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Wednesday, 06 February 2019 16:20

AGORA, a new device for social interaction studies

Agora Maze for social interaction Agora Maze for social interaction Ugo Basile

A new device for Social Interaction studies, introduced at Measuring Behavior 2018.

Based on the SocioBox model (see D. Krueger-Burg et alia: “The SocioBox: a Novel paradigmD. Krueger-Burg et alia: “The SocioBox: a Novel paradigmto Assess Complex Social Recognition in Male Mice”Front. Behav. Neurosci., 11 August 2016 - https://doi.org/10.3389/fnbeh.2016.00151), we have designed a new social interaction cage, the AGORA Maze.

The experimental design of the new Agora Maze allows evaluation of preference for social novelty or the propensity to spend time with a previously un-encountered mouse rather than with a familiar mouse.The main principle of this test is based on the free choice by a subject mouse to spend time in any part of an open circular arena (αγορα, the name is reminiscent of the central public space in ancient Greek city-states, literally meaning “gathering place”) attached to 5 cubicles with an animal inside each.

46573 agora maze (Picture courtesy of Aberdeen University)

The Agora is optimized for videotracking, the ideal tool to automatize the test, allowing the experimenter to record the session without being present in the room. Additional parameters can be recorderd, such as time spent, as well as distance travelled by the mice in the area closer to the wall of the arena and in the centre. For more details, see Agora page and the attached datasheet.

The Agora maze was the subject of a poster presented at Measuring Behavior 2018 by Sheila Sanchez-Garcia, University of Aberdeen: “Agora: a Complex Social Recognition Paradigm”.

 

 

 

Last modified on Wednesday, 06 February 2019 16:20

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