Ventilators and Gas Anesthesia

28025 - Mouse Ventilator

Mouse Ventilator Mouse Ventilator

The 28025 Mouse Ventilator is a positive pressure pump (according to Starling's ventilation method), designed for the use with Mice, but also suitable for perinatal Rats and small birds. 

It consists of a variable-speed geared motor linked by a novel variable stroke mechanism to an interchangeable cylinder/piston assembly (1 or 0.5 ml).

The 28025drive consists of a variable speed geared motor linked by a novel variable stroke mechanism to easily interchangeable cylinder/piston assemblies. Their precisely regulated geared-motor, and the special materials of the ventilator kynematics provides the most accurate and reliable stroke rate control of any respirator available.

Motor speed is controlled by an electronic feedback-controlled drive, thus providing the most accurate and reliable stroke rate control of any respirator available. Electronic noise broadcasting is negligible, and the pumps are also quiet to the ear.

The 28025 can be equipped with 0.1 or 1ml cylinder/piston assembly. The back of the 28025 cabinet provides a flat surface where the operating table can be positioned, as close to the animal as possile, to minimize dead spaces. 

The operation of the ventilator may be "paused" by an external TTL logic signal (optional feature). Synchronised START/STOP feature available as optional (series 28125).

    Connections and airflow specifically designed for mice Minimal dead space to improve oxygenation
    High frequency rate (up to 300 strokes/min) Fits mice respiration parameters under anesthesia
    Optional start/stop feature Synchronize with external imaging devices
    Rate 60 to 300 strokes per minute  
    Rate Read-out on digital display  
    Stroke Volume 0.1 to 1 or 0.05 to 0.5 ml, depending on cylinder/piston installed  
    Stroke Volume Scale precision engraved, 0.05 ml divisions  
    Stroke Volume Reproducibility ±2%  
    Power Requirement 115 or 230 V, 50/60 Hz, 10 VA max.  
    Operating Temperature 10° to 40°C  

    28025= via TTL command

    28125= by synchronised command

    Sound Level <60dB  
    Dimensions 20x13x18.5cm  
    Weight 2.5Kg  
    Shipping Weight 5Kg approx.  
    Packing Dimensions 29x26x29cm  
    Warranty 28025s are covered by a 24-month warranty  













    Artificial ventilation, also called artificial respiration is any means of assisting or stimulating respiration in a subject which is not breathing or is not making sufficient respiratory effort on its own.

    Mechanical ventilation is a method to mechanically assist or replace spontaneous breathing: this involves a machine called a ventilator.

    28025 Mouse Ventilator, complete with 1ml cylinder/piston assembly
    28025-010 1ml Cylinder/piston assembly, with base plate
    28025-321 Perspex Lid
    28025-322 Oiler
    28025-323 Cannula -Y connection, tubes, etc., in a plastic case
    E-AU 041

    USB pen drive, including

    28025-302 Instruction Manual

    Other available Models
    28025-5 Mouse Ventilator, complete with 0.5ml cylinder/piston & standard accessories
    Models with Synchronized START/STOP circuit
    28125 Mouse Ventilator, with 1ml cylinder/piston assembly, synchronized
    28125-5 Mouse Ventilator, with 0.5ml cylinder/piston assembly, synchronized
    28025-010 1ml Cylinder/piston assembly, with base plate
    28025-005 5ml Cylinder/piston assembly, with base plate
    28025-150 Connection Kit for Anesthesia System to Ventilator 6025

    See also our Anesthesia Systems, series 21100, the ideal match to our Ventilators

    See Additional Bibliography

    • W. A. Altemeier et alia: “Mouse Models of Acute Lung InjuryRespiratory Medicine Series: 5-23, 2017
    • M. Wang et alia: “The Responses of Pulmonary and Systemic Circulation and Airway to Anaphylactic Mediators in Anesthetized BALB/c MiceLife Sciences 147: 77-84, 2016
    • M.M.J. Farnham et alia: “Surgical Preparation of Mice for Recording Cardiorespiratory Parameters in vivoJ. Neuroscience Methods 248: 41-45, 2015
    • M.S.Karbalaei et alia: “Impaired contractility and detrusor hypertrophy in cavin-1-deficient miceEur.J.Pharmacol, 689 (1-3): 179-185, 2012
    • D. Chen et alia: “Angiotensin Type 1A Receptors in C1 Neurons of the Rostral Ventrolateral Medulla Modulate the Pressor Response to Aversive StressJ.Neurosc. 32 (6): 2051-2061, 2012
    • G. Grände et alia: “Unaltered size selectivity of the glomerular filtration barrier in caveolin-1 knockout miceAm.J.Physiol, 297: F257-262, 2009
    • S. Finotto et alia: “Asthmatic Changes in Mice lacking T-beta mediated by IL-13Intl. Immunology 17, No. 8: 993-1007, 2005

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