Measures small changes in volume & oedema (fluid retention) to gauge the inflammatory response such as for anti-inflammatory screening tests.
Hands-free operation. Precision measurements. Detects and displays 0.01 ml changes in rodent paw volume. Easy data transfer and software included.
|
Feature |
Benefits |
|---|---|
| Touch screen display | Easy to operate, easily result data viewing |
| Auto-measure function | Easy operation and better measuring accuracy and repeatability |
| USB pen drive | For fast measured data retrieving and experiment data loading |
| Web based LAN connection | Remote data retrieving and experiment data loading |
| Foot-Pedal to freeze the reading | Hand-free operation |
| More than 1000 citations since 1960s | Most applications can be found in bibliography for reference |
| Interchangeable water cells | Same instrument for mice and rats (four different dimensions) |
|
Operation | |
|---|---|
| Power Requirement | Universal input 85-264 VAC, 50-60Hz, 15 W max |
| Data Read-out | Multifunction graphic display |
| Display | 4.3” multifunction color touch-screen display |
| Data Format | 4 digits 2 integers, 2 decimals (e.g.:23.89 ml) |
|
Physical | |
| Weight | 3,5 Kg |
| Shipping Weight | 6.5 Kg |
| Shipping Dimension | 36x55x45 cm |
|
Warranty | |
| Warranty | Plethysmometer is covered by a 12-month warranty + 12 after product registration |
| UB Care | Additional UB-Care can be added for other 12 or 24 months |
The Plethysmometer is an instrument designed to measure very small changes in volume via water displacement measured by a special very precise in house made transducer.
The availability of different (4) paw measurement tubes makes the device adaptable to many different paw dimensions.
In the 60s, Ugo Basile developed the first original device, designed specifically to measure paw swelling in rodents, since then, thousands of scientists have relied on our Plethysmometer to conduct their research on inflammation, publishing almost 3.000 scientific papers!
The instrument is typically used to precisely measure the experimentally induced inflammation of the paw in rodents and its changes due to administration of pharmacological substances potentially active on inflammation.
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37240 Plethysmometer Standard Package (What's in the box) | |
|---|---|
| 37240-210 | Plethysmometer cell stand |
| 37240-154 | Water Tank |
| 37240-001 | Plethysmometer electronic unit |
| 37252 | Standard water cell with Mouse paw tube (diam. 13 mm) and Rat paw tube (diam. 18 mm) with Water level transducer |
| 7155 | Set of Calibration Probes (0.1, 0.2, 0.5, 1, 2, 4 ml) |
| 7160 | Wetting Compound, 100ml bottle |
| M-TF 050-F | 2 mt. of Polyurethane tube for connection: cell to water tank & cell to drain |
| 7168 | Cell Simulator for end-user troubleshooting |
| E-AU 101 | USB Pen Drive including instruction manual (with CE certification), and X-Pad software |
| 37215-303 | Pedal Switch |
|
37240-25 Plethysmometer with special water cell with Rat paw tube (25 mm) (What's in the box) | |
| 37240-210 | Plethysmometer cell stand |
| 37240-154 | Water Tank |
| 37240-001 | Plethysmometer electronic unit |
| 37257 | Special water cell with Rat paw tube (diam. 25 mm) with Water level transducer |
| 7155 | Set of Calibration Probes (0.1, 0.2, 0.5, 1, 2, 4 ml) |
| 7160 | Wetting Compound, 100ml bottle |
| M-TF 050-F | 2 mt. of Polyurethane tube for connection: cell to water tank & cell to drain |
| 7168 | Cell Simulator for end-user troubleshooting |
| E-AU 101 | USB Pen Drive including instruction manual (with CE certification), and X-Pad software |
| 37215-303 | Pedal Switch |
|
37240-35 Plethysmometer with special water cell with Rat paw tube (35 mm) (What's in the box) | |
| 37240-210 | Plethysmometer cell stand |
| 37240-154 | Water Tank |
| 37240-001 | Plethysmometer electronic unit |
| 37259 | Special water cell with Rat paw tube (diam. 35 mm) with Water level transducer |
| 7155 | Set of Calibration Probes (0.1, 0.2, 0.5, 1, 2, 4 ml) |
| 7160 | Wetting Compound, 100ml bottle |
| M-TF 050-F | 2 mt. of Polyurethane tube for connection: cell to water tank & cell to drain |
| 7168 | Cell Simulator for end-user troubleshooting |
| E-AU 101 | USB Pen Drive including instruction manual (with CE certification), and X-Pad software |
| 37215-303 | Pedal Switch |
|
Other Avaible Water Cells And Accessories | |
| 37252 | Standard water cell with Mouse paw tube (diam. 13 mm) and Rat paw tube (diam. 18 mm) with water level transducer |
| 37252-S | Standard water cell with Mouse paw tube (diam. 13 mm) and Rat paw tube (diam. 18 mm) without water level transducer |
| 37257 | Special water cell with Rat paw tube (diam. 25 mm) with water level transducer |
| 37257-S | Special water cell with Rat paw tube (diam. 25 mm) without water level transducer |
| 37259 | Special water cell with Rat paw tube (diam. 35 mm) with water level transducer |
| 37259-S | Special water cell with Rat paw tube (diam. 35 mm) without water level transducer |
| 7182 | 18 mm Displacement Tube for the rat paw |
| 7186 | 13 mm Displacement Tube for the mouse paw |
| 7187 | 25 mm Displacement Tube for the rat paw |
| 7189 | 35 mm Displacement Tube for the rat paw |
| 7153-L | Water level transducer |
| Optional Warranty | |
| 37240-UBC12 | UB Care 12 Additional hardware warranty extension 12 months for Plethysmometer (Valid for SKU 37240) |
| 37240-UBC24 | UB Care 24 Additional hardware warranty extension 24 months for Plethysmometer (Valid for SKU 37240) |
| 37240-25-UBC12 | UB Care 12 Additional hardware warranty extension 12 months for Plethysmometer (Valid for SKU 37240-25) |
| 37240-25-UBC24 | UB Care 24 Additional hardware warranty extension 24 months for Plethysmometer (Valid for SKU 37240-25) |
| 37240-35-UBC12 | UB Care 12 Additional hardware warranty extension 12 months for Plethysmometer (Valid for SKU 37240-35) |
| 37240-35-UBC24 | UB Care 24 Additional hardware warranty extension 24 months for Plethysmometer (Valid for SKU 37240-35) |
A. M. Ajayi, C. B. Ola, M. B. Ezeagu, P. A. Adeleke, K. A. John, M. O. Ologe, B. Ben-Azu, S. Umukoro, 2023, “Chemical characterization, anti-nociceptive and anti-inflammatory activities of Plukenetia conophora seed oil in experimental rodent models”, Journal of Ethnopharmacology
D. Impellizzeri, D. Maftei, C. Severini, R.Miele, G. Balboni, R. Siracusa, M. Cordaro, R. Di Paola, S. Cuzzocrea, R. Lattanzi, 2023, “Blocking prokineticin receptors attenuates synovitis and joint destruction in collagen-induced arthritis”, Journal of Molecular Medicine
O. O. Ariyo, A. M. Ajayi, B. Ben-Azu, A. O. Aderibigbe, 2022, “Morus mesozygia leaf extract ameliorates behavioral deficits, oxidative stress and inflammation in Complete Freund’s adjuvant-induced arthritis in rats”, Journal of Ethnopharmacology
A. Bucan, A. Wiinholt, F. Dalaei, O. Gerke, C. Ronn Hansen, J. Ahm Sorensen, 2022, “Microcomputed tomography versus plethysmometer and electronic caliper in the measurements of lymphedema in the hindlimb of mice”, Scientific Reports
Y. Fotio, O. Sasso, R. Ciccocioppo, D. Piomelli, 2021, “Antinociceptive Profile of ARN19702, (2-*thylsulfonylpheny*)-[(2S)-4-(6-fluor*-1,3-*enzothiazo*-2-yl)-2-*ethylpiperazi*-1-yl]*ethanon*, a Novel Orally Active N-*cylethanolamin* Aci* Amidas* Inhibitor, in Animal Models”, Journal of Pharmacology and Experimental Therapeutics
T. Keränen, T. Hömmö, M. Hämäläinen, E. Moilanen, R. Korhonen, 2026 “Anti-Inflammatory Effects of β2-Receptor Agonists *albutamo* and *erbutalin* Are Mediated by MKP-1”, PLoS ONE
A. Horvat, v. Tékus, M. Boros, G. Pozsgai, B. Potz, E. Borbély, J. Szolcsanyi, E. Pinter, Z. Helyes, 2016, “Transient Receptor Potential Ankyrin 1 (TRPA1) Re-ceptor is Involved in Chronic Arthritis: in Vivo Study Using TRPA1-Deficient Mice”, Arthritis research & therapy
F. T. Bonezzi, O. Sasso, S. Pontis, N. Realini, E. Romeo, S. Ponzano, A. Nuzzi, A. Fiasella, F. Bertozzi and D. Piomelli, 2016, “An Important role for N-*cylethanolamin* Aci* Amidas* in the Complete Freund’s Adjuvant Rat Model of Arthritis”, Journal of Pharmacology and Experimental Therapeutics
T. Iannitti, A. Graham, S. Dolan, 2015, “Adiponecti*-Mediated Analgesia and Anti-Inflammatory Effects in Rat” PLoS ONE
In addition to the one-year Regular Warranty and in addition to the one-year product registration extended warranty, Ugo Basile offers an Optional Extended Warranty that extends the warranty period for the product for additional one or two years called “UB Care12”/“UB Care24”. Customers may purchase the “UB Care” at the maximum of 3 months after buying. For more detailed information, please contact your local representatives.
Thermal Conditioned Cabinet is an essential accessory for your TGR setup. It ensures optimal and stable environmental temperature from 0° up to 70° C (32° up to 158°F), improving test reliability and operator comfort. It holds up to two TGR units and provides insulation from light and noise, with built-in air suction and full connectivity to ANY-maze.
Thermal Conditioned Cabinet is an essential accessory for your TGR setup. It ensures optimal and stable environmental temperature from 0° up to 70° C (32° up to 158°F), improving test reliability and operator comfort. It holds up to two TGR units and provides insulation from light and noise, with built-in air suction and full connectivity to ANY-maze.
