Ugo Basile Supports Pancreatic Cancer Research
November 21st marks the International Pancreatic Cancer Day, an important opportunity to highlight the importance of ongoing research in this challenging field. Pancreatic cancer remains one of the most aggressive and difficult-to-treat malignancies, often diagnosed at advanced stages, making research into effective treatments and diagnostic tools even more vital.
At Ugo Basile, we are proud to contribute to this essential effort by supporting cutting-edge research and providing specialized tools for preclinical studies.
Supporting Scientific Research
Ugo Basile is committed to supporting scientific research not only through the development of products for the scientific community but also by providing financial contributions to scientific studies that can improve people's health and well-being. In this context Ugo Basile srl has recently made a donation to AIRC as part of the "Impresa contro il Cancro" initiative, aimed at supporting scientific research against pancreatic cancer. Our contribution specifically aids the work of Dr. Paola Cappello and her research team from the University of Turin.
Dr. Cappello's project focuses on improving the efficacy of immunotherapy for pancreatic cancer.
The aim of the research project is to improve the efficacy of immunotherapy in pancreatic cancer. The study is particularly focused on the role of interleukin 17A (IL17A), an inflammatory protein that appears to have a protective function for the tumor but could also represent its Achilles' heel. Specifically, the goal is to determine whether reducing the concentration of this molecule can produce effects on the tumor microenvironment capable of influencing the behavior and spread of cancer cells. Additionally, it needs to be demonstrated whether reducing IL17A could reactivate the immune system against the tumor. The outcomes of this research could pave the way for more effective immunotherapy strategies for pancreatic cancer.
Ugo Basile's Contribution to Pancreatic Cancer Research
Our commitment to supporting scientific research dates back to the early 1960s, when the company’s founder, Mr. Ugo Basile, began his work at the University of Milan in the Department of Veterinary Physiology. There, he dedicated himself to developing new apparatus and refining existing research equipment.
in these over 40 years of activity, our company developed a range of innovative devices that are instrumental in preclinical studies investigating tumor-induced pain, systemic effects of cancer, and potential treatment efficacy.
Here’s how some of our devices contribute to this vital research:
Hot/Cold Plate and Dynamic Plantar Aesthesiometer
Although primarily used in pain studies, these devices are crucial for assessing neuropathic pain models. Pancreatic cancer is often associated with significant pain, which can severely impact the quality of life of patients. Preclinical models that mimic tumor-induced pain are essential for evaluating new analgesics and understanding the underlying pain mechanisms.
Learn more about Hot/Cold Plate by Ugo Basile
Learn more about Dynamic Plantar Aesthesiometer by Ugo Basile
Thermal Place Preference System
An advanced version of the hot/cold plate test, the Thermal Place Preference System allows researchers to observe an animal’s preference for temperature gradients. This system can be adapted to study the discomfort or stress responses resulting from pancreatic tumor growth or treatment interventions. Understanding these responses can offer insights into tumor progression and potential therapeutic impacts.
Learn more about Thermal Place Preference by Ugo Basile
Behavioral Monitoring Systems
Assessing the behavior and activity levels of animals in pancreatic cancer models is critical. Our automated systems for tracking rodent behavior provide valuable data on the systemic effects of cancer and the efficacy of potential treatments. These systems can be used to monitor changes in activity, stress, and overall well-being, informing researchers about the comprehensive impact of tumors and therapies.
Discover our Ugo Basile complete range of devices for behavioral studies
At Ugo Basile, we believe in the power of collaboration and innovation to drive meaningful progress in cancer research. By supporting projects like Dr. Cappello's and providing advanced tools for preclinical studies, we hope to contribute to a future where pancreatic cancer becomes a treatable condition.
On this International Pancreatic Cancer Day, we stand with researchers, patients, and families affected by this devastating disease, reaffirming our commitment to the fight against pancreatic cancer.
