UB Care
Additional Warranty can be added to this product for other 12 or 24 months.
Discover more about our warranty policy.

Records and analyses thermal preference phenotyping in mice, according to Zimmermann's method. For neuropathic pain studies, temperature sensitivity and insensitivity assessment, always with the animal freely moving and with no user’s intervention.
Novel circular design. Addresses limitations associated with classic devices. Cost effective. Reproducible data.
Features |
Benefits |
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New circular design, internal diameter 45cm, outer diameter 57cm |
Duplicate values, no border effects, no spatial cues |
Thermal Insulated Ring-shaped Aluminum Runway |
More sensitive than previous methods: bias-free, reproducible data |
Heater and cooler on opposite sides, to establish a symmetric gradient |
Gradient setup superior to two-plate choice design |
12 zones per side (specular), 40cm2 each |
Temperature Δ proportionally divided into 12 (in the method paper 15°C-40°C = 2.27°C per zone) |
4 thermocouples embedded in the thermal gradient ring |
The exact temperature gradient measured in real time |
CCD-camera (included in the standard package, with its dedicated support) and ANYmaze video-tracking software |
Behavior recorded automatically during 60 minutes |
The system includes a set of 4 dual (visible/I.R.) lights | Ideal for videotracking: perfect view even in the dark |
General | |
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Controls |
Commands on the heater/cooler front panel |
Preset Temperature Read-out |
On LCD display on the front panel of the thermal units |
Detection |
Via ANY maze specific protocol for TGR |
Sound |
< 60 dB (A) |
Power |
Universal input 85-264 VAC, 50-60Hz, 40W max |
Operation | |
Temperature Range |
Heating Plate: from 20°C to 65°C Heating/cooling Plate: from 4°C to 65°C |
Precision | 0.5°C |
Temperature feedback | By 4 thermocouples monitored in real time by ANYmaze |
Light Intensity (I.R.) | Set by potentiometer with graded scale |
Light Intensity (visible) | Set by potentiometer with graded scale |
Physical | |
Internal diameter | 45 cm |
Outer diameter | 57,5 cm |
Corridor Width | 6 cm |
Wall Height |
24 cm |
Material | IR transparent acrylic |
Dimensions |
87x64x64(h)cm |
Weight |
39Kg |
Shipping Weight |
57Kg |
Packing Dimensions |
100x80x70(h)cm (wooden pallet) |
Warranty | |
Warranty | 35550 is covered by a 12-months warranty + 12 months after product registration |
UB-Care | Additional UB-Care can be added for other 12 or 24 months |
"Currently available behavioral assays to quantify normal cold sensitivity, cold hypersensitivity and cold hyperalgesia in mice have betimes created conflicting results in the literature. Some only capture a limited spectrum of thermal experiences, others are prone to experimenter bias or are not sensitive enough to detect the contribution of ion channels to cold sensing because in mice smaller alterations in cold nociception do not manifest as frank behavioral changes. To overcome current limitations we have designed a novel device that is automated, provides a high degree of freedom, i.e. thermal choice, and eliminates experimenter bias. The device represents a thermal gradient assay designed as a circular running track. It allows discerning exploratory behavior from thermal selection behavior and provides increased accuracy by providing measured values in duplicate and by removing edge artifacts. Our custom-designed automated offline analysis by a blob detection algorithm is devoid of movement artifacts, removes light reflection artifacts and provides an internal quality control parameter which we validated. The assay delivers discrete information on a large range of parameters extracted from the occupancy of thermally defined zones such as preference temperature and skew of the distribution. We demonstrate that the assay allows increasingly accurate phenotyping of thermal sensitivity in transgenic mice by disclosing yet unrecognized details on the phenotypes of TRPM8-, TRPA1- and TRPM8/A1-deficient mice."
from "Comprehensive thermal preference phenotyping in mice using a novel automated circular gradient assay"
35550 Thermal Gradient Ring | |
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35550-001 |
Runway and Thermal Device Assembly |
35550-035 | Visibile and IR Light |
35550-050 | Light and Camera Support |
35550-325 | Camera |
E-AU 101 | USB Key including Instruction Manual |
Control | |
60000 |
Dedicated Video-tracking Software |
F. Touska Z. Winter, A. Mueller, V. Vlachova, J. Larsen and Katharina Zimmermann: "Comprehensive thermal preference phenotyping in mice using a novel automated circular gradient assay" Journal Temperature, Volume 3, 2016 - Issue 1
Additional Warranty can be added to this product for other 12 or 24 months.
Discover more about our warranty policy.