Lickometer (Vogel Test) set-up for Drinking-Conflict experiments

Additional Info

FEATURE	BENEFIT
Multi-Chamber System	Up to 5 Animal Chambers managed by 1 Controller and Software
User friendly proprietary software included	for experiment configuration, data collection and test report
2-Pole Sine-Wave Shocker	Adjustable shock intensity
Versatile protocol management	Can be used as Vogel Test or general Lickometer

General
Shock	2-Pole Sine-Wave Shocker
Test Settings	Trial duration, Initial Pause, Time Intervals, Number of Licks to deliver a shock
Data Acquisition	via proprietary software
Data Format	Data are saved as .csv file and .rpt file (proprietary to Lickometer software)
Operating Temperature	10° to 40°C
Sound Level	Negligible
Pollution Degree	≤ 2
Number of Cages	Up to 5 (one shocker for each cage is required)
Physical
Dimensions	35(w)x25(d)x30(h)cm (Rat Cage) 20(w)x24(d)x20(h)cm (Mouse Cage)
Weight	8.5Kg (Rat Set-Up) 7.5Kg (Mouse Set-up)
Shipping Weight	12Kg (Rat Set-Up) 10Kg (Mouse Set-up)
Packing Dimensions	80x60x44cm (Control Unit, shocker & one cage)
Warranty	45100 is covered by a 24-month warranty

The Vogel Conflict Test is a conflict based experimental method primarily used in pharmacology. It is used to determine anxiolytic properties of drugs. The Vogel Test predicts drugs that can manage generalized anxiety disorders and acute anxiety states.

Suppressing behaviour through punishment is commonly used to determine the anxiolytic properties of drugs. During the Vogetl Test, animals are receive electrical shocks when trying to get either water. Therefore the number of times the animal goes to get water decreases. When anxiolytic drugs are injected, the number of times animals go up to get water increases, even though the animal are still punished.

45100	LICKOMETER & DRINKING-CONFLICT TEST, SET-UP FOR RATS
45100-001	5-channel Electronic Unit, including 45100-005 Software
45100-002	Rat Cage
45100-004	2-Pole Sine-Wave Shocker, single channel
E-AU 041	USB pen-drive, including
	45100-302      Instruction Manual
45150	LICKOMETER & DRINKING-CONFLICT TEST, SET-UP FOR MICE
45100-001	5-channel Electronic Unit, including 45100-005 Software
45100-003	Mouse Cage
45100-004	2-Pole Sine-Wave Shocker, single channel
E-AU 041	USB pen-drive, including
	45100-302      Instruction Manual
	MULTIPLE-CAGE SET-UP The following is an example of configuration of a 5-Cage Mouse set-up:
1	45100-001	5-channel Electronic Unit, including 45100-005 Software
5	45100-003	Mouse Cage
5	45100-004	Shocker

Bibliography on 45100

• P. Ohara et alia: "Evidence for a Role of Connexin 43 in Trigeminal Pain Using RNA Interference In Vivo" J. Neurophysiol 100: 3064-3073, 2008
• J.P. Vit et alia: “Silencing the Kir4.1 Potassium Channel Subunit in Satellite Glial Cells of the Rat Trigeminal Ganglion Results in Pain-Like Behavior in the Absence of Nerve Injury “ J. Neurosc. 28(16): 4161-4171, 2008