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Animal
Mouse, Rat

Electronic Von Frey - e-VF Handheld

Product Code:38450

Measures mechanical sensitivity thresholds in rodents. For assessment of hypersensitivity and allodynia for analgesia, nociceptive, neuropathic and postsurgical studies.

Original design with clear prism for fast localization of stimulation site and reduced animal stress. Digital data display.

Model
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Background

  • Automatically records the animal response to user-controlled application of force rate.
  • The viewing prism, an original design by Ugo Basile, enables fast localization of the stimulation site on the unrestrained animal.
  • User-defined force rate using a single filament offers greater efficiency compared to manual von Frey (and multiple filaments).
  • Allows stimulation of any part of the body and not only plantar surface also at high forces

Efficient, innovative, reliable

  • The integrated touch stimulator transducer examines and tests the animal skin sensitivity.
  • The rate of application of the force is set by the operator. Software tools help the operator to consistently apply the force at the desired rate.
  • Ergonomic handle reduces operator fatigue
  • Test is completed when the animal releases its paw or the operator presses the foot-pedal (for hands free operation).
  • At test completion, a summary of results is displayed (force and time corresponding to the animal response).
  • The results of several hundred tests may be stored in the e-VF, browsed on the control unit and/or transferred to a PC in Excel (.xls) or text (.txt) format.
  • e-VF Handheld Electronic Von Frey includes:
    • A battery powered electronic control unit with internal memory
    • Touch stimulator with a viewing prism
    • DCA software for signal monitoring, data transfer and analysis.
  • Optional platforms and base options are available for complete set up.

 

FeatureBenefit

Resolution: 0.1g

DCA Software included

Maximum Applicable Force: 1000g

Location of the target via the original prism-design

User-controlled application of force rate

Automatic recording of animal response

* Speaking about force, although the sensor can detect forces from 0 to 1000g, it is reasonable to set the device lower limit to 5g, given by difficulty, even for the most skilled user, to apply forces below this threshold.

Operation

Commands            

Via Soft Buttons

Read-out

LCD Screen, via the DCA3 Software on the PC

Start

Automatic when force applies to the instrument

Stop Automatic or by pedal

Force Ranges

0-50gf,  0-200gf,  0-1000gf

Force Increasing Rate

Monitored via e-VF Electronic Unit or via the DCA3 Software on the PC

Force Response

in 0.1gf steps

Latency Time

in 0.1s steps

Connection to PC      

via USB cable (A to mini-B) and e-VF Software (DCA3)

Power Requirement

Either battery operated, via USB cable connected to PC, included power supply (100-240 VAC, 50-60Hz)

Operating Temperature

10°C to 40°C; 5% to 95% RH (non-condensing)

Sound Level

Negligible

 

Physical 

Total Weight 0.8 Kg
Shipping Weight 2.7 Kg approx.
Packing Dimensions 46 x 38 x 27 cm

 

Warranty

Warranty 38450 is covered by a 12-month warranty + 12 months after product registration
UB-Care Additional UB-Care can be added for other 12 or 24 months

 

Impaired cutaneous sensation is usually first manife­sted in a loss of light touch detection. The Electronic Von Frey was developed to quantify light touch in the laboratory animal.

The classic instrument for test of touch sensitivity is the Von Frey hair or, more specifically, the Semmes- Weinstein set of Von Frey Hairs, i.e., 20 monofilaments in a linear scale of physical force.

The hair is pressed against the skin, the force applied increases with incre­asing hand pressure, until the hair bends; once the hair is bent, increasing hand approach causes further bend, but negligible additional force on the skin. In this way, a given filament always applies the same force, not subject to variation by the energy of the operator.

The Semmes-Weinstein set can be used on rodents (which respond to light touch of the paw, if they feel it, by a paw withdrawal reflex). However, the involved proce­dure is tedious and time-consuming because several stimulations must be performed for a single test (i.e. a different filament for each force level).

Compared to the classic Von Frey Hairs, the Electronic Von Frey device (e-VF) has the advantage of ensuring a continuous force application along the whole force capacity of the sensor (i.e. 1-1000 gf), by using a rigid metal tip, and the capability to record the animal response automatically.

Moreover, the metal tip used in the e-VF is the same as the one used in the classic Ugo Basile Dy­namic Plantar Aesthesiometer (PN 37450), allowing consistent comparison of results among the two instru­ments.

38450 EVF Electronic Von Frey
38450-001 Electronic Unit               
38450-004 Touch Stimulator Transducer, with handle,  including
38450-310   Glass Prism
38450-330   Filament, with magnetic fixing
52010-325 USB Lead
E-AU 059 Universal Power Supply
E-AU 101 USB pen-drive, including instruction manual and software

Optional

37450-278 Base assembly for plantar stimulation, including support with columns, perforated metal sheet and multiple-configuration animal-enclosure, from 3 to 12 spaces
37450-005 Large Perforated Metal Sheet
37450-045 Large Perforated Metal Sheet, with 4 legs, 40cm height (animal enclosure 37000-007 is not included and should be ordered separately)
37450-085 Large Perforated Metal Sheet, with 4 legs, 80cm height (animal enclosure 37000-007 is not included and should be ordered separately)

 

 

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