The three-chamber test is the classic test to assess social behavior and memory in rodents. This may range from autism disease to dominance tests and social novelty. During the test one animal is freely moving while the other two are confined into circular grid bar cages.
The Ugo Basile system includes a high contrast or IR-transparent floor for the best quality video-tracking and grid bar cages, which enhance the animal interaction. Walls can be transparent or non-transparent, depending on experimental needs.
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Feature |
Benefit |
|---|---|
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Grey floor |
Gives high contrast with both light and dark animals |
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Metal bottom with special coating |
Gives a slightly rough surface, pleasant for the animals to walk on, and it’s easy to clean |
|
Grid enclosures |
Maximize animal interaction and are available in different sizes/colors |
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Designed for Videotracking |
Works even with the most basic video-tracking software |
|
Transparent or opaque walls and partitions |
Choose the best option for your experimental needs! |
|
For Mice or Rats |
3 different sizes available |
| Physical | |||
|---|---|---|---|
|
Animal |
Mouse Cage |
Rat Cage |
Rat Cage XL |
|
Dimensions |
60 x 40 x 25(h) cm |
120 x 58,5 x 40(h)cm |
120 x 80x40(h)cm - external cage |
|
Cages internal diameter |
7 cm |
15 cm |
15 cm |
| Cages height | 15 cm | 25 cm | 25 cm |
|
Weight |
9Kg |
13Kg |
16Kg |
|
Shipping Weight |
12Kg |
26Kg |
32Kg |
|
Warranty | |||
| Warranty | Sociability are covered by a 12-month warranty + 12 after product registration | ||
| UB-Care | Additional UB-Care can be added for other 12 or 24 months | ||
The initial application of the three-chamber sociability test, J. Crawley was for autism, by comparing the amount of interaction between a novel and a stranger subject.
Additional applications include sociability differences between genders, strains and any other variable, which may end up with a social preference.
Beyond autism, the Sociability test has shown significant translational power also in schizophrenia, where socially disrupted models were performing a worse social novelty inclination.
Procedure-wise, after a period of habituation the subject sociability is determined by measuring the time spent by the freely-moving subject in the proximity of the grid enclosures containing the first unfamiliar (stranger) mouse or rat.
A second stranger is then introduced in the box within its enclosure and the preference for the new mouse/rat can be easily assessed.
| Mouse Cage for Sociability, with opaque grey walls and partitions and lids, complete with following components: | |
|---|---|
|
46503-003 |
Grid Enclosure for Sociability (“stranger” cage) grey, I.D. 7cm, 15cm(h) (2 pieces are provided) |
|
46553-010 |
3-Chambered Opaque Grey Cage, with two doors, 60x40x22(h)cm |
|
M-LM 570 |
Metal Floor, special non-reflective color |
|
Mouse Cage for Sociability, with transparent walls, partitions and lids, complete with following components: | |
|
46503-003 |
Grid Enclosure for Sociability (“stranger” cage) grey, I.D. 7cm, 15cm(h) (2 pieces are provided) |
|
46503-010 |
3-Chambered Transparent Cage, with two doors, 60x40x22(h)cm |
|
46503-320 |
Set of two transparent lids |
|
M-LM 570 |
Metal Floor, special non-reflective color |
|
Mouse Cage for Sociability, with transparent walls, partitions and lids, complete with following components: | |
|
46503-013 |
Grid Enclosure for Sociability (“stranger” cage) white, I.D. 7cm, 15cm(h) (2 pieces are provided) |
|
46503-010 |
3-Chambered Transparent Cage, with two doors, 60x40x22(h)cm |
|
46503-320 |
Set of two transparent lids |
|
M-LM 570 |
Metal Floor, special non-reflective color |
|
Grid Enclosure | |
|
46503-003 |
Grid Enclosure for Sociability (“stranger” cage) grey, I.D. 7cm, 15cm(h) |
|
46503-005 |
Grid Enclosure for Sociability (“stranger” cage) grey, I.D. 10.5cm, 18cm(h) |
|
46503-013 |
Grid Enclosure for Sociability (“stranger” cage) white, I.D. 7cm, 15cm(h) |
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46503-015 |
Grid Enclosure for Sociability (“stranger” cage) white, I.D. 10.5cm, 18cm(h) |
|
46553-320 |
Set of two transparent lids for 46553 |
|
46552 |
Rat Cage for Sociability, with opaque grey walls and partitions, complete with following components: |
|
46552-010 |
3-Chambered Opaque Grey Cage, with two doors, 120x40x40(h)cm |
|
M-LM 1102 |
Metal Floor, special non-reflective color, 120x40cm |
|
46502 |
Rat Cage for Sociability, with transparent walls, partitions and lids, complete with following components: |
|
46502-002 |
Grid Enclosure for Sociability (“stranger” cage) grey, I.D. 15cm, 25cm(h) (2 pieces are provided) |
|
M-LM 1102 |
Metal Floor, special non-reflective color, 120x40cm |
|
M-LM 1340-F |
Metal Floor, special non-reflective color, 120x80cm |
|
46512 |
Rat Cage for Sociability XL, with transparent walls, partitions and lids, complete with following components: |
|
46512-010 |
3-Chambered Transparent Cage, with two doors, 120x80x40(h)cm |
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Videotracking | |
|
60000 |
ANY-maze, flexible video tracking system designed to automate testing in behavioural experiments. Full License, including technical support and all updates for a period of 1 year. |
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47400-040 |
B/W USB Camera, including day&night 2.8-12.0mm varifocal lens, 5m USB cable and ceiling support |
J. J. Nadler et. al., 2004, "Automated apparatus for quantitation of social approach behaviors in mice", Genes Brain Behav.
Amanda J. Mierzwa et. al., 2013, "FGF2 and FGFR1 signaling regulate functional recovery following cuprizone demyelination", Elsevier
A. Papadakakis et. al., 2019, "Music exposure attenuates anxiety- and depression-like behaviors and increases hippocampal spine density in male rats", Elsevier
Carmela Belardo et. al., 2019, "Oral Cann*bidiol Prevents Allodynia and Neurological Dysfunctions in a Mouse Model of Mild Traumatic Brain Injury", Front. Pharmacol.
Maria Elizabeth De Sousa Rodrigues et. al., 2020, "Targeting soluble tumor necrosis factor as a potential intervention to lower risk for late-onset Alzheimer’s disease associated with obesity, metabolic syndrome, and type 2 diabetes", Alzheimer's Research & Therapy
Marissa E. Moore et. al., 2017, "Abnormal social behavior in mice with tyrosinemia type I is associated with an increase of myelin in the cerebral cortex", Metabolic Brain Disease
In addition to the one-year Regular Warranty and in addition to the one-year product registration extended warranty, Ugo Basile offers an Optional Extended Warranty that extends the warranty period for the product for additional one or two years called “UB Care12”/“UB Care24”. Customers may purchase the “UB Care” at the maximum of 3 months after buying. For more detailed information, please contact your local representatives.
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