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Animal
Mouse, Rat
Analgesy-Meter for Mice
Product Code:37216
Category: Pain and Inflammation
Measures the force on a rat or mouse paw according to the Randall-Selitto paw-pressure test, it enables rapid and precise screening of analgesic drugs for anti-nociceptive studies, in healthy or inflamed limbs. The device applies a steady increasing force, starting and stopping using the foot pedal. No calibration required. Digital model with force sensors and electronic unit is also available.
Exerts a steadily increasing force with easy start and stop. No calibration required. Design maximises care for animals. Model with digital reading available.
Background
- Current model based on over 50 years of expertise and continuous product development.
- Assesses the force at which the animal feels pain.
- Typically, the Randall-Selitto method is used as a rapid and sensitive screening of analgesic and anti-inflammatory drugs.
- Rat/mouse and mouse models available with 3 different force ranges.
- More than 1000 published papers citing Ugo Basile.
Rapid and precise screening of analgesic drugs
- Gradually increases pressure on an inflamed animal paw until the animal makes a flinch response.
- The force can be continuously monitored by a pointer moving along a linear scale.
- The paw is placed on a small plinth under a cone-shaped pusher with a rounded tip, which does not hurt the animal (other shapes available on request).
- The 37215 rat/mouse model features 3 force ranges from 0 to 250, 500, 750g.
- The 37216 mouse model features 3 force ranges from 0 to 125, 250, 375grams. Also includes a special chisel-shaped pusher (force applicator).
- No calibration is required. Device is ready for immediate use.
- Convenient hands-free foot pedal for starting or stopping application of the force.
- Use of very low friction coefficient (slippery) Teflon prevents paw injury. If hind paw withdrawal threshold is reached, the animal can quickly remove its paw from the plinth.
- Features a low voltage synchronous motor for low speed and optimum control.
- A digital add-on is available as an option (force transducer plus display).
- Upgrade kit for some older UB Analgesy-Meters. Ask for details!
|
Feature |
Benefits |
|---|---|
| Same instrument, three different force ranges |
Applied force: 37215 from 0 to 250, 500, 750grams (with extra weights) 37216 from 0 to 125, 250, 375grams (with extra weights) |
| No calibration needed | Simple and reliable |
| Classic method since the 1960s | More than 1000 papers published! |
| NEW model with digital reading | Upgrade kit for old UB Analgesy-Meters available |
| General | ||
|---|---|---|
| Power Consumption | 15W | |
| Operating Temperature | 10° to 40° C | |
| Sound Level | Negligible | |
|
Operation | ||
| Start / Stop | By Pedal Switch | |
| 37216 Force Range | From 0 to 125, 250, 375 grams | |
| Force increasing rate | Regulated by the Analgesy-Meter configuration | |
| Power Requirements | 115V 50/60Hz | 230V 50/60Hz |
| Digital data recording | Via optional Analgesy-Meter DAQ 37215-100 | |
|
Physical | ||
| Total Weight | 3.3 Kg | |
| Shipping Weight | 5.4 Kg approx. | |
| Dimensions | 46 x 16 x 14 cm | |
| Packing Dimensions | 55 x 45 x 36 cm | |
|
Warranty | ||
| Warranty | 367215 / 37216 are covered by a 12-month warranty + 12 after product registration | |
| UB-Care | Additional UB-Care can be added for other 12 or 24 months | |
The Ugo Basile Analgesy-Meter has been designed to perform rapid and precise screening of analgesic drugs on the normal and inflamed rat/mouse paw. The instrument is basically a device which exerts an increasing force at a constant rate. This force is continuously monitored by a pointer moving along a linear scale or recorded on the digital interface upon model. The force is applied to the animal’s paw, which is placed on a small plinth under a cone-shaped pusher with a rounded tip.
The plinth is made of Teflon, which is biologically inert and has a very low friction coefficient. Thus, if the animal suddenly withdraws its paw, it slips out easily without being injured.
The operator depresses a pedal-switch to start the mechanism. When the animal reacts, it is free to leave the paw without any researcher action.
When the rat struggles, the operator releases the pedal and reads off the scale the force at which the animal felt pain.
|
37216 Analgesy-Meter, low pressure model, suitable for Mouse - What's in the box? | |
|---|---|
| 37215-001 | Electronic Unit |
| 37215-303 | Pedal Switch, complete with cable |
| 37216-323 | 2 Additional discs Disc M-LM 716-F |
| 37215-326 | Pusher (special chisel-shaped model) |
| 37215-327 | Complete Slide Assembly for 37216 |
| E-AU 101 | USB pen drive, including instruction Manual (on USB pen drive) |
|
Optional | |
| 37215-100 | ANALGESY-METER DAQ Upgrade Kit |
- L.O. Randall and J.J. Selitto: “A Method for Measurement of Analgesic Activity on Inflamed Tissue” Arch. Int. Pharmacodyn. CXI, No. 4: 409-419, 1957
