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Animal
Mouse

Mouse RotaRod

Product Code:47650

Assesses motor coordination using natural fear of falling response as motivation. Especially for drug screening or motor impairment studies.

Simple touchscreen for experiment control and data display. Customizable, uploadable protocols (speeds, acceleration, multi-step ramps) for efficiency and repeatability. Records up to 5 mice simultaneously. Removable, stainless-steel easy-clean boxes for confining falling mice.

Model
This product warranty can be extended up to 24 Additional Months.
Discover more HERE!

Background

  • Current model is the result of over 50 years of expertise and product reliability. After building and naming the original commercial RotaRod, we have retained a strong leadership position through continuous improvement and innovation.
  • Assesses motor coordination by the duration (latency) that a mouse stays on the rod as a function of drum speed. 
  • Range from 3 to 80 RPM ideal for drug screening to assess any side effects on motor coordination including balance and fatigue.
  • Slower speeds suited to motor neuron disease or brain injury studies.
  • More than 5000 citations of our RotaRod models in published papers.

 

Easy use, easy care, precision data

  • Easy to operate and monitor experiments using touchscreen. 
  • Software included with every RotaRod enables protocols to be defined in advance. This can be uploaded to the RotaRod for accuracy, efficiency and repeatability. Avoids making any data entry errors during the experiment runtime.
  • Records time the mouse stays on the rotating rod as well as time (latency) of fall. Select and customize speeds (from 3 - 80 RPM in steps of 1 RPM), acceleration and deceleration steps.
  • Records fall time latency for up to 5 mice simultaneously. Section width is a comfortable 5.7cm. Low fall height is 16cm allowing a soft landing into an individual box, preventing any harm to the mouse. 
  • Machined cylinders provide horizontal ridges for sufficient grip. 
  • Saves experimental settings with recorded values. Customizable layout with drag and drop columns. Presents results in a convenient tree-like structure. Enables users to add information before or after each test. Export settings and recorded data as text, spreadsheet or pdf files.
  • Enables remote diagnosis and internet access – data can be saved to the cloud via Dropbox, OneDrive, Google Drive etc.
  • Surprisingly quiet operation for reduced stress.
  • Removable stainless-steel boxes facilitate cleaning and prevent mice from escaping when they fall from the rod.
  • Frequently purchased with the GSM Grip-Strength Meter.

Feature

Benefit

Speed adjustable in the range

3-80 RPM, in steps of 1 RPM                 

Useful in a variety of tests

Constant speed, ramp (accelerat­ing), multi-step ramp

Extreme versatility

New trip boxes

To enclose the animals, stainless-steel to ease sterilization

Embedded USB memory stick

Does not required connection to PC (software included) to store and transfer data

Brand new Software

user friendly, included as stan­dard, enables setting up the experiment and managing the results from PC or 4"3 touch-screen

 

General

Commands

4,3 inches touch-screen (Resistive)

Read-out

Touch-screen and PC

Power Requirement

Universal input 100-240 VAC, 50-60Hz, 40W max.

Sound Level

< 60 dB (A)

Operating Temperature

10° to 40° C

Trip Box Stainless-steel to ease sterilization
Lanes 5 Mouse lanes

Operation

Speed

Adjustable in the range 3-80 RPM, in steps of 1 RPM

Mode

Forward rotation, Reverse rotation, Ramp (Increasing RPM), Alternated Rotation, Personalised

Start/Stop

From the touch-screen

Detection

Magnetic sensor

Results

Time Elapsed, Revolutions, Distance, Speed, Mode for each lane

Data Acquisition

Via dedicated X-PAD software or .cvs file for PC.

Data Portability

By USB flash drive

TTL Output

Plate Status, Rotating Direction, Speed

Data Out

exported to .cvs

Data In

exported to .cvs, protocol, ramp

Physical

Total Weight 11Kg
Shipping Weight 16Kg
Dimensions 46(w)x28(d)x33(h)cm
Packing Dimensions 70x36x46cm
Warranty
Warranty Mouse Rotarod is covered by a 12-month warranty + 12 after product registration
UB-Care Additional UB-Care can be added for other 12 or 24 months 

The “Rota-Rod” technique has been originated by a 1957 paper of N.W. Dunham and T.S. Miya (see paragraph 9.1-Method Papers) and has proved to be of great value in research involving screening of drugs which are potentially active on motor co-ordination.
Ugo Basile designed the first industrial RotaRod in the 1960s. The name we coined soon became so popular, now everybody knows this instrument as RotaRod!
The Rota-Rod is the reference test to screen drugs potentially active, or having side effects, on motor coordination.
When a rat falls off its cylinder section onto the trip-box below, the plate boxes and the corresponding magnetic switch is activated, thereby recording the animal endurance time in seconds.
The display shows the actual angular speed (RPM). At the end of a run, the display shows for each animal the running time, the rotation mode and the rotation speed at the time the animal fell off, combined with information preset by the user.

47650 Mouse RotaRod

47650-320

Stainless-Steel Trip-Box (5 are provided with standard package)

E-AU 101

USB pen drive, including instruction Manual  andX-PAD Software Package

Options

47650-325

Mouse Rota-Rod rod enlarger set from 30 mm to 60 mm (5 pieces)

47850

Combination Package 47650 Mouse RotaRod and 47750 Rat RotaRod

N.W. Dunham & T.S. Miya: “A Note on a Simple Apparatus for De­tecting Neurological Deficit in Rats & Mice“ J. Am. Pharmaceut. Assoc., Scientific Edit., XLVI: No. 3, 1957

B.J. Jones & D.J. Roberts: “The Quantitative Measurement of Mo­tor Incoordination in Naive Mice Using an Accelerating Rotarod“ J. Pharm. Pharmac.: 20: 302-304, 1968

Back to: Motory Coordination