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Animal
Mouse, Rat

Lickometer (Vogel Test) set-up for Drinking-Conflict experiments

Product Code:45100

The flexible rodent Lactometer - Vogel Test can operate as both a simple software-based lactometer as well as a system for drinking-conflict experiments (coupled with electric shocks). For assessing anxiety and the anxiolytic effect of drugs.

Rat and mouse models. Easy data collection with graphic display. Up to 5 cages can be managed by the software.

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Background

  • In the Drinking-Conflict Vogel paradigm, a water-deprived animal is exposed to a lactometer, and licking events are coupled to electric shocks. The animal is in a motivationally conflicting situation; hence the licking behavior is affected by anxiety and anxiolytic drugs.
  • The Drinking Conflict Vogel test usually consists of three phases:
    • Initial wait (triggered by the first licking event)
    • Shock phase (the sipper is electrified)
    • No-shock phase (no shock is associated to drinking)

Easy control, flexible

  • Choice to use chambers as a general lactometer (without any administration of shocks) or drinking-conflict system (with shocks).
  • Easy data collection. Number and timing of licking events is recorded and graphically displayed for each phase of the experiment.
  • Easy system control. User-friendly software manages the experimental configuration for each cage, collects and saves the experimental data, and also provides a detailed report. Data can be saved as .csv (spreadsheet/Excel) file and .rpt file (a proprietary format which can be opened within the Lactometer software).
  • Time or Number of Licks can be used to determine alternation between shock and no-shock phase, according to the user experimental paradigm.
  • The duration of each phase is user-defined based either on time or on the animal behavior (i.e. the sipper is electrified after a defined number of licking events have occurred).
  • One shocker is required per cage (two-pole sine-wave shocker with adjustable shock intensity)
  • Up to 5 animal cages can be managed. Mouse or rat cages.

 

Feature

Benefit

Multi-Chamber System

Up to 5 Animal Chambers managed by 1 Controller and Software

User friendly proprietary software included

for experiment configuration, data collection and test report

2-Pole Sine-Wave Shocker

Adjustable shock intensity

Versatile protocol management

Can be used as Vogel Test or general Lickometer

General

Power Requirements 115 - 230VAC, 50/60Hz, 25W

Shock

2-Pole Sine-Wave Shocker

Test Settings

Trial, Initial Pause, Time Intervals, Number of Licks to deliver a shock

Data Acquisition

via proprietary software

Data Format

Data are saved as .csv file and .rpt file (proprietary to Lickometer software)

Operating Temperature

10°C to 40°C; 5% to 95% RH (non-condensing)

Sound Level

Negligible

Pollution Degree

≤ 2

Number of Cages

Up to 5 (one shocker for each cage is required)

Physical

Animal Rat Mouse

Dimensions

35(w)x25(d)x30(h)cm

20(w)x24(d)x20(h)cm

Weight

8.5Kg

7.5Kg

Shipping Weight

12Kg

10Kg

Packing Dimensions

80x60x44cm (Control Unit, shocker & one cage)

Warranty

Warranty Lickometer is covered by a 12-month warranty + 12 after product registration 
UB-Care Additional UB-Care can be added for other 12 or 24 months

The Vogel Conflict Test is a conflict based experimental method primarily used in pharmacology. It is used to determine anxiolytic properties of drugs. The Vogel Test predicts drugs that can manage generalized anxiety disorders and acute anxiety states.
Suppressing behaviour through punishment is commonly used to determine the anxiolytic properties of drugs. During the Vogel Test, animals are receive electrical shocks when trying to get either water. Therefore the number of times the animal goes to get water decreases. When anxiolytic drugs are injected, the number of times animals go up to get water increases, even though the animal are still punished.

 

45100 LICKOMETER & DRINKING-CONFLICT TEST, SET-UP FOR RATS

45100-001

5-channel Electronic Unit, including 45100-005 Software

45100-002

Rat Cage

45100-004

2-Pole Sine-Wave Shocker, single channel

E-AU 041

USB pen-drive

45150 LICKOMETER & DRINKING-CONFLICT TEST, SET-UP FOR MICE

45100-001

5-channel Electronic Unit, including 45100-005 Software

45100-003

Mouse Cage

45100-004

2-Pole Sine-Wave Shocker, single channel

E-AU 041

USB pen-drive, including

MULTIPLE-CAGE SET-UP

The following is an example of configuration of a 5-Cage Mouse set-up:

45100-001

5-channel Electronic Unit, including 45100-005 Software

45100-003

Mouse Cage

45100-004

Shocker

 

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