The Cincinnati Maze (9T-maze) is an evolution of the Biel Maze with an increased number of interconnected T-mazes.

It is most commonly used as a water maze to avoid scent issues and is used on rats to study egocentric navigation (memory). In order to avoid any possibility of external cue use, the maze is constructed in IR-transparent Perspex to run the experiment in full darkness and...

Climbing behavior can be of interest for the most diverse applications.

The Ugo Basile automated system replicates its first manual application in the Pain field, for measuring Pain-Depressed behavior. It showed that, while mild analgesics block pain-depressed climbing, strong analgesics fail to alleviate depression of climbing (Santos et al. 2023, “Climbing behavior by mice as an...

The TGR can clearly discriminates temperature-dependent phenotypes or temperature dependent drug effects.

It records and analyses thermal preference/avoidance in mice. For neuropathic pain studies, peripheral neuropathy, temperature sensitivity and insensitivity assessment in basic research, phenotyping and drug screening.

The animal is freely moving, its position is tracked by...

The Operant Fear Conditioning Cage couples a classic skinner box with sound and light cues for complex experiments, as well as standard operant tests and fear conditioning protocols.

When rodents are exposed to inescapable and unpredictable stress, such as forced swim or inescapable foot shock, they often develop deficits in memory and learning tasks (e.g. Active Avoidance) and they often show analgesic reactions (S.I.A. Stress-Induced Analgesia).

The Ugo Basile Set-Up for Learned Helplessness is based on a sophisticated generator of unpredictable random shocks...

Passive Avoidance Test is used to assess memory function based on the association formed between a specific environmental context, which the animal learns to avoid and an aversive stimulus – represented by a mild foot shock.

Efficient and reliable. Silent, automated sliding door divides the dark and light compartments. Systems for mice or rats. Manage up to 4 cages with one...

The cubicle is a sound-attenuating chamber that isolates small animal subjects from distracting ambient light, sound and activity. For behavioral studies including operant behavior (Skinner), self-administration, etc.

High-level soundproof efficacy, noiseless fan, control box. Extra fixtures (speaker and video camera holder) for fear conditioning studies. Available in standard, large...

A set up for testing active avoidance (also called automatic reflex conditioner or shuttle box), i.e. learning to predict the occurrence of an aversive event, based on the presentation of a specific stimulus. Enables performance of a wide range of avoidance experiments using a flexible schedule. Precise detection of avoiding aversive event. Manage up to 4 cages with one controller.

Pre-pulse inhibition of the Startle reflex (PPI) is a phenomenon in which a weak stimulus (sound or light, or air-puff) suppress the startle response to a subsequent stronger startle stimulus (of the same kind).

The interest in this technique is mainly due to the fact that impairment in PPI is normally linked to a dysfunction in the sensorimotor mechanism, which has been shown in...

An essential instrument to measure current on Ugo Basile devices using electric shock grid, such the Fear Conditioning System, Active an Passive avoidance system.

Give the research the ability to measure the electric shock current not measurable by a common volt-meter. To ensure that the same current is delivered on multiple electric shock grids, while performing multiple test in...

The Ugo Basile Fear Conditioning system is composed of:

• Isolation cubicle, including all electronics, fan, IR/VIS lights, camera (up to 16 cubicles can be connected to 1 PC)
• The animal cage is available in different dimensions for rats and mice, plus the observational learning version to allow two animals to see each other. The standard...

The hot cold plate test has been the gold standard test for thermal pain tests in rodents for decades. Through the years the devices have been improving and the techniques have become more sophisticated, adding to constant temperature methods also other ones.

The Ugo Basile Hot/Cold plate test includes all the latest technologies necessary to run constant temperature, linear ramping...

Convenient, cost-effective solution to confine rodents and small animals for anesthesia procedures.

Models available in 2 sizes – smaller model for rodents and larger model for rabbits and similarly sized animals. Clear Perspex with a sliding lid. Quick connection to anesthesia or euthanasia systems using the 2 tubing connectors.

Evaluates the spasm-inducing effect of drugs. Typically assesses the effect of bronchodilation agents. Also used for screening substances inducing opposite effects.

Simple, reliable and fast method to assess airflow resistance. High precision recording of volume. Available as a complete set up with a rodent ventilator and data acquisition system.

Measures the force (or tension) of isolated tissue when its length is constant. Pharmacological responses can be characterized by the contractile/relaxant properties.

Four models available covering range from 0 to 50g. Highest-sensitivity model covers the range 0-800mg. Sturdy construction. Connects to popular data acquisition systems.

A warmer to provide external heat to animals undergoing surgery. Helps to maintain near-normal body temperature for improved surgical outcomes (such as fewer adverse cardiac events and reduced blood loss).

Preprogrammed animal temperatures, easy-to-use control, lightweight with small footprint. Select Rodent Warmer X2 for simultaneous control of 2 independent heating pads.

The Open Field is used to assess exploratory behavior. Validated for use in the measurement of anxiety related behaviors. Also suited to the novel object recognition (NOR) test.

Decreased anxiety leads to increased exploratory behavior. Increased anxiety results in less locomotor motion and preference for the edges of the field.

Studies natural curiosity and exploration behavior of rodents when confronted with a new environment (head-plunging, or nose-poking stereotype) according to the method devised by Boissier-Simon. For testing effects of psychotropic drugs on exploratory behavior.

The Boards are available with opaque or transparent walls for use with video tracking software. Mouse or rat versions.

For investigating isotonic contractions (changes in tissue length) of isolated muscles and measuring small displacements in physiological preparations. Typically used to study the contractile/relaxation effects of drugs.

Perfect for studies using extremely small and fast muscle fibers. Set up a comprehensive system by adding our data acquisition system, organ baths, electrodes and...

Running wheels provide a convenient method for measuring rodent spontaneous motor activity over long periods of time. Used for research on circadian rhythms, motor function, aging, energy balance, recovering and pain related exercise.

Robust mouse and rat models measure rodent activity across time. Models available with an LCD counter and can also be connected to a Windows PC. Data...

Provides simple, reliable and precise calibration for Ugo Basile Plantar Test & Tail Flick and other infrared (I.R.) analgesia meters.

A simple Y-shape design provides rodents with a single choice point with only two alternatives. Widely used to measure preference and spatial memory and learning tasks in laboratory animals.

High quality maze with rat and mouse versions. Provides optimal results with video tracking software (high contrast, non reflective). Surface texture selected for rodent comfort. Easy to set up,...

Widely used to measure preference and spatial memory and learning tasks in laboratory animals. The simple T-shape design provides a single choice point with only two alternatives. Especially for CNS disorder studies.

High quality maze with rat and mouse versions. Provides optimal results with video tracking software (high contrast, non reflective). Surface texture selected for rodent...

A test for spatial learning and long-term memory in rodents. For research into neurocognitive disorders and treatments, aging, drug-abuse, neural systems, neurotransmitters and brain development.

High quality, strong and low weight. Embedded wheels for easy movement. Easy to drain and clean. Add optional Atlantis System to extend test capabilities. Different colors available.

Atlantis System allows platforms in a Morris Water Maze to rise gently to near the surface or go down automatically, using the manual controller or TTL signals. From one to four platform systems available.

Enables extinction protocols on rats or mice. No need to stop the test to manually remove or reposition platforms.

The Barnes Maze is a valid alternative to the water maze to study spatial learning and memory. The motivational drive is the rodent’s instinctive aversion for open spaces and natural preference for dark, “sheltered” spaces.

Reliable and durable. Optimized for use with video-tracking software. Available for mice or rats. Easy to set up, easy to clean.

The Radial Arm Maze has 8 equally spaced arms radiating from a central circular compartment. It can be used for several sophisticated protocols to study spatial, working and reference learning and memory.

The animal can rely on egocentric or allocentric strategies. Working versus reference memory can be assessed by adopting intra or inter trial protocols. Easy to set up, easy to...

Provides accurate recording of isometric or isotonic tissue contraction/release. For studying effects of drugs or electrical stimuli on isolated smooth muscles (including uterus, trachea, gastrointestinal tract, vessel strips, auricle etc) under optimum conditions.

Classic pharmacology tool for research and teaching. Maintains the integrity of live muscle tissue for several hours in...

The Grip Strength Meter determines the maximum force displayed by an animal in the forelimb, hind-limb or all four limbs, thanks to the full set of accessories included in the Ugo Basile Grip Strength Meter package.

The technique exploits the instinctive resistance of rodents to backward movements and their consequence tendency to grasp (grip) against the pull-back...

Measures the force on a rat or mouse paw according to the Randall-Selitto paw-pressure test, it enables rapid and precise screening of analgesic drugs for anti-nociceptive studies, in healthy or inflamed limbs. The device applies a steady increasing force, starting and stopping using the foot pedal. No calibration required. Digital model with force sensors and electronic unit is also...