Antidepressant drugs and depression animal model genetic screening are commonly conducted by using the Tail Suspension Test (TST). This test is based on the aversive effect of hanging a mouse of rat by the tail, which elicits its struggling moving upwards in an attempt to escape (which is obviously not possible).

The struggling attempt tends to be shorter in duration and translates...

The TGR can clearly discriminates temperature-dependent phenotypes or temperature dependent drug effects.

It records and analyses thermal preference/avoidance in mice. For neuropathic pain studies, peripheral neuropathy, temperature sensitivity and insensitivity assessment in basic research, phenotyping and drug screening.

The animal is freely moving, its position is tracked by...

Measures small changes in volume & oedema (fluid retention) to gauge the inflammatory response such as for anti-inflammatory screening tests.

Hands-free operation. Precision measurements. Detects and displays 0.01 ml changes in rodent paw volume. Easy data transfer and software included.

The Ugo Basile Pellet Dispenser works with pellets between 10-20 mg for mice and 22-45 mg for rats. It has an extremely high delivery accuracy thanks to the redundant photobeam check.

An embedded electronic board manages the DC motor and the photodiodes. An ethernet cable connects the Pellet Dispensers to the 8 channel control unit to independently manage up to 8 pellet...

The object recognition test is now among the most commonly used behavioral tests for memory studies in rodents. In its simplest design, an animal is presented with two similar objects during the first session and then one of the two objects is replaced by a new object during a second session or is moved to a different location.

This test is based on the spontaneous tendency of rodents...

The complex wheel add-on for mouse and rat RotaRod introduces an additional complexity element for the animal to be tested. Thanks to the asymmetrical and adjustable bars it increases the test sensitivity and add a higher involvement of motor cortex and hippocampus, as compared to the classic rotarod test.

The Ugo Basile RotaRod is the 1st and original, invented after the Dunham and...

Climbing behavior can be of interest for the most diverse applications.

The Ugo Basile automated system replicates its first manual application in the Pain field, for measuring Pain-Depressed behavior. It showed that, while mild analgesics block pain-depressed climbing, strong analgesics fail to alleviate depression of climbing (Santos et al. 2023, “Climbing behavior by mice as an...