Motory Coordination, Grip, Strength, Activity
Code: 47650

The 1st, original Mouse RotaRod for motory coordination studies Featured

Ugo Basile RotaRod: 5,000 citations in Google Scholar!

The “Rota-Rod” technique is essential in screening drugs potentially active, or having side effects, on motor coordination. 

50 years ago Ugo Basile designed the original RotaRod, the first industrial Rota Rod, based on the 1957 paper by N.W Dunham and T.S Miya. The 47650 Rota-Rod NG (Next Generation), is an evolution of the original model and the result of many years of research in cooperation with the latest development in behavioral and pharmacological research. 

Since then, our models have been cited in thousands of scientific papers. The name we coined soon became so popular, now everybody knows this device as RotaRod!

What's new in the NG model:

Physically similar to the previous versions, it offers the same reliability, matched with innovative technology! The new model features stainless-steel trip-boxes to facilitate cleaning and confine the animals when they fall off the rod.

The Mouse RotaRod consists of five 3cm diam. cylinders, which are suitably machined to provide grip. Six 25cm diam. dividers make for five lanes, each 5.7cm wide, enabling five mice to be on the rotor simultaneously. The height to fall is 16cm.

A brand new, user friendly software, is included as standard; via the new software, the operator can easily organize the experiment on her/his PC, and upload it to the Rota-Rod via the USB key. The software automatically classifies the data, combining configuration settings with test results; the user can add information, before or after the test. Results appear in a tree-like structure, where columns can be dragged and dropped to customize the layout. Configurations and data are exported as Text, Excel or Pdf reports and can be saved to cloud via DropBox, OneDrive, GoogleDrive.

The experiment can be set and results can be monitored, also via the 4”3 touch-screen.

Remote diagnosis and internet access are provided.

The 47650 combines the same functionality of the previous version, now considered the standard, with additional new features: surprisingly silent operation, much easier experimental organization and data management.

NEXT GENERATION ROTAROD: SAME RELIABILITY, INNOVATIVE TECHNOLOGY!


Additional Info

    FEATURE

    BENEFIT

    Speed adjustable in the range
    5-80 RPM, in steps of 1 RPM                 
    Useful in a variety of tests
    Constant speed, ramp (accelerat­ing), multi-step ramp (NEW!)
    Extreme versatility
    New trip boxes
    To enclose the animals, stainless-steel to ease sterilization
    Embedded USB memory stick
    Does not required connection to PC (software included) to store and transfer data
    Brand new Software
    user friendly, included as stan­dard, enables setting up the experiment and managing the results from PC or 4"3 touch-screen

    General
    Commands 4”3 touch-screen (resistive)
    Read-out on the touch-screen
    Power Requirement Universal input 85-264 VAC, 50-60Hz, 40W max.
    Sound Level < 60 dB (A)
    Operating Temperature 10° to 40° C
    Operation
    Speed adjustable in the range 5-80 RPM, in steps of 1 RPM
    Mode constant, ramp (accelerating), multi-step ramp (NEW!)
    Rotation forward, reverse, rocking
    Rotor Start/Stop on the touch-screen
    Counting Start /Stop each section via its trip box
    Number of Lanes 5
    Trip-Box stainless-steel to ease sterilization
    Drive forward, reverse, rocking
    Data Acquisition via X-PAD software, provided
    Data Portability by USB flash drive
    TTL Output for lane status, rotation and speed
    Data exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive
    Configurations exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive
    Physical
    Total Weight 11Kg
    Shipping Weight 16Kg approx.
    Dimensions 46(w)x28(d)x33(h)cm
    Packing Dimensions 70x36x46cm
    Warranty 47650 is covered by a 24-month warranty

    The “Rota-Rod” technique has been originated by a 1957 paper of N.W. Dunham and T.S. Miya (see paragraph 9.1-Method Papers) and has proved to be of great value in research involving screening of drugs which are potentially active on motor co-ordination.

    Ugo Basile designed the first industrial RotaRod in the 1960s. The name we coined soon became so popular, now everybody knows this instrument as RotaRod!
    The Rota-Rod is the reference test to screen drugs potentially active, or having side effects, on motor coordination.

    When a rat falls off its cylinder section onto the trip-box below, the plate boxes and the corresponding magnetic switch is activated, thereby recording the animal endurance time in seconds.

    The display shows the actual angular speed (RPM). At the end of a run, the display shows for each animal the running time, the rotation mode and the rotation speed at the time the animal fell off, combined with information preset by the user.

    47650 Rat RotaRod NG, complete with standard accessories
    47650-320 Stainless-Steel Trip-Box (5 are provided with standard package)
    E-AU 041

    USB pen drive, including:

    47750-302      Instruction Manual 

    X-PAD Software Package

    OPTIONAL  
    47650-325 Mouse Rota-Rod rod enlarger set from 30 mm to 60 mm (5 pieces)
    47850 Combination Package 47650 Mouse RotaRod and 47750 Rat RotaRod
    • N.W. Dunham & T.S. Miya: “A Note on a Simple Apparatus for De­tecting Neurological Deficit in Rats & Mice“ J. Am. Pharmaceut. Assoc., Scientific Edit., XLVI: No. 3, 1957
    • B.J. Jones & D.J. Roberts: “The Quantitative Measurement of Mo­tor Incoordination in Naive Mice Using an Accelerating Rotarod“ J. Pharm. Pharmac.: 20: 302-304, 1968


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