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RotaRod for Mice and Rats

Product Code:47650/47750

It assesses motor coordination using natural fear of falling response as motivation. Especially for Parkinson’s, Amyotrophic Lateral Sclerosis (ALS) and other diseases. Simple touch-screen for experiment control and data display.

Simple touch-screen for experiment control and data display. Customizable, uploadable protocols (speed, acceleration, multi-step ramps) for efficiency and repeatability. The device can record up to 5 mice or 4 rats simultaneously. Removable stainless-steel and easy to clean boxes for confining falling mice.

Model
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This product warranty can be extended up to 24 Additional Months.
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Background

  • Current model is the result of over 60 years of expertise and product reliability. After building and naming the original commercial RotaRod, we have retained a strong leadership position through continuous improvement and innovation.
  • It assesses motor coordination by the duration (latency) that a mouse stays on the rod as a function of drum speed. 
  • Range from 3 to 80 RPM ideal for drug screening to assess any side effects on motor coordination including balance and fatigue.
  • Slower speeds suited to motor neuron disease or brain injury studies.
  • More than 6,000 citations of our RotaRod models in published papers.

Easy use, easy care, precision data

  • Easy to operate and monitor experiments using touch-screen. 
  • Software included with every RotaRod enables protocols to be defined in advance. This can be uploaded to the RotaRod for accuracy, efficiency and repeatability; it avoids making any data entry errors during the experiment runtime.
  • Our Rotarod records time the mouse stays on the rotating rod as well as time (latency) of fall. Select and customize speeds (from 3 - 80 RPM in steps of 1 RPM), acceleration and deceleration steps.
  • The device records fall time latency for up to 5 mice or 4 rats simultaneously. Section width is a comfortable 5.8cm. Low fall height is 16cm for mice and 30cm for rats allowing a soft landing into an individual box, preventing any harm to the mouse. 
  • Machined cylinders provide horizontal ridges for sufficient grip. 
  • The Rotarod saves experimental settings with recorded values. The device settings and recorded data can be easily exported in .csv (compatible with all available spreadsheets).
  • Surprisingly quiet operation for reduced stress both for the animal and the operator.
  • Removable stainless-steel boxes facilitate cleaning and prevent mice from escaping when they fall from the rod.
  • Designed for long lasting life, built with the best quality materials in the market, robust and easy to clean

Feature

Benefit

Speed adjustable in the range 3-80 RPM, in steps of 1 RPM                 

It allows huge variety of tests

Constant speed, ramp (accelerat¬ing and decelerating), custom ramp, rocking

Extreme experiment versatility

Stainless-steel trip boxes

Easy to clean and to sterilize, easy to place and to remove; To enclose the animals after the fall

Embedded USB memory stick

The RotaRod does not require connection to PC (Software included) to store and transfer data

X-PAD Software included

User friendly interface; it enables to set up the experiment and to create complex custom ramps

Optional rod enlarger It allows to test different animal models

General

Commands

4,3” touch-screen, usable with gloves

Read-out

Touch-screen and PC (via USB key)

Power Requirement

Universal input 100-240 VAC, 50-60Hz, 40W max.

Sound Level

< 60 dB (A)

Operating Temperature

10° to 40° C

Trip Box Stainless-steel to ease sterilization
Dimensions
Animal Mice Rats Fat Rats
Lanes 5 lanes for mice 4 lanes for Rats 4 lanes
Rod diameter 3 cm 6 cm 8 cm
Rod Width 5,8 cm 8,7 cm 12 cm
Fall Height 16 cm 30 cm 40 cm

Operation

Speed

Adjustable from 3 to 80 RPM, in steps of 1 RPM (Custom ramp mode allows start from 0RPM)

Mode

Constant, ramp, reverse ramp, custom ramp and rocking

Start/Stop

From the touch-screen 

Detection

Trip box magnetic sensor

Results

Time Elapsed, Revolutions, Distance, Speed, Mode for each lane

Data Acquisition

.csv exported file (via USB key)

Data Portability

By USB flash drive

TTL Output

Trip box status, rotating direction, start/stop experiment

Data Out

exported to .cvs

Data In

Import protocol and custom ramps

Physical

Total Weight 11 Kg 15 Kg 17 Kg
Shipping Weight 16 Kg 21 Kg 40 Kg
Dimensions 46 x 28 x 33 cm 55 x 46 x 57 cm 70 x 46 x 65 cm
Packing Dimensions 70 x 36 x 46 cm 70 x 36 x 46 cm 77 x 65 x 83 cm
Warranty
Warranty Mouse Rotarod is covered by a 12 months warranty + 12 months upon product registration
UB-Care Additional UB-Care can be added for additional 12 or 24 months  

The “RotaRod” technique has been originated by a 1957 paper of N.W. Dunham and T.S. Miya and has proved to be of great value in research involving screening of drugs which are potentially active on motor coordination.

Ugo Basile designed the first industrial RotaRod in the 1960s. The name we coined soon became so popular, now everybody knows this instrument as RotaRod! The Rota-Rod is the reference test to screen drugs potentially active, or having side effects, on motor coordination. When an animal falls off its cylinder section onto the trip-box below, the plate boxes and the corresponding magnetic switch is activated, thereby recording the animal endurance time in seconds.

The display shows the actual angular speed (RPM). At the end of a run, the display shows for each animal the running time, the rotation mode and the rotation speed at the time the animal fell off, combined with information pre-set by the user.

RotaRod includes:

47650-320

Stainless-Steel Trip-Box (5 are provided with standard package)

E-AU 101

USB pen drive, including instruction Manual and X-PAD Software Package

Options

47650-325

Mouse RotaRod rod enlargers 60 mm (5 pieces)

N.W. Dunham & T.S. Miya: “A Note on a Simple Apparatus for De­tecting Neurological Deficit in Rats & Mice“ J. Am. Pharmaceut. Assoc., Scientific Edit., XLVI: No. 3, 1957

B.J. Jones & D.J. Roberts: “The Quantitative Measurement of Mo­tor Incoordination in Naive Mice Using an Accelerating Rotarod“ J. Pharm. Pharmac.: 20: 302-304, 1968

Back to: Motory Coordination