Estimates suggest that 20% of adults suffer from pain globally*. Chronic pain is the most common cause of long-term disabilities. From 1963 Ugo Basile’s devices have had a prominent role in research on pain & inflammation, precious tools for researchers to achieve their experimental goals.
* D. S. Goldberg and S. J. Mcgee, "Pain as a global public health priority"
Measures paw withdrawal latency in unrestrained and unhandled rodents during experiments, in response to an infrared heat stimulus. For studying pain sensitization and thermal pain response recovery.
Automatic detection of paw withdrawal for accuracy.
Automates the assessment of “touch sensitivity” on the plantar surface of rats or mice. For assessment of hypersensitivity and allodynia for analgesia, nociceptive, neuropathic and postsurgical studies.
Unique automation features save significant time for the researcher.
Records and analyses thermal preference phenotyping in mice, according to Zimmermann's method. For neuropathic pain studies, temperature sensitivity and insensitivity assessment, always with the animal freely moving and with no user’s intervention.
Novel circular design. Addresses limitations associated with classic devices. Cost effective. Reproducible data.
Measures mechanical sensitivity thresholds. For the assessment of hypersensitivity and allodynia for analgesic, nociceptive, neuropathic and postsurgical studies. Original design with clear prism for fast localization of stimulation site and reduced animal stress. Digital data display.
Original design with clear prism for fast localization of stimulation site and reduced animal...
Screens thermal hyperalgesia and allodynia, conditions often observed in patients with neuropathic pain or inflammation. Also used for testing analgesic and anti-inflammatory drugs.
Fixed or increasing temperature (RAMP) modes for dynamic experiments. Reaches user-defined temperatures within minutes. Touch screen or X-PAD software for setting up and monitoring tests, including...
Measures the weight distribution difference between an injured and unaffected hind paw of a mouse or rat. For the assessment of spontaneous pain in osteoarthritis, bone cancer, nerve injury and post-operative pain studies. Automatic operation reduces operator bias, optimizes repeatability and saves time. Easy to set up. Data visualization to monitor trends. Fast and easy cleaning...
Measures hypersensitivity to thermal (hot and cold) and/or mechanical stimulation of the orofacial area in rats (mouse adaptor available). For research into a wide range of pain conditions involving the trigeminal nerve.
High throughput with data recorded from up to 16 cages with ORO-Software. Real time data display. Non-invasive, respectful test. Comprehensive metrics and easy data...
Identifies temperature sensitivity and nociceptive pain thresholds. For pathophysiological exploration of animal pain models and pharmacological assessment of analgesic drugs. Often called the Two-Temperature Choice Test.
Easy touch screen controls for setting up and monitoring tests. Fast data portability. Fixed or ramp temperatures for dynamic experiments.
Measures small changes in volume & oedema (fluid retention) to gauge the inflammatory response such as for anti-inflammatory screening tests.
Hands-free operation. Precision measurements. Detects and displays 0.01 ml changes in rodent paw volume. Easy data transfer and software included.
Accurately measures the nociceptive threshold to infrared heat stimulus on the rat or mouse tail. Used for rapid screening of analgesic drugs by measuring reaction time to heat, even in anesthetized animals, crucial for repeated tests, thanks to the reflexive nature of the tail flick response.
Adjustable I.R. intensity, bright touch-screen display with intuitive controls. Comfortable...
Measures the force on a rat or mouse paw according to the Randall-Selitto paw-pressure test, it enables rapid and precise screening of analgesic drugs for anti-nociceptive studies, in healthy or inflamed limbs. The device applies a steady increasing force, starting and stopping using the foot pedal. No calibration required. Digital model with force sensors and electronic unit is also...
Used to measure the paw withdrawal reflex when the mouse or rat paw is unexpectedly touched. For evaluating mechanical allodynia and cutaneous sensation levels. Popular non-invasive technique.
Aesthesio® set of 20 monofilaments based on the Semmes Weinstein monofilament set. An ascending series of increasingly stiff filaments (from 0.008 to 300 grams). Features retractable head to...