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Animal
Mouse, Rat

Analgesy-Meter

Product Code:37215/37216

Applied force measurements on rat or mouse paw according to the Randall-Selitto paw-pressure test (normal or inflamed). Enables rapid and precise screening of analgesic drugs for anti-nociceptive studies.

Exerts a steadily increasing force with easy start and stop. No calibration required. Design maximises care for animals. Model with digital reading available.

Model
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Background

  • Current model based on over 50 years of expertise and continuous product development.
  • Assesses the force at which the animal feels pain.
  • Typically, the Randall-Selitto method is used as a rapid and sensitive screening of analgesic and anti-inflammatory drugs.
  • Rat/mouse and mouse models available with 3 different force ranges.
  • More than 1000 published papers citing Ugo Basile.

Rapid and precise screening of analgesic drugs

  • Gradually increases pressure on an inflamed animal paw until the animal makes a flinch response.
  • The force can be continuously monitored by a pointer moving along a linear scale.
  • The paw is placed on a small plinth under a cone-shaped pusher with a rounded tip, which does not hurt the animal (other shapes available on request).
  • The 37215 rat/mouse model features 3 force ranges from 0 to 250, 500, 750g.
  • The 37216 mouse model features 3 force ranges from 0 to 125, 250, 375grams.  Also includes a special chisel-shaped pusher (force applicator).
  • No calibration is required. Device is ready for immediate use.
  • Convenient hands-free foot pedal for starting or stopping application of the force.
  • Use of very low friction coefficient (slippery) Teflon prevents paw injury. If hind paw withdrawal threshold is reached, the animal can quickly remove its paw from the plinth.
  • Features a low voltage synchronous motor for low speed and optimum control.
  • A digital add-on is available as an option (force transducer plus display).
  • Upgrade kit for some older UB Analgesy-Meters. Ask for details!

Feature

Benefits 

Same instrument, three different force ranges

Applied force:

37215 from 0 to 250, 500, 750grams (with extra weights)

37216 from 0 to 125, 250, 375grams (with extra weights)

No calibration needed  Simple and reliable
Classic method since the 1960s  More than 1000 papers published!
NEW model with digital reading Upgrade kit for old UB Analgesy-Meters available

 

General
Power Consumption 15W
Operating Temperature 10° to 40° C
Sound Level Negligible

 

Operation

Start / Stop By Pedal Switch
37215 Force Range

From 0 to 250, 500, 750 grams

37216 Force Range From 0 to 125, 250, 375 grams
Force increasing rate Regulated by the Analgesy-Meter configuration
Power Requirements 115V 50/60Hz 230V 50/60Hz
Digital data recording Via optional Analgesy-Meter DAQ 37215-100

 

Physical

Total Weight 3.3 Kg 
Shipping Weight 5.4 Kg approx. 
Dimensions 46 x 16 x 14 cm 
Packing Dimensions 55 x 45 x 36 cm 

 

Warranty

Warranty 367215 / 37216 are covered by a 12-month warranty + 12 after product registration 
UB-Care Additional UB-Care can be added for other 12 or 24 months 

 

The Basile Analgesy-Meter has been designed to perform rapid precise screening of an-algesic drugs on the normal and inflamed rat paw, according to the Randall-Selitto test. The instrument is basically a device which exerts a force increasing at a constant rate (a certain number of grams per second). This force is continuously monitored by a pointer moving along a linear scale.

The force is applied to the animal’s paw, which is placed on a small plinth under a cone-shaped pusher with a rounded tip. The plinth is made of TEFLON, which is biologically inert and has a very low friction coefficient. Thus, if the animal suddenly withdraws its paw, it slips out easily without being injured. The operator depresses a pedal-switch to start the mechanism which exerts the force.

When the rat struggles, the operator releases the pedal and reads off the scale the force at which the animal felt pain.

37215 Analgesy-Meter standard

37215-001 Electronic Unit
37215-002 Paw Transducer
37215-303 Pedal Switch
37215-322 Standard Pusher
37215-323 2 Additional discs Disc M-LM 446
37215-326 Pusher (special chisel-shaped model)
E-AU 101 USB pen drive, including instruction Manual (on USB pen drive)

37216 Analgesy-Meter, low pressure model, suitable for Mouse

37215-001 Electronic Unit
37215-002 Paw Transducer
37215-303 Pedal Switch, complete with cable
37216-323 2 Additional discs Disc M-LM 716-F
37215-326 Pusher (special chisel-shaped model)
E-AU 101 USB pen drive, including instruction Manual (on USB pen drive)

Optional 

37215-327 Mouse Kit, to transform a 37215 into a 37216 (including specific slide, 2 additional weights (50%) and 37215-326 pusher
37215-100 ANALGESY-METER DAQ Upgrade Kit
37215-BUNDLE Analgesy-Meter and Upgrade Kit
37216-BUNDLE Analgesy-Meter and Upgrade Kit, mouse
Back to: Pain and Inflammation