Microwave Brain Fixation system by Muromachi

Additional Info

NEW FEATURE	NEW BENEFIT
Touch-screen	Improved usability
Air-cooled	No water circulation required
CE-certified	No additional declaration required

General
Oscillator	Panasonic Magnetron 2M265-M11
Microwave Power Output	5kW max.( 2-5 kW variable)
Oscillation Frequency	2,450±30MHz
Cooling Requirements	Air Cooling
Exposure Time	0.10-2.99sec (0.01sec steps)
Pausing Time	3 min
Power Consumption	8kVA
Frequency	50 or 60 Hz
Power Requirements	190-240V 30A 3Phase or 380-440V 20A 3Phase
Physical
Dimensions	75(w)x55(d)x128(h)cm
Total Weight	103Kg
Shipping Weight	195Kg approx.
Packing Dimensions	81x100x132cm
Warranty	MMW is covered by a 24-month warranty

In neurochemical studies of the brain, it is of great importance to measure accurately neurochemical events in vivo.

However, it is difficult to perform reproducible measurement of these events because rapid post-mortem changes occur in the brain concentrations of metabolites and neurotransmitters.

With the NEW Microwave Brain Fixation System, the microwave beam stops all brain chemistry at the level present in the living subject, in less than 1 second.

Measuring brain chemistry in-vivo is possible!

MMW-05	MICROWAVE FIXATION SYSTEM 5KW, including 1 Applicator head and 1 animal holder, to be selected
	Applicator Heads
TAW-174P	Applicator Head for Mouse Holder
TAW-424SP	Applicator Head for Rat Holder WJR-S
TAW-424MP	Applicator Head for Rat Holder WJR-M & L
	Water-Jacketed Animal Holders
WJM-24	for mice 15-20g
WJM-28	for Mice 20-40g
WJR-S	for Rats 150-250g
WJR-M	for Rats 250-400g
WJR-L	for Rats 400-500g

Bibliography on MMW

• S. Hedge et al.: “Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice“ Neuropsychopharmacol. 41: 2920-2931, 2016
• T.S. McDonald et al.: “Alterations of Hippocampal Glu­cose Metabolism by Even Versus Uneven Medium Chain Triglycerides“ J. Cerebral Blood Flow & Metabo­lism 34: 153-160, 2014
• B. Sahin et al.: “Evaluation of neuronal phosphoproteins as effectors of caffeine and mediators of striatal ad­enosine A2A receptor signaling” Brain Research 1120: 1-14, 2000
• P. Svenningsson et al.: “DARPP-32 mediates serotoner­gic neurotransmission in the forebrain” PNAS 99 (5), 2002
• G.L. Caporaso et al.: “Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia” Neuropharmacology 39:1637-1644, 2000
• A. Nishi et al.: “Amplification of dopaminergic signaling by a positive feedback loop” PNAS Early Ed. 1-6, 2000