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Animal
Mouse, Rat

Active Avoidance Set-Up for Rats and Mice (Shuttle-Box)

Product Code:40530

A set up for testing active avoidance. By learning to predict the occurrence of an aversive event based on the presentation of a specific stimulus, the animal avoids the aversive event. Enables performance of a wide range of avoidance experiments using a flexible schedule. Precise detection of avoiding aversive event (moving to the other compartment). Manage up to 4 cages with one controller. Part of the Beehive cage-manager system.

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Background

  • Active avoidance is a fear-motivated associative avoidance task. By learning to predict the occurrence of an aversive event (shock) based on the presentation of a specific stimulus (tone), the animal avoids the aversive event by moving to a different compartment.
  • Serves as an index of learning and allows memory to be assessed.
  • Used in a wide range of studies including behavior genetics, psychopharmacology and behavioral toxicology. More recently these tests have been used in studies of aging, Alzheimer-type dementia and drug development.

 Versatile, flexible schedule, precise detection

  • Enables the researcher to perform a wide range of avoidance experiments, each according to a flexible schedule (using Timeline feature).
  • Precise detection of animal crossing (moving to a different compartment). A tilting floor provides a simple, reliable detection mechanism for scoring animal movement across the two compartments. A partition with an intercommunicating opening at floor level divides the cage.
  • The intuitive electronic unit display controls up to 4 cages, incorporates a constant-current high precision 8-pole shocker and manages data acquisition. 
  • Measures recorded include:
    • Number of avoidances (the mouse crossing to the other compartment during the warning signal)
    • Number of non-responses (the mouse failing to cross to the other compartment during the trial)
    • Response latency (latency to avoid or escape)
    • Number of intertrial responses (i.e. crossing the barrier within the intertrial interval), 
  • Data are stored inside the unit and can be downloaded for further processing or analysis in Excel, Access, etc.
  • Engineered with high contrast, non-reflective materials that are optimal for video tracking.
  • Anti-slip, naturally warm, maze surface texture is selected for best rodent comfort. 
  • System includes a Controller, and a Cage for either rat or mouse. 
  • Part of the expandable Ugo Basile Beehive conditioning-cage project. Using a single touch-screen controller, you manage all cages.

Features

Benefits

Part of the BEEHIVE SYSTEM

the electronic unit encompasses all controls for up to 4 animal cages!

Maximum Flexibility

Configure your own Avoidance-Experiment Schedules via the timeline function

Tilting-floor detection

Reliable and precise detection of animal crossing

Remote Control feature

Makes remote service and software upgrades extremely simple!

Great Versatility

The same controller can manage different conditioning tests. Ask for details!

 

Touch Screen Controller

LCD

12” with resistive touch screen

CPU Module Port

2 USB Port 2.0; 1 Ethernet port 10/100Mb;1 DVI port for external monitor

Peripheral Port

4 output for Sound, Shock and  light; 1 Power supply 12V-2A

Expansion Bus     Connection

2 RJ11 connectors

General 

Shock

Constant current

Shock Intensity

from 0 to 3mA, in 0.1mA steps

Shock Duration

in 0.1s

Visible Light

0-100, in steps of 5%

Sound frequency

100-18.000Hz, in steps of 100Hz

Operating Temperature

10° to 40°C

Pollution Degree

≤ 2

Number of Cages

Up to 4 (with expansion boxes)

Physical 

Dimensions

57x27x30(h)cm, I.D. 48x20x22(h) (40532)

47x18x25(h)cm, I.D. 38x9x17(h)cm (40533)

Weight

5.3 (40532)  

3.5 (40533)  

Shipping Weight

Rat Set-Up  13Kg

Mouse Set-Up 12Kg

Packing Dimensions

80x60x44cm (Control Unit & one cage)

Warranty

Warranty Active Avoidance is covered by a 12-month warranty + 12 after product registration
UB-Care Additional UB-Care can be added for other 12 or 24 months

 

Behavioral scientists are well acquainted with avoidance methods that have been used for several decades, originally by psychologists, who were interested in animal behavior.
These procedures were later exploited by neuroscientists, who specifically perform sys-tematic studies of the behavioral changes mainly produced by brain lesions, to define the functions of different C.N.S. sections.
Avoidance tests were soon extended to several other areas of research such as behavior genetics, psychopharmacology and behavioral toxicology. More recently, such use has become routine in animal model studies of aging and of Alzheimer-type dementia, including the search for new drugs of potential therapeutic value, consisting of attenuation of behavioral deficits.

 

ACTIVE AVOIDANCE SET-UP, RAT

40500-001

Controller with Touch Screen and 8-pole Scrambling Shocker

40530-010

Software and activation for Active Avoidance Test

40532

Rat Cage

52010-323

USB Cable

E-AU 041

USB pen-drive, including

40530-302

Instruction Manual 

ACTIVE AVOIDANCE SET-UP, MOUSE

40500-001

Controller with Touch Screen and 8-pole Scrambling Shocker

40530-010

Software and activation for Active Avoidance Test

40533

Mouse Cage

52010-323

USB Cable

E-AU 041

USB pen-drive, including

40530-302

Instruction Manual 

MULTIPLE-CAGE SET-UP

The following is an example of configuration of a 4-Cage Mouse set-up:

40500-001

Controller with Touch Screen and 8-pole Scrambling Shocker

40550-010

 Software and activation

40533

A.A. Mouse Cage

40500-005

Expansion Box (one is required for each additional cage)

 

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