Compact Gas Anesthesia Systems and accessories

Additional Info

FEATURE	BENEFIT
Digital flow-meter with high capacity (up to 16 LPM)	Precise and optimal also for multiple animals
Compact and modular	Portable and expandable, multichannel available
NEW, non-refurbished, TEC3 vaporizers	Reliable and precise delivery of the anesthetic gas
Full range of accessories	To compose a versatile full system
Different vaporizers and flowmeter	To match different anesthetizing needs and preferences

Anesthesia Systems series 21100
Dimensions	cm 26 (w) x 18 (d) x 26 (h)
Total Weight	9Kg
Shipping Weight	12Kg approx.
Packing Dimensions	40x39x30cm
02/N20 Anesthesia Systems series 22100
Dimensions	cm 40 (w) x 18 (d) x 26 (h)
Total Weight	11Kg
Shipping Weight	15Kg approx.
Packing Dimensions	67x42x53cm
Warranty	Anesthesia Systems  is covered by a 24-month warranty

In the past decades, there has been a welcome increase in concern for the welfare of laboratory animal: increased use of Anesthetizing Systems is one of the results.

Anaesthetising laboratory animals is a significant improvement of research procedures, since it results in a lack of awareness of any potentially painful or distressing events: in fact, anaesthesia can be used to prevent pain during potentially painful procedures, such as surgery, or to provide a humane means of immobilising an animal for procedures, such as imaging.

When selecting a method of anaesthesia, it is important to consider the required depth and duration of anaesthesia and whether the method selected will cause the minimum of interference with the purpose of the research procedure. In addition the method of anaesthesia should ideally be simple to administer, without causing significant distress to the animal, free from undesirable side effects and allow a smooth and uncomplicated recovery.

Information on potentially suitable anaesthetic regimens can be obtained from a variety of sources, including the Named Veterinary Surgeon, and specialist laboratory animal anaesthesia and general veterinary anaesthesia textbooks.
(from "Anaesthesia | NC3Rs")



Standard Anesthesia Systems for Isoflurane
21050	Basic Single-Output Anesthesia System, including Digital Flowmeter (for O2 or Medical Air) and TEC-3 vaporizer for Isoflurane (vaporizers for other anesthetic agents are available on request)
21100	Single-Output Anesthesia System, including Basic Single-Output Anesthesia System, scavenger (Activated Charcoal Canister), evac tubing
21200	Double-Output Anesthesia System, including 21050, scavenger (Activated Charcoal Canister), evac tubing and dual diverter manifold, for simultaneous connection of nose-cone/mask and induction box
21400	Multiple-Animal Anesthesia System, including 21050, scavenger (Activated Charcoal Canister), evac tubing and Multiple Delivery System, for 4 animals
21600	Multiple-Animal Anesthesia System, including 21050, scavenger (Activated Charcoal Canister), evac tubing and Multiple Delivery System, for 6 animals
Delivery Systems (Masks & Induction Boxes) select from the following accessories, according to your experimental needs and to your animal model:
PS-0525-A	Nose-Cone/Mask for Small Mice, with diaphragm and Inlet Adaptor
PS-0305-A	Nose-Cone/Mask for Large Mice, as above, 3cm diam
PS-0306-A	Nose-Cone/Mask for Small Rats, as above, 4.5cm diam
PS-0307-A	Nose-Cone/Mask for Medium Rats, as above, 5cm diam.
PS-0308-A	Nose-Cone/Mask for Large Rats, as above, 5.5cm diam.
7900	Induction Box for small rodents (mice and rats), 25x13x13 (h) cm
7910	Induction Box, large size, 40x22x21 (h) cm
21100-790	Induction Box for small rodents (mice and rats) 25x13x13(h) cm
Multiple-Output Delivery Systems
PS-0529-02	Dual Diverter Manifold with humidifier (see also 21200)
PS 30-456	Multiple-Animal Delivery System, with 2 Flowmeters
PS 30-457	Multiple-Animal Delivery System, with 3 Flowmeters
PS 30-458	Multiple-Animal Delivery System, with 4 Flowmeters
PS 30-460	Multiple-Animal Delivery System, with 5 Flowmeters
PS 30-459	Multiple-Animal Delivery System, with 6 Flowmeters
Anesthetic Scavenger and Evacuation
PS-0581-00	F/air filter (activated charcoal canister)
PS-0581-01	F/air filter (activated charcoal canister), pkg. of 8
PS-0582	Evac Tubing for F/air, 1.8m with 19mm male x 22m female adaptor
PS-0833	Active Scavenger, to remove the anesthetic agent by applying negative pressure (can also be connected to an activated charcoal canister)
Heating Pads
21100-800M	Rodent Warmer with 21100-810 Mouse Heating Pad
21100-800R	Rodent Warmer with 21100-812 Rat Heating Pad
21100-800C	Rodent Warmer with 21100-814 Cage Heating Pad
21100-304	Rectal Thermal Probe
PS-0811	Delta-Phase Iso-therm Heating Pads (pkg of 3), 20x20x0,65cm. Maintains animal body temperature near 37°C up to several hours. Ideal for NMR
Other Accessories
PS-09	Fill Device for Isoflurane
PS-0949	Fill Device for Halothane
PS-0951	Fill Device for Sevoflurane
SPECIAL SYSTEMS WITH N2O
22100	O2/N2O Anesthesia System,  complete with 2 Analog Flowmeters, TEC-3 vaporizer for Isoflurane (vaporizers for other anesthetic agents are available on request), scavenger (Activated Charcoal Canister), tubing.
TO COMPLETE YOUR EQUIPMENT We also offer a complete line of Ventilators, which includes models for Mouse, Rats, Cat/Rabbit:
28025	Mouse Ventilator, complete with 1ml or 0.5ml (model 28025-5) cylinder/piston assembly & standard accessories. Universal input 85-264 VAC, 50-60Hz
28025-150	Connection Kit for Anesthesia System to Ventilator 28025
7025	Rodent Ventilator, complete with 10ml, 30ml (7025-30) or 5ml (7025-5) cylinder/piston assembly and standard accessories. Universal input 85-264 VAC, 50-60Hz
7025-150	Connection Kit for Anesthesia System to Ventilator 7025
6025	Cat/Rabbit Ventilator, complete with 50ml or 100ml (6025-100) cylinder/piston assembly and standard accessories. Universal input 85-264 VAC, 50-60Hz
6025-150	Connection Kit for Anesthesia System to Ventilator 6025
All ventilators are available with suitable circuit & BNC connector for synchronized START/STOP.

Bibliography on 21100

• Globular chitosan treatment of bovine jugular veins: Evidence of anticalcification efficacy in the subcutaneous rat model AA Krasilnikova, DS Sergeevichev, VV Fomenko… - Cardiovascular Pathology, 2017
• The Development and Use of a Drug-Induced Immunosuppressed Rat-Model to Screen Phela for Mechanism of Immune Stimulation MR Lekhooa, A Walubo, JB du Plessis, MG Matsabisa - Journal of …, 2017
• Dezocine exhibits antihypersensitivity activities in neuropathy through spinal μ-opioid receptor activation and norepinephrine reuptake inhibition YX Wang, XF Mao, TF Li, N Gong, MZ Zhang - Scientific Reports, 2017
• ECoG spectrum changes at different xenon-isoflurane anaesthesia depths B Pavel, CA Acatrinei, M Corbu, CMD Zahiu, AE Rosca… - Romanian Journal of …, 2017
• Molecular signaling underlying bulleyaconitine A (BAA)-induced microglial expression of prodynorphin TF Li, HY Wu, YR Wang, XY Li, YX Wang - Scientific Reports, 2017
• Morroniside, a secoiridoid glycoside from Cornus officinalis, attenuates neuropathic pain by activation of spinal glucagon‐like peptide‐1 receptors M Xu, HY Wu, H Liu, N Gong, YR Wang, YX Wang - British Journal of Pharmacology, 2017
• Влияние прекондиционирования десфлураном на содержание фосфорилированной формы гликоген синтетазыкиназы 3β в эксперименте AВ Лихванцев, AА Гребенчиков, AА Черпаков… - Общая реаниматология, 2017
• Concurrent bullatine A enhances morphine antinociception and inhibits morphine antinociceptive tolerance by indirect activation of spinal κ-opioid receptors Q Huang, ML Sun, Y Chen, XY Li, YX Wang - Journal of Ethnopharmacology, 2016
• Y.X. Wang et alia: "Dezocine exhibits antihypersensitivity activities in neuropathy through spinal μ-opioid receptor activation and norepinephrine reuptake inhibition" Scientific Reports 8: 43137, 2017
• N. Borjini et alia: “Cytokine and Chemokine Alterations in Tissue, CSF, and Plasma in Early Presymptomatic Phase of Experimental Allergic Encephalomyelitis (EAE), in a Rat Model of Multiple Sclerosis” J. of Neuroinflammation 13: 291, 2016
• Q. Huang et alia: “Concurrent Bullatine A Enhances Morphine Antinociception and Inhibits Morphine Antinociceptive Tolerance by Indirect Activation of spiNal κ-Opioid Receptors” J. of Ethnopharmacology 196: 151-159, 2016