Coordination motrice test d'aggrippement activite

47200 - Grip-Strength Meter (mice and rats)

Grip-Strength Meter Grip-Strength Meter

The Ugo Basile Grip-Strength Meter automatically measures grip-strength (i.e. peak force and time resistance) of forelimbs and - via the optional grid - hindlimbs in rats and mice. The effects of drugs, toxins, muscle relaxants, disease, ageing or neural damage on muscle strength may be assessed.

The Grip Strength test is a perfect complement to the gold standard Ugo Basile Rota-Rod device for motor coordination and motor function experiments. The effects of drugs, toxins, muscle relaxants, disease, ageing or neural damage on muscle strength may be assessed.

Our device is sold with full optional, including all available grasping tools and grasping grids, and the software.

The animal is placed over a base plate, in front of a grasping bar (either T-shaped or trapeze-shaped, or the optinoal grid), whose height is adjustable. The grasping tool is fitted to a force sensor connected to the Peak Amplifier, which guarantees a reliable and automated detection of the animal response. The force transducer has a maximum applicable force of 1500g, with a resolution 0.1g.

The device can be used as a standalone or connected to a PC via the USB port, for monitoring and data recording: in fact, our GSM comes standard with both a control unit with internal memory where a number of data can be saved, and the new DCA software for signal monitoring, data transfer and analysis. Once saved, data can be browsed on the control unit and/or trasferred to a PC in proprietary , plus Excel (.xlps) or text (.txt) format, to be managed by most statistical analysis packages available on the market.

The Ratemeter (controller) and Slope (software) features, help the researcher to verify that the desired force is applied at a consistent rate

The transducer incorporates a proprietary memory chip to store all calibration parameters, so that no calibration is required for normal use; moreover, the controller will prompt to auto-zeroing routine at every measurement to automatically adjust any offset.

    FEATURE BENEFIT
    Force-Rate monitoring tools (software and LCD display) Pulling force applied at consistent rate
    Automatic Peak Detector Peak pull-force automatically stored
    Bar and trapezeincluded (grid is optional)  Same instrument measures rat and mouse 
    Auto-Zeroing routine at every measurement No calibration required for normal use
    Operation
    Commands                 via soft-buttons
    Read-out multifunction graphic display
    Starting via keys on the Controller front panel
    Force Ranges 0-100gf,  0-500gf,  0-1500gf
    Force Increasing Rate monitored via the Rate-Meter or via the slope function on the PC
    Force Response in 0.1gf steps
    Latency Time in 0.1s steps
    Connection to PC       via USB cable (A to mini-B) and GSM software
    Power Requirement either battery operated, or via USB cable connected to PC or universal converter  (85-264 VAC, 50-60Hz)
    Operating Temperature 10° to 40° C
    Sound Level Negligible
    Pollution Degree ≤ 2
    Physical
    Total weight 4.8Kg
    Shipping Weight 6.5Kg
    Packing Dimensions 46x38x27cm
    Warranty 47200 is covered by a 24-month warranty

    When pulled by the tail, rodents instinctively grab anything they can, to try to stop this involuntary backward movement, until the pulling force overcomes their grip strength. when positioned in front of the GSM bar, or trapeze, or grid, the animal grasps at it.

    After the animal loses its grip on the grasping bar, the peak amplifier automatically records and stores the peak pull-force achieved by the limbs and shows it on the display.

    47200 GSM Grip Strength Meter
    47200-001 Electronic Unit
    47200-002 Force Transducer
    47200-004 Black PVC Base w/13mm Upright
    M-LM 590 Trapeze (Rat)
    M-LM 588 Trapeze (Mouse)
    M-LM 589 T-shaped Bar
    47200-325 Grasping Grid for Mouse
    47200-326 Grasping Grid (partly blind)
    38500-303 External trigger switch (foot pedal)
    52010-325 USB Lead
    E-AU 059 Universal Power Supply
    E-AU 041

    USB pen-drive, including

    47200-302 Instruction Manual  

    DCA Software  

    See Additional Bibliography

    • R. Barone et alia: “Skeletal muscle Heat shock protein 60 increases after endurance training and induces peroxisome proliferator-activated receptor gamma coactivator 1 α1 expression” Scientific Reports 6(19781), 2016 (Mouse) 
    • L. Liu et alia: “Protective role of SIRT5 against motor deficit and dopaminergic degeneration in MPTP-induced mice model of Parkinson's disease” Behav. Brain Res. 281; 215-221, 2015 (Mouse) 
    • G.J. Huang et alia: “Ectopic Cerebellar Cell Migration Causes Maldevelopment of Purkinje Cells and Abnormal Motor Behaviour in Cxcr4 Null Mice”. PLoS ONE 9 (2): e86471, 2014 (Mouse)
    • R. Barone et alia: “Endurance Exercise and Conjugated Linoleic Acid (CLA) Supplementation Up-Regulate CYP17A1 and Stimulate Testostero-ne BiosynthesisPLoS ONE 8 (11): e79686, 2013 (Mouse)
    • N. Lange et alia: “Behavioural and Pharmacological Examinations in a Transgenic Mouse Model of 2 early-onset torsion dystoniaPharmacology, Biochemistry and Behavior 97 (4): 647–655, 2011 (Mouse)
    • T.J. Kornecook et alia: “Isoform-Specific Effects of Apolipoprotein E on Cognitive Performance in Targeted-Replacement Mice Overexpressing Human APPGenes, Brain and Behavior 9: 182-192, 2010 (Mouse
    • D. Carbajal et alia: “D-004, a Lipid Extract From Royal Palm Fruit, Exhibits Antidepressant Effects in the Forced Swim Test and the Tail Suspension Test in MicePharmacology, Biochemistry and Behavior 92: 465-468, 2009 (Mouse)
    • D. Carbajal et alia: “D-004, a Lipid Extract From Royal Palm Fruit, Exhibits Antidepressant Effects in the Forced Swim Test and the Tail Suspension Test in MicePharmacology, Biochemistry and Behavior 92: 465-468, 2009 (Mouse)
    • D. Lafont et alia: “A Novel Role for Receptor Like Protein Tyrosine Phosphatase Zeta in Modulation of Sensorimotor Responses to Noxious Stimuli: Evidences from Knockout Mice StudiesBehav. Brain Res. 201: 29-40, 2009 (Mouse)
    • V. Massicotte et alia: “Prolonged Performance of a High Repetition Low Force Task Induces Bone Adaptation IN Young Adult Rats, but Loss in Mature Rats” Exper. Gerontology 72 : 204-217, 2015 (Rat)
    • M. Savic et alia: Behavioural Characterization of Four Endemic Stachys TaxaPhytother. Res., 2010 (Rat) 
    • A. Coluccia et alia: “Developmental Omega-3 Supplementation Improves Motor Skills in Juvenile-Adult RatsInt. J. Devl Neuroscience 27: 599-605, 2009 (Rat)
    • A. Coluccia et alia: “Late Embryonic Exposure to All-Trans Retinoic Acid Induces a Pattern of Motor” NeuroToxicology 30: 1120–1126, 2009 (Rat)

     

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