rotating drum thanks to...

The Operant Fear Conditioning Cage couples a classic skinner box with sound and light cues for complex experiments, as well as standard operant tests and fear conditioning protocols.

The complex wheel add-on for mouse and rat RotaRod introduces an additional complexity element for the animal to be tested. Thanks to the asymmetrical and adjustable bars it increases the test sensitivity and add a higher involvement of motor cortex and hippocampus, as compared to the classic rotarod test.

The Ugo Basile RotaRod is the 1st and original, invented after the Dunham and...

The Ugo Basile Fear Conditioning system is composed of:

• Isolation cubicle, including all electronics, fan, IR/VIS lights, camera (up to 16 cubicles can be connected to 1 PC)
• The animal cage is available in different dimensions for rats and mice, plus the observational learning version to allow two animals to see each other. The standard...

New Startle/PPI System, with enhanced performance, ease of use and convertible into Fear Conditioning in 1’

The new 2025 version of Startle/PPI system has been recently upgraded to provide enhanced precision, flexibility, and ease of use.

The main improvements include:

• Easy Platform Calibration: The sensitivity and offset of the...

The RotaRod is a simple test to assess motor function and coordination in rodents. Motor coordination or fatigue can be evaluated by measuring the time the animal stays on a rotating rod before falling. The Rod can rotate at constant, accelerating, rocking (back and forth) or through complex acceleration/deceleration ramps, thanks to the included PC software XPad.

The Ugo Basile...

An essential optional tool for Your TGR experiments. This cabinet is made to efficiently control the inside temperature from 0° up to 70° and can hold up to two TGR apparatus.

In TGR experiments temperature is critical; to perform the test (which normally takes 1 hour) You need to ensure the TGR apparatus is placed into an environment having the average temperature between the two...

An essential optional tool for Your TGR experiments. This cabinet is made to efficiently control the inside temperature from 0° up to 70° and can hold up to two TGR apparatus.

In TGR experiments temperature is critical; to perform the test (which normally takes 1 hour) You need to ensure the TGR apparatus is placed into an environment having the average temperature between the two...

A simple Y-shape design provides rodents with a single choice point with only two alternatives. Widely used to measure preference and spatial memory and learning tasks in laboratory animals.

High quality maze with rat and mouse versions. Provides optimal results with video tracking software (high contrast, non reflective). Surface texture selected for rodent comfort. Easy to set up,...

A simple Y-shape design provides rodents with a single choice point with only two alternatives. Widely used to measure preference and spatial memory and learning tasks in laboratory animals.

High quality maze with rat and mouse versions. Provides optimal results with video tracking software (high contrast, non reflective). Surface texture selected for rodent comfort. Easy to set up,...

A test for spatial learning and long-term memory in rodents. For research into neurocognitive disorders and treatments, aging, drug-abuse, neural systems, neurotransmitters and brain development.

High quality, strong and low weight. Embedded wheels for easy movement. Easy to drain and clean. Add optional Atlantis System to extend test capabilities. Different colors available.

A test for spatial learning and long-term memory in rodents. For research into neurocognitive disorders and treatments, aging, drug-abuse, neural systems, neurotransmitters and brain development.

High quality, strong and low weight. Embedded wheels for easy movement. Easy to drain and clean. Add optional Atlantis System to extend test capabilities. Different colors available.

A test for spatial learning and long-term memory in rodents. For research into neurocognitive disorders and treatments, aging, drug-abuse, neural systems, neurotransmitters and brain development.

High quality, strong and low weight. Embedded wheels for easy movement. Easy to drain and clean. Add optional Atlantis System to extend test capabilities. Different colors available.

A test for spatial learning and long-term memory in rodents. For research into neurocognitive disorders and treatments, aging, drug-abuse, neural systems, neurotransmitters and brain development.

High quality, strong and low weight. Embedded wheels for easy movement. Easy to drain and clean. Add optional Atlantis System to extend test capabilities. Different colors available.

New Startle/PPI System, with enhanced performance, ease of use and convertible into Fear Conditioning in 1’

The new 2025 version of Startle/PPI system has been recently upgraded to provide enhanced precision, flexibility, and ease of use.

The main improvements include:

• Easy Platform Calibration: The sensitivity and offset of the...

New Startle/PPI System, with enhanced performance, ease of use and convertible into Fear Conditioning in 1’

The new 2025 version of Startle/PPI system has been recently upgraded to provide enhanced precision, flexibility, and ease of use.

The main improvements include:

• Easy Platform Calibration: The sensitivity and offset of the...

The Thermal Place Preference test can be considered an evolution of the Hot/Cold plate test and it allows monitoring of temperature preferences by measuring the time spent in two compartments set at two different temperatures.

This two temperature nociception test can be used in a mouse or rat and is composed of a standard hot/cold plate and of an hot plate, connected by a corridor. It...

The Thermal Place Preference test can be considered an evolution of the Hot/Cold plate test and it allows monitoring of temperature preferences by measuring the time spent in two compartments set at two different temperatures.

This two temperature nociception test can be used in a mouse or rat and is composed of a standard hot/cold plate and of an hot plate, connected by a corridor. It...

Antidepressant drugs and depression animal model genetic screening are commonly conducted by using the Tail Suspension Test (TST). This test is based on the aversive effect of hanging a mouse of rat by the tail, which elicits its struggling moving upwards in an attempt to escape (which is obviously not possible).

The struggling attempt tends to be shorter in duration and translates...

Widely used to measure preference and spatial memory and learning tasks in laboratory animals. The simple T-shape design provides a single choice point with only two alternatives. Especially for CNS disorder studies.

High quality maze with rat and mouse versions. Provides optimal results with video tracking software (high contrast, non reflective). Surface texture selected for rodent...

Widely used to measure preference and spatial memory and learning tasks in laboratory animals. The simple T-shape design provides a single choice point with only two alternatives. Especially for CNS disorder studies.

High quality maze with rat and mouse versions. Provides optimal results with video tracking software (high contrast, non reflective). Surface texture selected for rodent...

Widely used to measure preference and spatial memory and learning tasks in laboratory animals. The simple T-shape design provides a single choice point with only two alternatives. Especially for CNS disorder studies.

High quality maze with rat and mouse versions. Provides optimal results with video tracking software (high contrast, non reflective). Surface texture selected for rodent...

Provides and easy to use means of immobilizing an animal for surgery or procedures such as imaging. Gas Anesthesia (compared to injections) is a very quick way to induce total unconsciousness and also assists fast recovery.

High quality compact, modular and virtually unbreakable system. Reliable and precise delivery of the anesthetic gas to animals. Expandable system providing...