In the late ‘80s Dr. Hargreaves invented a method to assess thermal pain sensation in unrestrained rodents by stimulating the single hind paw and thus allowing for unilateral/contralateral experiments. Ugo Basile made a science-grade instrument to perform this stimulation and automatically measure response, it became a gold-standard with more than 2,000 publications in 2022.

A thermal...

Touch sensitivity is traditionally tested with Von Frey filaments, which is a tedious and experimenter-dependent assay.

The Dynamic Plantar Aesthesiometer is a unique system, which fully automates the amount of force applied by an electromagnetic, silent motor exerting from 0 to 100 grams at a rate adjustable from 0 to 50 seconds.

When the animal responds, by withdrawing its...

Touch sensitivity in unrestrained animals is traditionally tested with Von Frey filaments, which is a tedious and experimenter-dependent assay.

The Electronic Von Frey system solves the multiple measurement (i.e. multiple filaments) issue and the experimenter bias by using a hand-held force sensor with a rigid metal. The scientist gradually increases the force applied to the animal...

Measures endurance, distance and speed. For studying behavioral, physiological, biochemical, and molecular responses to both acute exercise stress and chronic exercise training.

Original product by Ugo Basile is adaptable for use by rats or mice. Easy set up and control using touch screen. Automatic measurement of endurance, distance and speed. Shock grid for aversive stimulus (if...

Measures the weight distribution difference between an injured and unaffected hind paw of a mouse or rat. For the assessment of spontaneous pain in osteoarthritis, bone cancer, nerve injury and post-operative pain studies. Automatic operation reduces operator bias, optimizes repeatability and saves time. Easy to set up. Data visualization to monitor trends. Fast and easy cleaning...

Measures hypersensitivity to thermal (hot and cold) and/or mechanical stimulation of the orofacial area in rats (mouse adaptor available). For research into a wide range of pain conditions involving the trigeminal nerve.

High throughput with data recorded from up to 16 cages with ORO-Software. Real time data display. Non-invasive, respectful test. Comprehensive metrics and easy data...

The Thermal Place Preference test can be considered an evolution of the Hot/Cold plate test and it allows monitoring of temperature preferences by measuring the time spent in two compartments set at two different temperatures.

This two temperature nociception test can be used in a mouse or rat and is composed of a standard hot/cold plate and of an hot plate, connected by a corridor. It...

This software enables researchers to study behavior in a more reliable and consistent way and over longer time periods than if they were using direct observation or manual recording.

Highly advanced, comprehensive video-tracking system. The software couples an unrivalled depth of features with a simple, familiar design, to provide automated testing in virtually any behavioral...

Accurately measures the nociceptive threshold to infrared heat stimulus on the rat or mouse tail. Used for rapid screening of analgesic drugs by measuring reaction time to heat, even in anesthetized animals, crucial for repeated tests, thanks to the reflexive nature of the tail flick response.

Adjustable I.R. intensity, bright touch-screen display with intuitive controls. Comfortable...

Measures the force on a rat or mouse paw according to the Randall-Selitto paw-pressure test, it enables rapid and precise screening of analgesic drugs for anti-nociceptive studies, in healthy or inflamed limbs. The device applies a steady increasing force, starting and stopping using the foot pedal. No calibration required. Digital model with force sensors and electronic unit is also...

Compact, direct current (DC) Lesion Maker for localized electrolytic lesions in the brain.

Isolated, regulated DC output for electrical safety. Two operating modes: Continuous and Timed.

For stereotaxic surgery using rats or other small animals. Can be used to locate targets for implantation of devices, stimulation or injections.

Smooth, consistent movements with rapid positioning. Time-proven 'U'-Frame design provides stability and adaptability. Integrated warming base can be activated for better surgical outcomes.

The KDS Legato series is a range of advanced, precision syringe pumps. For applications requiring high metering precision at low, pulse-free flow rates.

Intuitive touch screen allows user to easily define complex injection protocols. Display presents real time data.

Provides accurate recording of isometric or isotonic tissue contraction/release. For studying effects of drugs or electrical stimuli on isolated smooth muscles (including uterus, trachea, gastrointestinal tract, vessel strips, auricle etc) under optimum conditions.

Classic pharmacology tool for research and teaching. Maintains the integrity of live muscle tissue for several hours in...

Provides simple, reliable and precise calibration for Ugo Basile Plantar Test & Tail Flick and other infrared (I.R.) analgesia meters.

The Elevated Zero-Maze is an alternative model to the Elevated Plus Maze (EPM). Its circular design provides a smoother transition from closed to open space. The model is based on the rodent's instinctive tendency to explore novel environments and also to avoid unprotected open and elevated spaces. For neurobiological anxiety research.

High quality maze with surface texture selected...

The elevated plus maze (EPM) is used to measure anxiety in rats and mice. The model is based on the rodent's instinctive tendency to explore novel environments and also to avoid unprotected open and elevated spaces. For neurobiological anxiety research.

High quality maze with surface texture selected for best rodent comfort. Optimized for use with video tracking software (high...

A warmer to provide external heat to animals undergoing surgery. Helps to maintain near-normal body temperature for improved surgical outcomes (such as fewer adverse cardiac events and reduced blood loss).

Preprogrammed animal temperatures, easy-to-use control, lightweight with small footprint. Select Rodent Warmer X2 for simultaneous control of 2 independent heating pads.

Automatically scores wheel rotations, corresponding to rodent escape behaviors. A primary screening test for antidepressants.

Automates up to 40 tests simultaneously for high throughput. Durable, easy to assemble. Optimized for use with video tracking software.

Used to measure the paw withdrawal reflex when the mouse or rat paw is unexpectedly touched. For evaluating mechanical allodynia and cutaneous sensation levels. Popular non-invasive technique.

Set of 20 monofilaments based on the Semmes Weinstein monofilament set. An ascending series of increasingly stiff filaments (from 0.008 to 300 grams). Features retractable head to protect the...

The hot cold plate test has been the gold standard test for thermal pain tests in rodents for decades. Through the years the devices have been improving and the techniques have become more sophisticated, adding to constant temperature methods also other ones.

The Ugo Basile Hot/Cold plate test includes all the latest technologies necessary to run constant temperature, linear ramping...

The Ugo Basile Fear Conditioning system is composed of:

• Isolation cubicle, including all electronics, fan, IR/VIS lights, camera (up to 16 cubicles can be connected to 1 PC)
• The animal cage is available in different dimensions for rats and mice, plus the observational learning version to allow two animals to see each other. The standard...

An essential instrument to measure current on Ugo Basile devices using electric shock grid, such the Fear Conditioning System, Active an Passive avoidance system.

Give the research the ability to measure the electric shock current not measurable by a common volt-meter. To ensure that the same current is delivered on multiple electric shock grids, while performing multiple test in...

The Operant Fear Conditioning Cage couples a classic skinner box with sound and light cues for complex experiments, as well as standard operant tests and fear conditioning protocols.

The TGR can clearly discriminates temperature-dependent phenotypes or temperature dependent drug effects.

It records and analyses thermal preference/avoidance in mice. For neuropathic pain studies, peripheral neuropathy, temperature sensitivity and insensitivity assessment in basic research, phenotyping and drug screening.

The animal is freely moving, its position is tracked by...