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Rat

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Cincinnati Water Maze

Product Code:42500
Category: Mazes, Tracking

The Cincinnati Maze (9T-maze) is an evolution of the Biel Maze with an increased number of interconnected T-mazes.

It is most commonly used as a water maze to avoid scent issues and is used on rats to study egocentric navigation (memory). In order to avoid any possibility of external cue use, the maze is constructed in IR-transparent Perspex to run the experiment in full darkness and ensure that movements are due to egocentric and not allocentric mechanisms.

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The Ugo Basile Cincinnati Maze for rats is a 2x2 mt arena with a training corridor and 9T-mazes interconnected. It is filled with water, has drain and overflow included, together with wheels for easy movement.

The materials used are transparent with IR illumination, to ensure experiments in the darkness. IR-transparents lenses, IR-sensitive cameras and ceiling IR illumination systems can also be provided with Video-Tracking software.

Feature

Benefit

Filled up with water No scent disturbance
Made of IR-transparent material Allows for working in the darkness
Darkness compatibility Allows for dissecting real egocentric memory
Drain, Overflow and Wheels Easy to empty, keep the water level and move, in spite of the large dimensions

Physical

Dimensions 2x2 mt, height (maze walls) 51 cm, height (maze walls + maze base with wheels) 86,5 cm
Total Weight 486 kg

Shipping dimensions

Pallet 2,3(l)x2,3(d)x1,1(h)

Shipping weight 600 kg

 

Warranty

Warranty Cincinnati Maze is covered by a 12-month warranty + 12 after product registration.

 

 

The ability to learn and remembering different locations is encoded in the brain by two systems: one which uses external cues (allocentric) and one using internal cues (egocentric. The structures of the brain involved in the two types of memory are different and hence the ability to run tasks that can dissect them is important. Through the asymmetrical T-mazes which constitute the Cincinnati maze, the number of errors to reach the goal, the time and distance spent are measured to get an index of such memory and ability after an initial training period. Applications are many, from Alzheimer to epilepsy and all those neural phenomena which involve spatial memory, especially when the areas of the brain governing egocentric navigation are to be investigated. An advantage versus the more commonly used Water Maze is that it focuses essential on external cues and it is not possible to count the number of errors as endpoint.

42500 Cincinnati Maze

42500 Cincinnati water maze Rat - IR transparent walls (9 T-maze)

 

 

C. V, Vorhees, M.T. Williams, 2016 “Cincinnati water maze: A review of the development, methods, and evidence as a test of egocentric learning and memory,” Neurotoxicology and Teratology 57

C. V, Vorhees, M.T. Williams, 2024, “Tests for learning and memory in rodent regulatory studies, Current Research in Toxicology

Soto, V. A. Nejtek, D. P. Siderovski, M. F. Salvatore, 2024, “PINK1 knockout rats show premotor cognitive deficits measured through a complex maze”, bioRxiv

J. H. E. Arts, F. Faulhammer, S. Schneider, J. G. W. Salverda, 2023 “Investigations on learning and memory function in extended one-generation reproductive toxicity studies – when considered needed and based on what?”, Critical Reviews in Toxicology

Back to: Mazes, Tracking

IR-transparent mazes for video-tracking

Ugo Basile Infrared transparent mazes offer the highest contrast for the best video-tracking performance, empowering your behavioral experiments.