April 11th as World Parkinson's Day, World Parkinson's Day, a propitious moment to reflect on the strides made in understanding and treating this complex neurodegenerative disorder, impacting movement, quality of life, and independence.

Understanding of Parkinson's has grown significantly over the past decades, but much work remains to be done in the quest to translate understanding of basic Parkinson's biology into new therapies.

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition that affects individuals in various ways, influencing their communication, social interaction, and behavior. Each year on the 2^nd of April we celebrate World Autism Awareness Day, an occasion it's crucial to delve into the intricacies of this condition, fostering understanding and support for those living with autism. Ugo Basile offers two main devices used in studies on autism: the Three-chamber sociability apparatus and the Agora Maze - SocioBox method.

The recent study titled "Thermal Gradient Ring for analysis of temperature-dependent behaviors involving TRP channels in mice" has shed light on this complex interplay, highlighting the crucial role of the Thermal Gradient Ring (TGR) in advancing our understanding of thermosensation.

The Brain Awareness Week is the annual global campaign organized by the Dana Foundation that shines a spotlight on the wonders of the brain and the importance of brain science in understanding and improving human health. Held each March, the Brain Awareness Week brings together scientists, educators, policymakers, and the public to celebrate the complexities of the brain and promote awareness of neurological research and advancements.

Exciting new research alert! Ugo Basile's RotaRod & Dynamic Plantar used to discover how NAAA-regulated lipid signaling in monocytes influences hyperalgesic priming induction in mice, shedding light on chronic pain mechanisms

Although often used in a interchangeable manner, “motor function and motor coordination” have a subtle difference. While “motor function” refers to general motor performance including strength, and in general the ability to execute purposeful movements, “motor coordination” is a slightly more specific concept even more tightly related to measure the harmonious functioning on the muscles and limbs to produce smooth and efficient movements. Read more to discover which Ugo Basile devices are used for these two different applications.

International Epilepsy Day is a global event celebrated annually on the second Monday in February. The initiative is organized by the International Bureau for Epilepsy and the International League Against Epilepsy to promote awareness on epilepsy right around the world.

For this special occasion we explored how Ugo Basile contributes to scientific research for epilepsy, helping to understand this neurological disorder that affects around 50 million people worldwide.

Much has happened since in 1957 Dunham and Miya published on Journal of the American Pharmacological Association the paper “A note on a simple apparatus for detecting neurological deficit in rats and mice”. That “simple apparatus” has been one of the most effective inventions in Animal Behavior with an incredible impact on science with more than 4,000 citations if searched on Google Scholar.

Exciting new research alert! Ugo Basile's Grip Strength Meter to find new therapeutic target in stroke related inflammation.

The three-chamber test is the classic test to assess social behavior and social memory in rodents. This may range from autism disease to dominance tests and social novelty. Additional applications include sociability differences between genders, strains and any other variable, which may end up with a social preference.

The three-chamber sociability test has been used to assess social behaviour in mice with altered GTF2I levels, in order to evaluate the impact of GTF2I dosage on social interactions and preferences.