In the late ‘80s Dr. Hargreaves invented a method to assess thermal pain sensation in unrestrained rodents by stimulating the single hind paw and thus allowing for unilateral/contralateral experiments. Ugo Basile made a science-grade instrument to perform this stimulation and automatically measure response, it became a gold-standard with more than 2,000 publications in 2022.

A thermal...

Touch sensitivity is traditionally tested with Von Frey filaments, which is a tedious and experimenter-dependent assay.

The Dynamic Plantar Aesthesiometer is a unique system, which fully automates the amount of force applied by an electromagnetic, silent motor exerting from 0 to 100 grams at a rate adjustable from 0 to 50 seconds.

When the animal responds, by withdrawing its...

Touch sensitivity in unrestrained animals is traditionally tested with Von Frey filaments, which is a tedious and experimenter-dependent assay.

The Electronic Von Frey system solves the multiple measurement (i.e. multiple filaments) issue and the experimenter bias by using a hand-held force sensor with a rigid metal. The scientist gradually increases the force applied to the animal...

Measures endurance, distance and speed. For studying behavioral, physiological, biochemical, and molecular responses to both acute exercise stress and chronic exercise training.

Original product by Ugo Basile is adaptable for use by rats or mice. Easy set up and control using touch screen. Automatic measurement of endurance, distance and speed. Shock grid for aversive stimulus (if...

The RotaRod is a simple test to assess motor function and coordination in rodents. Motor coordination or fatigue can be evaluated by measuring the time the animal stays on a rotating rod before falling. The Rod can rotate at constant, accelerating, rocking (back and forth) or through complex acceleration/deceleration ramps, thanks to the included PC software XPad.

The Ugo Basile...

Measures the weight distribution difference between an injured and unaffected hind paw of a mouse or rat. For the assessment of spontaneous pain in osteoarthritis, bone cancer, nerve injury and post-operative pain studies. Automatic operation reduces operator bias, optimizes repeatability and saves time. Easy to set up. Data visualization to monitor trends. Fast and easy cleaning...

Measures hypersensitivity to thermal (hot and cold) and/or mechanical stimulation of the orofacial area in rats (mouse adaptor available). For research into a wide range of pain conditions involving the trigeminal nerve.

High throughput with data recorded from up to 16 cages with ORO-Software. Real time data display. Non-invasive, respectful test. Comprehensive metrics and easy data...

The Thermal Place Preference test can be considered an evolution of the Hot/Cold plate test and it allows monitoring of temperature preferences by measuring the time spent in two compartments set at two different temperatures.

This two temperature nociception test can be used in a mouse or rat and is composed of a standard hot/cold plate and of an hot plate, connected by a corridor. It...

Accurately measures the nociceptive threshold to infrared heat stimulus on the rat or mouse tail. Used for rapid screening of analgesic drugs by measuring reaction time to heat, even in anesthetized animals, crucial for repeated tests, thanks to the reflexive nature of the tail flick response.

Adjustable I.R. intensity, bright touch-screen display with intuitive controls. Comfortable...

A positive pressure pump (according to Starling’s Ventilator method) for small animals. Assists with breathing during anesthesia and surgery or when an animal has an injury or illness that requires respiratory support.

A positive pressure pump (according to Starling's Ventilator method) for mice. Assists with breathing during anesthesia and surgery or when an animal has an injury or illness that requires respiratory support.

Highly accurate, rate displayed digitally, quiet, durable, high quality, long lifetime. Up to 300 strokes/min. Optimizes oxygenation by minimizing dead space. Range of...

A positive pressure pump (according to Starling's Ventilator method) for cats, rabbits and small animals of similar size. Assists with breathing during anesthesia and surgery or when an animal has an injury or illness that requires respiratory support.

Highly accurate rate displayed digitally, choice of cylinder/piston assemblies (50, 100 ml), quiet, robust, high quality, and long...

Enables recording of spontaneous locomotor activity in rats and mice (individual or groups) using infrared (I.R.) beams. General activity can be an indicator of drug action, toxic substances, neurological damage, or daily rhythms in activity.

Tracks horizontal and vertical activity (rearing). Easily integrated with video-tracking system to measure XY position. Easy touch-buttons,...

Provides and easy to use means of immobilizing an animal for surgery or procedures such as imaging. Gas Anesthesia (compared to injections) is a very quick way to induce total unconsciousness and also assists fast recovery.

High quality compact, modular and virtually unbreakable system. Reliable and precise delivery of the anesthetic gas to animals. Expandable system providing...

Measures the force on a rat or mouse paw according to the Randall-Selitto paw-pressure test, it enables rapid and precise screening of analgesic drugs for anti-nociceptive studies, in healthy or inflamed limbs. The device applies a steady increasing force, starting and stopping using the foot pedal. No calibration required. Digital model with force sensors and electronic unit is also...

The Grip Strength Meter determines the maximum force displayed by an animal in the forelimb, hind-limb or all four limbs, thanks to the full set of accessories included in the Ugo Basile Grip Strength Meter package.

The technique exploits the instinctive resistance of rodents to backward movements and their consequence tendency to grasp (grip) against the pull-back...

Provides simple, reliable and precise calibration for Ugo Basile Plantar Test & Tail Flick and other infrared (I.R.) analgesia meters.

Running wheels provide a convenient method for measuring rodent spontaneous motor activity over long periods of time. Used for research on circadian rhythms, motor function, aging, energy balance, recovering and pain related exercise.

Robust mouse and rat models measure rodent activity across time. Models available with an LCD counter and can also be connected to a Windows PC. Data...

Studies natural curiosity and exploration behavior of rodents when confronted with a new environment (head-plunging, or nose-poking stereotype) according to the method devised by Boissier-Simon. For testing effects of psychotropic drugs on exploratory behavior.

The Boards are available with opaque or transparent walls for use with video tracking software. Mouse or rat versions.

A warmer to provide external heat to animals undergoing surgery. Helps to maintain near-normal body temperature for improved surgical outcomes (such as fewer adverse cardiac events and reduced blood loss).

Preprogrammed animal temperatures, easy-to-use control, lightweight with small footprint. Select Rodent Warmer X2 for simultaneous control of 2 independent heating pads.

Evaluates the spasm-inducing effect of drugs. Typically assesses the effect of bronchodilation agents. Also used for screening substances inducing opposite effects.

Simple, reliable and fast method to assess airflow resistance. High precision recording of volume. Available as a complete set up with a rodent ventilator and data acquisition system.

Used to measure the paw withdrawal reflex when the mouse or rat paw is unexpectedly touched. For evaluating mechanical allodynia and cutaneous sensation levels. Popular non-invasive technique.

Set of 20 monofilaments based on the Semmes Weinstein monofilament set. An ascending series of increasingly stiff filaments (from 0.008 to 300 grams). Features retractable head to protect the...

Convenient, cost-effective solution to confine rodents and small animals for anesthesia procedures.

Models available in 2 sizes – smaller model for rodents and larger model for rabbits and similarly sized animals. Clear Perspex with a sliding lid. Quick connection to anesthesia or euthanasia systems using the 2 tubing connectors.

The hot cold plate test has been the gold standard test for thermal pain tests in rodents for decades. Through the years the devices have been improving and the techniques have become more sophisticated, adding to constant temperature methods also other ones.

The Ugo Basile Hot/Cold plate test includes all the latest technologies necessary to run constant temperature, linear ramping...

The TGR can clearly discriminates temperature-dependent phenotypes or temperature dependent drug effects.

It records and analyses thermal preference/avoidance in mice. For neuropathic pain studies, peripheral neuropathy, temperature sensitivity and insensitivity assessment in basic research, phenotyping and drug screening.

The animal is freely moving, its position is tracked by...

Measures small changes in volume & oedema (fluid retention) to gauge the inflammatory response such as for anti-inflammatory screening tests.

Hands-free operation. Precision measurements. Detects and displays 0.01 ml changes in rodent paw volume. Easy data transfer and software included.

Enlargers for Mouse and Rat RotaRod are available to add multiple parameters to change the complexity of the experiment. Enlargers add-on for RotaRod come with grooves to increase the diameter of the rod or in smooth rubber to increase the diameter of the rod and change the surface from a grooved one to a smooth one. All the types of enlargers can be easily added to the rotating drum thanks to...

The complex wheel add-on for mouse and rat RotaRod introduces an additional complexity element for the animal to be tested. Thanks to the asymmetrical and adjustable bars it increases the test sensitivity and add a higher involvement of motor cortex and hippocampus, as compared to the classic rotarod test.

The Ugo Basile RotaRod is the 1st and original, invented after the Dunham and...