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Animal
Mouse, Rat

Dynamic Plantar Aesthesiometer - For Mechanical Stimulation

Product Code:37550

Automates the assessment of “touch sensitivity” on the plantar surface of rats or mice. For assessment of hypersensitivity and allodynia for analgesia, nociceptive, neuropathic and postsurgical studies.

Unique automation features save significant time for the researcher.

Model
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Background

  • The automated Dynamic Plantar Aesthesiometer (DPA) is a quick, accurate way of delivering mechanical stimulation and measuring a response.
  • Impaired cutaneous sensation is usually first manifested in a loss of light touch detection. Mechanical stimulation is used clinically to diagnose pathologies of hyper- or hypo-aesthesia, brought about by drugs, neural pathology or experimental lesions.

Application & Disease Models

  • Automatically detects and records latency time, and actual force at the time of paw withdrawal reflex. 
  • A movable force actuator is positioned below the plantar surface of the animal. The desired force and force speed (ramp) is applied, as pre-set by the operator.  
  • Increasing force is exerted by rigid Von Frey filament (0.5mm tip) until the animal twitches its paw. 
  • Adjustable touching force and touching pause (to control the stimulus approaching phase).
  • Paw withdrawal detection is automatic. Manual detection is also available (useful if animal motor response is unusual).
  • The device comprises:
    • A movable touch-stimulator unit complete with filament actuator and adjustable angled-mirror
    • A microprocessor controlled electronic unit with touch screen, graphic display, internal memory for data storage, USB key and optional printer
    • Large testing surface (perforated metal platform), laser cut for smooth and precise grid spacing
    • Modular animal enclosure offering from 3 to 12 spaces is convenient for holding rats and mice
  • Supplied with accessories to work with both mice and rats. 
  • Data can be transferred to a computer via the memory stick.
  • TTL outputs for Start/Stop and Detection (Manual/Automatic) as well as TTL Input for external start provide easy interface to external instruments such as DAQs. Analog output is also available.

Impaired cutaneous sensation is usually first manifested in a loss of light touch detection. So “mechanical” stimulation has a long history of effective clinical use to diagnose pa-thologies of hyper- or hypo-aesthesia, brought about by drugs, neural pathology or experimental lesions, etc.

The Dynamic Plantar Aesthesiometer was developed to apply a reproducible light touch to the rodent plantar surface, and quantify the force which causes the animal to react by withdrawing the paw.

 

 

FeatureBenefit
The force is automatically applied Consistency in force application, rate and direction
Maximum force is 100g Works on a broader range of animal models, molecules, diseases
The user only has to press a button The test is quicker and less tedious than VF hairs
Double click of the button triggers manual score Possibility to use manual scoring when animal behaviour is difficult to automatically detect
Force threshold and ramp can be adjusted More parameters to fit with virtually any experimental need
Touch force and touch pause can be adjusted The way the probe approaches the paw can be changed, depending on paw sensitivity
Force automated or manual The force threshold can be scored manually or automatically 
General
Read out and commands

4,3 inches touch-screen (Resistive)

Power Requirements Universal input 100-240 VAC, 50-60 Hz, 30W
Sound Level Negligible
Operating Temperature

10°C to 40°C; 5% to 95% RH (non-condensing)

 

Operation

Force Range

0.1 to 100 grams, in 0.1g steps

Force Increasing Rate (ramp) Adjustable in the interval 0 to 50 seconds, in 1 s steps
Latency Time Display in 0.1s steps

Measurement Mode

Automatic

Start Experiment

By Start button, push buttons or TTL input

Stop experiment

By Stop button, push buttons, cut-off or TTL input

Data input Experiment protocol

Data export

.csv format

TTL/IO Start/Stop, Detection Mode, Force level
Calibration Calibration Weights (5g, 50g, 100g)

 

Physical 

Total Weight 10Kg
Shipping Weight 13Kg
Dimensions (all parts) 135 (w) x 40 (d) x 50 (h) cm (required space on table; all parts)
Packing Dimensions 98x49x47 cm

 

Warranty 

Warranty Dynamic Plantar Aesthesiometer is covered by a 12-month warranty + 12 after product registration.
UB-Care Additional UB-Care can be added for other 12 or 24 months

 

37550 Dynamic Plantar Aesthesiometer
37550-001 Microprocessor controlled electronic unit
37550-002 Touch Stimulator, complete with probe actuator and adjustable angled-mirror
37000-003 Large Platform
37400-327 Supporting column (4)
37000-007 Modular Animal Enclosure
37450-005 Large Framed Perforated Metal Sheet
37450-321

Plastic Case lodging, 2 Filaments (with umbrella), 2 Calibration Weights, 1 hex. Wrench 1.25

E-AU 101 Memory Key, including the user manual and Xpad software
Optional
37450-278 Additional Stimulation Base, complete with perforated metal sheet and animal enclosure
37100 Set of 2 Durham Holders for Orofacial Stimulation 
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