In the late ‘80s Dr. Hargreaves invented a method to assess thermal pain sensation in unrestrained rodents by stimulating the single hind paw and thus allowing for unilateral/contralateral experiments. Ugo Basile made a science-grade instrument to perform this stimulation and automatically measure response, it became a gold-standard with more than 2,000 publications in 2022.

A thermal...

Measures endurance, distance and speed. For studying behavioral, physiological, biochemical, and molecular responses to both acute exercise stress and chronic exercise training.

Original product by Ugo Basile is adaptable for use by rats or mice. Easy set up and control using touch screen. Automatic measurement of endurance, distance and speed. Shock grid for aversive stimulus (if...

Versatile, automated modular device empowers researchers to assemble a custom configuration perfectly suited to spatial learning and spatial memory studies in rats or mice.

The same modular device can be transformed into automated radial, Y, T and Delta mazes by simply rearranging the arms.

Surface texture is selected for best rodent comfort as well as optimal results with...

Measures the weight distribution difference between an injured and unaffected hind paw of a mouse or rat. For the assessment of spontaneous pain in osteoarthritis, bone cancer, nerve injury and post-operative pain studies. Automatic operation reduces operator bias, optimizes repeatability and saves time. Easy to set up. Data visualization to monitor trends. Fast and easy cleaning...

Measures hypersensitivity to thermal (hot and cold) and/or mechanical stimulation of the orofacial area in rats (mouse adaptor available). For research into a wide range of pain conditions involving the trigeminal nerve.

High throughput with data recorded from up to 16 cages with ORO-Software. Real time data display. Non-invasive, respectful test. Comprehensive metrics and easy data...

The Thermal Place Preference test can be considered an evolution of the Hot/Cold plate test and it allows monitoring of temperature preferences by measuring the time spent in two compartments set at two different temperatures.

This two temperature nociception test can be used in a mouse or rat and is composed of a standard hot/cold plate and of an hot plate, connected by a corridor. It...

This software enables researchers to study behavior in a more reliable and consistent way and over longer time periods than if they were using direct observation or manual recording.

Highly advanced, comprehensive video-tracking system. The software couples an unrivalled depth of features with a simple, familiar design, to provide automated testing in virtually any behavioral...

Accurately measures the nociceptive threshold to infrared heat stimulus on the rat or mouse tail. Used for rapid screening of analgesic drugs by measuring reaction time to heat, even in anesthetized animals, crucial for repeated tests, thanks to the reflexive nature of the tail flick response.

Adjustable I.R. intensity, bright touch-screen display with intuitive controls. Comfortable...

To perform Light/Dark Test with rats or mice for assessing anxiety. Useful in identifying and/or screening of anxiolytic and anxiogenic agents.

High quality maze with rat and mouse versions. Provides optimal results with video tracking software (high contrast, non reflective). Surface texture selected for rodent comfort. Easy to set up, easy to clean.

Measures the force on a rat or mouse paw according to the Randall-Selitto paw-pressure test, it enables rapid and precise screening of analgesic drugs for anti-nociceptive studies, in healthy or inflamed limbs. The device applies a steady increasing force, starting and stopping using the foot pedal. No calibration required. Digital model with force sensors and electronic unit is also...

The Radial Arm Maze has 8 equally spaced arms radiating from a central circular compartment. It can be used for several sophisticated protocols to study spatial, working and reference learning and memory.

The animal can rely on egocentric or allocentric strategies. Working versus reference memory can be assessed by adopting intra or inter trial protocols. Easy to set up, easy to...

The Barnes Maze is a valid alternative to the water maze to study spatial learning and memory. The motivational drive is the rodent’s instinctive aversion for open spaces and natural preference for dark, “sheltered” spaces.

Reliable and durable. Optimized for use with video-tracking software. Available for mice or rats. Easy to set up, easy to clean.

Atlantis System allows platforms in a Morris Water Maze to rise gently to near the surface or go down automatically, using the manual controller or TTL signals. From one to four platform systems available.

Enables extinction protocols on rats or mice. No need to stop the test to manually remove or reposition platforms.

A test for spatial learning and long-term memory in rodents. For research into neurocognitive disorders and treatments, aging, drug-abuse, neural systems, neurotransmitters and brain development.

High quality, strong and low weight. Embedded wheels for easy movement. Easy to drain and clean. Add optional Atlantis System to extend test capabilities. Different colors available.

Widely used to measure preference and spatial memory and learning tasks in laboratory animals. The simple T-shape design provides a single choice point with only two alternatives. Especially for CNS disorder studies.

High quality maze with rat and mouse versions. Provides optimal results with video tracking software (high contrast, non reflective). Surface texture selected for rodent...

A simple Y-shape design provides rodents with a single choice point with only two alternatives. Widely used to measure preference and spatial memory and learning tasks in laboratory animals.

High quality maze with rat and mouse versions. Provides optimal results with video tracking software (high contrast, non reflective). Surface texture selected for rodent comfort. Easy to set up,...

Provides simple, reliable and precise calibration for Ugo Basile Plantar Test & Tail Flick and other infrared (I.R.) analgesia meters.

The Open Field is used to assess exploratory behavior. Validated for use in the measurement of anxiety related behaviors. Also suited to the novel object recognition (NOR) test.

Decreased anxiety leads to increased exploratory behavior. Increased anxiety results in less locomotor motion and preference for the edges of the field.

The hot cold plate test has been the gold standard test for thermal pain tests in rodents for decades. Through the years the devices have been improving and the techniques have become more sophisticated, adding to constant temperature methods also other ones.

The Ugo Basile Hot/Cold plate test includes all the latest technologies necessary to run constant temperature, linear ramping...

The Ugo Basile Fear Conditioning system is composed of:

• Isolation cubicle, including all electronics, fan, IR/VIS lights, camera (up to 16 cubicles can be connected to 1 PC)
• The animal cage is available in different dimensions for rats and mice, plus the observational learning version to allow two animals to see each other. The standard...

An essential instrument to measure current on Ugo Basile devices using electric shock grid, such the Fear Conditioning System, Active an Passive avoidance system.

Give the research the ability to measure the electric shock current not measurable by a common volt-meter. To ensure that the same current is delivered on multiple electric shock grids, while performing multiple test in...

Pre-pulse inhibition of the Startle reflex (PPI) is a phenomenon in which a weak stimulus (sound or light, or air-puff) suppress the startle response to a subsequent stronger startle stimulus (of the same kind).

The interest in this technique is mainly due to the fact that impairment in PPI is normally linked to a dysfunction in the sensorimotor mechanism, which has been shown in...

A set up for testing active avoidance (also called automatic reflex conditioner or shuttle box), i.e. learning to predict the occurrence of an aversive event, based on the presentation of a specific stimulus. Enables performance of a wide range of avoidance experiments using a flexible schedule. Precise detection of avoiding aversive event. Manage up to 4 cages with one controller.

The cubicle is a sound-attenuating chamber that isolates small animal subjects from distracting ambient light, sound and activity. For behavioral studies including operant behavior (Skinner), self-administration, etc.

High-level soundproof efficacy, noiseless fan, control box. Extra fixtures (speaker and video camera holder) for fear conditioning studies. Available in standard, large...

Passive Avoidance Test is used to assess memory function based on the association formed between a specific environmental context, which the animal learns to avoid and an aversive stimulus – represented by a mild foot shock.

Efficient and reliable. Silent, automated sliding door divides the dark and light compartments. Systems for mice or rats. Manage up to 4 cages with one...

When rodents are exposed to inescapable and unpredictable stress, such as forced swim or inescapable foot shock, they often develop deficits in memory and learning tasks (e.g. Active Avoidance) and they often show analgesic reactions (S.I.A. Stress-Induced Analgesia).

The Ugo Basile Set-Up for Learned Helplessness is based on a sophisticated generator of unpredictable random shocks...

The Operant Fear Conditioning Cage couples a classic skinner box with sound and light cues for complex experiments, as well as standard operant tests and fear conditioning protocols.

The TGR can clearly discriminates temperature-dependent phenotypes or temperature dependent drug effects.

It records and analyses thermal preference/avoidance in mice. For neuropathic pain studies, peripheral neuropathy, temperature sensitivity and insensitivity assessment in basic research, phenotyping and drug screening.

The animal is freely moving, its position is tracked by...

The Cincinnati Maze (9T-maze) is an evolution of the Biel Maze with an increased number of interconnected T-mazes.

It is most commonly used as a water maze to avoid scent issues and is used on rats to study egocentric navigation (memory). In order to avoid any possibility of external cue use, the maze is constructed in IR-transparent Perspex to run the experiment in full darkness and...