Ugo Basile offers a 3-compartment version of the Conditioned Place Preference (CPP) system for mice, providing researchers with maximum flexibility for evaluating the abuse potential of substances and the motivational effects of drugs. The three-compartment model includes a neutral central chamber, which is ideal as a starting point for unbiased testing. All models are fully optimized for use with video-tracking software or visual scoring.
The Conditioned Place Preference system features interchangeable floors optimized for use with video-tracking software or visual scoring, thanks to the grey, high-contrast color and the non-smooth, non-reflective finish.
The system uses interchangeable tactile floors and visual wall patterns to create robust and well-defined contextual cues.
The three-chamber apparatus adds a central neutral compartment, made of smooth, non-patterned plastic. Two doors connect the neutral area to the lateral conditioning chambers.
The neutral area and the time spent in it represent an additional parameter to be evaluated, which adds complexity to data interpretation.
| Feature | Benefit |
|---|---|
|
Interchangeable patterned floors and walls |
The two compartments differ by tactile stimulation |
|
Walls in either compartment can be altered, by replacing the context kit |
The two compartments differ by visual stimulation |
|
High contrast with light or dark animals |
Optimized for Video-Tracking |
|
Specific models and floors for rats or mice |
Designed for multiple-cage systems for high throughput |
|
Physical | |
|---|---|
| Animal | 43553 Mouse (3-compartment) |
|
External Dimensions (handles excluded) |
45,4 x16,2x32(h)cm |
|
Internal Dimensions (lateral compartments) |
16x15x25(h)cm |
| Internal Dimensions (central compartment) | 5X15x25(h)cm |
|
Patterned Floors |
4 interchangeable floors for each cage |
|
Context Walls |
2 interchangeable context kits provided with each cage (striped and checkered) |
|
Warranty | |
| Warranty | Conditioned Place Preference is covered by a 12-month warranty + 12 after product registration |
The CPP paradigm provides information on the rewarding or aversive effects of visible and tactile contextual cues associated with drugs.
This technique has acquired great popularity in research studies involving addiction, being much easier, if compared to drug self-administration procedures.
First, the animal is conditioned to identify one of the two compartments with the drug experience. Then the time spent in each compartments is measured; preference or
aversion to the drug-paired compartment, hence rewarding/aversive properties of drugs, can be easily deducted.
The CPP test only requires the animal to carry out a simple operation (i.e. move from one compartment to the other) to approach or avoid the drug-paired compartment; the animal is expected to spend more time in the drug-paired compartment, if the drug experience produced a positive effect.
The CPP paradigm provides information on the rewarding or aversive effects of visible and tactile contextual cues associated with drugs.
This technique has acquired great popularity in research studies involving addiction, being much easier, if compared to drug self-administration procedures. First, the animal is conditioned to identify one of the two compartments with the drug experience. Then the time spent in each compartment is measured; preference or aversion to the drug-paired compartment, hence rewarding/aversive properties of drugs, can be easily deducted. The CPP test only requires the animal to carry out a simple operation to approach or avoid the drug-paired compartment; the animal is expected to spend more time in the drug-paired compartment, if the drug experience produced a positive effect.
|
Ordering information | |
|---|---|
|
43553-D03 |
Mouse Cage for Conditioned Place Preference (CPP), including 4 interchangeable floors and 2 context kits, with central neutral area and 2 doors to access the experimental chambers, for thetered and non-thetered animals |
In addition to the one-year Regular Warranty and in addition to the one-year product registration extended warranty, Ugo Basile offers an Optional Extended Warranty that extends the warranty period for the product for additional one or two years called “UB Care12”/“UB Care24”. Customers may purchase the “UB Care” at the maximum of 3 months after buying. For more detailed information, please contact your local representatives.
Thermal Conditioned Cabinet is an essential accessory for your TGR setup. It ensures optimal and stable environmental temperature from 0° up to 70° C (32° up to 158°F), improving test reliability and operator comfort. It holds up to two TGR units and provides insulation from light and noise, with built-in air suction and full connectivity to ANY-maze.
Thermal Conditioned Cabinet is an essential accessory for your TGR setup. It ensures optimal and stable environmental temperature from 0° up to 70° C (32° up to 158°F), improving test reliability and operator comfort. It holds up to two TGR units and provides insulation from light and noise, with built-in air suction and full connectivity to ANY-maze.
