Quote list0
Your product list is empty!

Animal
Mouse, Rat

Plantar Test for Thermal Stimulation - Hargreaves Apparatus

Product Code:37570

Measures paw withdrawal latency in unrestrained and unhandled rodents during experiments, in response to an infrared heat stimulus. For studying pain sensitization and thermal pain response recovery.

Automatic detection of paw withdrawal for accuracy.

Model
This product warranty can be extended up to 24 Additional Months.
Discover more HERE!

Background

  • In 1988 K. Hargreaves et al. showed paw withdrawal latency in rodents by thermally stimulating the paws through a transparent glass pane.
  • This method has significantly enhanced pain behavioral testing possibilities.
  • First made available to the scientific community worldwide by Ugo Basile, which started producing the Plantar Test device for mice and rats.
  • The Plantar test is performed through a very simple procedure, during which a rodent hind paw is stimulated with a radiant heat, through a glass pane, using the plantar paw as surface to be irradiated.

 Automatic detection for accuracy

  • Automatic detection of paw withdrawal for accurate data. No mistakes. No visual score needed.
  • User-defined amount and duration of thermal energy.
  • Manual scoring option (useful if animal motor response is unusual or difficult to score).
  • Automatically records the time (latency) paw is withdrawn after the thermal beam is applied to the freely moving animal.
  • Easy touch screen controls for complete management of settings, testing, viewing results and saving data.
  • Supplied as a complete kit for rat or mouse tests containing:
    • A movable I.R. (infrared) generator with embedded paw withdrawal detector
    • A glass pane for placement above the IR source
    • Modular animal enclosures (positioned above the glass pane) for holding up to 6 rats or 12 mice. 
  • Proprietary to our model is a specific filter, cutting off the visible part of the light spectrum, which would disturb the animal on test and provide an unwanted clue.
  • A feedback circuit detects false starts.
  • Easy transfer of data from USB key. Export data as csv format for further analysis in Excel and other programs.

 

 Features

 Benefits

Automatic or manual detection of paw withdrawal  No visual score needed! No mistakes, precise measurement
Touch screen controlling all functions and result viewing Intuitive user interface, new functions, faster use compared to button-based displays
Export Software included Direct export from the electronic unit into USB pen of CSV files
Adjustabl energy intensity 1-99 scale, for ensuring a broad range from light to intense stimulation
Modular Animal Enclosure from 3 to 12 spaces, conveniently designed to restrain up to 12 mice or 6 rats
Optional I.R. Flux Radiometer for calibration to guarantee the same emission in different machines, and after years of use
0.1s sensitivity for paw withdrawal latency  Avoid operator variability and bias through a fully automated system 
 

 

 
General
Command input and readout via 4.3" touch-screen 
Power requirements

Universal input 100-240 VAC, 50-60Hz, 50W

Data Portability via USB flash drive provided
Calibration via appropriate I.R. Radiometer (not included)
Operating Temperature 10° to 40° C, 5% to 95% RH (non-condensing)
Sound Level <54dB

 

Operation

I.R. Intensity Adjustable in the interval 01-99 (in one digit steps)
Latency Time 0.1s steps
Cut off function From 5 to  30 seconds
Measurement mode Manual or Automatic
Start experiment By start icon, push button or TTL input 
Stop experiment By start icon, push button, cut-off, or TTL input
Data export .csv format, from USB key
TTL I/O

Input and output TTL signal

 

Physical

Dimensions 135 (w) x 40 (d) x 50 (h) cm (required space on the table)
Weight 11.0Kg
Packing dimensions 98x49x47cm
Shipping Weight 14Kg approx.

 

Warranty

Warranty 37570 is covered by a 12-month warranty + 12 after product registration
UB-Care Additional UB-Care can be added for other 12 or 24 months
 
 

Determination of acute nociceptive thermal threshold in laboratory animals, has primarily relied upon the tail flick and hot plate methods. Although both methods are used frequently in pharmacological studies, they are not without limitation. 

The Plantar Test represents a remarkable advance in methodology, as it combines the best feature of all other methods of measuring thermal pain sensitivity. Unique to the Plantar Test, the animal is unrestrained and unhandled during experiments. 

In addition, unilateral/contralateral experimental designs are possible by the single stimulation of individual paw (injured or not)

37570 Plantar Test
37570-001 Plantar Test Controller
37570-002 Emitter/Detector Vessel
37000-003 Large Platform
37370-327 4 Supporting column
37000-007 Modular Animal Enclosure
37370-005 Framed Glass Pane
E-WP 008 Main Cable

 

Optional

37300 Heat-Flux I.R. Radiometer
37370-278 Additional Stimulation Base, complete with glass pane and animal enclosure
37100 Set of 2 Durham Holders for Orofacial Stimulation
Back to: Pain and Inflammation