In the late ‘80s Dr. Hargreaves invented a method to assess thermal pain sensation in unrestrained rodents by stimulating the single hind paw and thus allowing for unilateral/contralateral experiments. Ugo Basile made a science-grade instrument to perform this stimulation and automatically measure response, it became a gold-standard with more than 2,000 publications in 2022.

A thermal...

Touch sensitivity is traditionally tested with Von Frey filaments, which is a tedious and experimenter-dependent assay.

The Dynamic Plantar Aesthesiometer is a unique system, which fully automates the amount of force applied by an electromagnetic, silent motor exerting from 0 to 100 grams at a rate adjustable from 0 to 50 seconds.

When the animal responds, by withdrawing its...

Records and analyses thermal preference phenotyping in mice, according to Zimmermann's method. For neuropathic pain studies, temperature sensitivity and insensitivity assessment, always with the animal freely moving and with no user’s intervention.

Novel circular design. Addresses limitations associated with classic devices. Cost effective. Reproducible data.

Creates an opportunity to study attentional set shifting (a measure of cognitive flexibility and executive functions), by testing the ability of rodents to adapt to constantly changing rules. Especially for translational research in psychiatric medicine.

Touch sensitivity in unrestrained animals is traditionally tested with Von Frey filaments, which is a tedious and experimenter-dependent assay.

The Electronic Von Frey system solves the multiple measurement (i.e. multiple filaments) issue and the experimenter bias by using a hand-held force sensor with a rigid metal. The scientist gradually increases the force applied to the animal...

Measures endurance, distance and speed. For studying behavioral, physiological, biochemical, and molecular responses to both acute exercise stress and chronic exercise training.

Original product by Ugo Basile is adaptable for use by rats or mice. Easy set up and control using touch screen. Automatic measurement of endurance, distance and speed. Shock grid for aversive stimulus (if...

Versatile, automated modular device empowers researchers to assemble a custom configuration perfectly suited to spatial learning and spatial memory studies in rats or mice.

The same modular device can be transformed into automated radial, Y, T and Delta mazes by simply rearranging the arms.

Surface texture is selected for best rodent comfort as well as optimal results with...

It assesses motor coordination using natural fear of falling response as motivation. Especially for Parkinson’s, Amyotrophic Lateral Sclerosis (ALS) and other diseases. Simple touch-screen for experiment control and data display.

Simple touch-screen for experiment control and data display. Customizable, uploadable protocols (speed, acceleration, multi-step ramps) for efficiency and...

Fear conditioning is one of the most common methods to measure memory in rodents. It exploits the Pavlovian association between an unpleasant unconditioned stimulus (shock) to a conditioned neutral stimulus (sound cue). The reaction of rodents, as predated animals, is to freeze (stay immobile) when exposed to fearful situations, such as a shock.

Once the association has happened and...

Automatic detection of the startle reflex (pre-pulse inhibition PPI) in mice. Particularly for research into psychiatric disorders, drug use and more.

Customizable, complete set up, ready to go. Includes controller, Startle Link-Box, Isolation Cubicles, Stimulating/Recording Platform.

Measures the weight distribution difference between an injured and unaffected hind paw of a mouse or rat. For the assessment of spontaneous pain in osteoarthritis, bone cancer, nerve injury and post-operative pain studies. Automatic operation reduces operator bias, optimizes repeatability and saves time. Easy to set up. Data visualization to monitor trends. Fast and easy cleaning...

Measures hypersensitivity to thermal (hot and cold) and/or mechanical stimulation of the orofacial area in rats (mouse adaptor available). For research into a wide range of pain conditions involving the trigeminal nerve.

High throughput with data recorded from up to 16 cages with ORO-Software. Real time data display. Non-invasive, respectful test. Comprehensive metrics and easy data...

Identifies temperature sensitivity and nociceptive pain thresholds. For pathophysiological exploration of animal pain models and pharmacological assessment of analgesic drugs. Often called the Two-Temperature Choice Test.

Easy touch screen controls for setting up and monitoring tests. Fast data portability. Fixed or ramp temperatures for dynamic experiments.

This software enables researchers to study behavior in a more reliable and consistent way and over longer time periods than if they were using direct observation or manual recording.

Highly advanced, comprehensive video-tracking system. The software couples an unrivalled depth of features with a simple, familiar design, to provide automated testing in virtually any behavioral...

Measures small changes in volume & oedema (fluid retention) to gauge the inflammatory response such as for anti-inflammatory screening tests.

Hands-free operation. Precision measurements. Detects and displays 0.01 ml changes in rodent paw volume. Easy data transfer and software included.

Accurately measures the nociceptive threshold to infrared heat stimulus on the rat or mouse tail. Used for rapid screening of analgesic drugs by measuring reaction time to heat, even in anesthetized animals, crucial for repeated tests, thanks to the reflexive nature of the tail flick response.

Adjustable I.R. intensity, bright touch-screen display with intuitive controls. Comfortable...

A positive pressure pump (according to Starling’s Ventilator method) for small animals. Assists with breathing during anesthesia and surgery or when an animal has an injury or illness that requires respiratory support.

A set up for testing active avoidance (also called automatic reflex conditioner or shuttle box), i.e. learning to predict the occurrence of an aversive event, based on the presentation of a specific stimulus. Enables performance of a wide range of avoidance experiments using a flexible schedule. Precise detection of avoiding aversive event. Manage up to 4 cages with one controller.

A positive pressure pump (according to Starling's Ventilator method) for mice. Assists with breathing during anesthesia and surgery or when an animal has an injury or illness that requires respiratory support.

Highly accurate, rate displayed digitally, quiet, durable, high quality, long lifetime. Up to 300 strokes/min. Optimizes oxygenation by minimizing dead space. Range of...

A positive pressure pump (according to Starling's Ventilator method) for cats, rabbits and small animals of similar size. Assists with breathing during anesthesia and surgery or when an animal has an injury or illness that requires respiratory support.

Highly accurate rate displayed digitally, choice of cylinder/piston assemblies (50, 100 ml), quiet, robust, high quality, and long...

Enables recording of spontaneous locomotor activity in rats and mice (individual or groups) using infrared (I.R.) beams. General activity can be an indicator of drug action, toxic substances, neurological damage, or daily rhythms in activity.

Tracks horizontal and vertical activity (rearing). Easily integrated with video-tracking system to measure XY position. Easy touch-buttons,...

A powerful complement to any stimulator. Delivers pulses for up to four preparations simultaneously. Adjustable polarity and intensity for each channel.

The cubicle is a sound-attenuating chamber that isolates small animal subjects from distracting ambient light, sound and activity. For behavioral studies including operant behavior (Skinner), self-administration, etc.

High-level soundproof efficacy, noiseless fan, control box. Extra fixtures (speaker and video camera holder) for fear conditioning studies. Available in standard, large...

A valuable tool to study social behavior in rodents. It is especially useful for research on autism disease, parental behavior, sociability, dominance and social memory (social novelty). High quality mouse and rat grids are easy to use and clean. The specific grey base provides unsurpassed contrast for the best video-tracking outcome. Non-smooth surface texture for best rodent comfort and...

A classic way to assess short or long-term memory in small laboratory animals (rodents) using a fear-motivated avoidance task. Used routinely in animal model studies of aging and Alzheimer-type dementia, including the search for new therapeutic drugs.

An efficient, reliable instrument for use with mice (or small rats). A silent, automated sliding door divides compartments. Precision...

Provides and easy to use means of immobilizing an animal for surgery or procedures such as imaging. Gas Anesthesia (compared to injections) is a very quick way to induce total unconsciousness and also assists fast recovery.

High quality compact, modular and virtually unbreakable system. Reliable and precise delivery of the anesthetic gas to animals. Expandable system providing...

Passive Avoidance Test is used to assess memory function based on the association formed between a specific environmental context, which the animal learns to avoid and an aversive stimulus – represented by a mild foot shock.

Efficient and reliable. Silent, automated sliding door divides the dark and light compartments. Systems for mice or rats. Manage up to 4 cages with one...

Based on where a mouse with free movement spends its time in a central arena area with stimulus animals (familiar/unfamiliar/dominant/different gender) positioned in chambers on the outer edge. For research into impairments in social skills that are central to mental disease and developing tools for their assessment in mouse models as well as smell related behavior (anosmia).

High...

Designed for inducing convulsions in research mice and rats for epilepsy studies and many more e.g., neurochemical and neuropharmacological research such as evaluating the depressant or stimulating action of drugs on the CNS.

Reproducible results. Parameters have been selected as the most suitable range for mice or rats. Flexibility to extend your experiments by adding other...