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Animal
Mouse
Videotracking
Traditional

Agora Maze - SocioBox method

Product Code:46573
Category: Mazes, Tracking

Based on where a mouse with free movement spends its time in a central arena area with stimulus animals (familiar/unfamiliar) positioned in cubicles on the outer edge. For research into impairments in social skills that are central to mental disease, and developing tools for their assessment in mouse models as well as smell related behavior (anosmia).

High quality maze that provides optimal results with video tracking software (high contrast, non reflective). Surface texture selected for rodent comfort. Easy to set up, easy to clean.

Model
Are you interested in training program?

Background

  • Originally developed to address the limited availability of reliable tools assessing complex social functions. The method is described by Krueger-Burg et al., in a 2016 paper “The SocioBox: a Novel Paradigm to Assess Complex Social Recognition in Male Mice”. The paradigm studied how readily an experimental mouse could identify an unfamiliar mouse among 5 newly acquainted animals.
  • Ugo Basile’s Agora Maze was recently used by University of Aberdeen for research into smell related behaviors (anosmia), with the purpose of understanding mechanisms of Parkinson’s Disease.

Durable, magnetic attachments, perforated panels

  • High quality, easy to assemble. All materials are selected to be sturdy for reliability and durability.
  • Magnetic attachment of the external boxes for quick, easy replacement of stimulus mice.
  • Addresses the high dependence of smell in mouse social interaction. Transparent (detachable) panels that divide each cubicle are perforated to permit the exchange of odors.
  • Engineered with high contrast, non-reflective materials that are optimal for video tracking.
  • Tests can be automatically recorded by video tracking software for later viewing at a convenient time. Recorded parameters can include time spent, distance travelled by the mice in the central and periphery (cubicle wall) zones of the arena.
  • Anti-slip, naturally warm, maze surface texture is selected for best rodent comfort.
  • Easily and quickly disassembled for easy cleaning.
  • Consists of a 50x50cm grey base. 5 cubicles, and 5 blank walls that are positioned to enclose a central square, with a cross diameter of 34 cm. The 5 cubicles are sized 13x11.5cm.

Features

Benefit

The grey floor gives high contrast with animal

Ideal for Videotracking

One central Arena, and 5 external boxes for stimulus mice

Allows confronting the subject with 5 different stimulus animals

Transparent, perforated dividers

For social interaction and exchange of odors

Magnetic attachment of the external boxes

Designed for quick replacement of stimulus mice

Can be disassembled in seconds

Inter-trial cleaning is quick and easy

 

Physical  

Dimensions

61x58x27(h)cm

Weight

9 Kg

Shipping Dimensions

80x60x44cm

Shipping Weight

14 Kg

 

Warranty

Warranty

Agora Maze is covered by a 12-month warranty + 12 after product registration

UB-Care Additional UB-Care can be added for other 12 or 24 months

 

“A fundamental prerequisite for living in social communities is a highly complex set of social skills that governs interactions between individual members of a group. In consequence, impairments in these social skills, prominently prevalent in human psychiatric disorders such as autism and schizophrenia, have devastating consequences for individuals and society” (Meyer-Lindenberg and Tost, 2012; Lai et al., 2014; Green et al., 2015).
Research has shown that, although human social behavior is generally more complex, humans and animals share some aspects of social behavior; developing new tools for the assessment of social skills in mouse models is essential to further advance in the understanding of these diseases.
The experimental design of the new Agora Maze allows evaluation of preference for social novelty or the propensity to spend time with a previously un-encountered mouse rather than with a familiar mouse.

Ordering

46573

Agora-Maze, Sociability Apparatus for Mice, complete

D. Krueger-Burg, Daniela Winkler et alia: “The SocioBox: a Novel paradigm to Assess Complex Social Recognition in Male Mice” Front. Behav. Neurosci., 11 August 2016 - https://doi.org/10.3389/fnbeh.2016.00151

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