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Animal
Mouse

Rotometer - Recording of Rotation Activity for unrestrained mice

Product Code:43000

Counts rotations in unrestrained, free roaming mice. Popular method for screening the behavioral effects of drugs. Also for Parkinson’s Disease studies.

Automatically counts clockwise and counter clockwise rotations. Ugo Basile Original design – no tether required for the animal. Works with a magnet attached or injected into the mouse.

Model
Are you interested in training program?

Background

  • There are several well-characterized causes for animals to exhibit rotational behavior:
    • Uneven/unilateral higher expression of levels of neurotransmitters (such as GABA or dopamine). 
    • Developmental anomalies
    • Anxiety/stress 
    • Exposure to some drugs, or drug abuse, or drug withdrawal 
    • Physical lesions 
  • Traditionally rotation tests can be constrained by the use of tethers. Our original design measures unrestrained rotational behavior in a circular open field using the latest technologies that enable the arena to be quite large while keeping the magnet very small.

Automatic counter, easy to use

  • Automatically counts clockwise (CW) and counter clockwise (CCW) rotations in free-moving animals using a magnetic field detection system. Digital read-out displays accrued rotations. No restraints or jackets are used.
  • Quick and simple to use: no training required. Tests are conducted by simply attaching a tiny magnet (the size of a grain of rice) to the animal tail or nape.
  • For longer-term tests, we offer a syringe kit with small injectable magnets encapsulated within a proven biocompatible material that does not interfere with animal behavior. Magnets are easy to inject using the included animal ID transponder syringe.
  • Standalone turnkey system that also features Portable Memory Stick technology, USB interface and software for connection to PC.
  • The circular arena for mouse (or small rat) is 20cm diam. Clear Perspex cylinder enclosure is 25cm tall.

Feature

Benefit

No harness, no jacket, no tether is required

The animal is TRULY FREE AND UNRESTRAINED

Extremely sensitive

The magnet attached to tha animal is very small (2x15mm)

The magnet can be attached anywhere on the animal

Reduce the stress to the animal at its minimum

 

General

Commands

Via “soft keys”

Starting

Via command key

Read-out

Multifunction graphic display

Print-Out

By optional thermal MiniPrinter 57145

Power Requirement

Universal input 100-240 VAC, 50-60Hz, 20W max.

Sound Level

Less than 60 dB (A)

Operating Temperature

18° to 40° C

Connection to PC

Via USB (Type A & B) 

Data Portability

Via USB flash drive, CUB Software

Physical 

Total Weight

3.5Kg

Shipping Weight

7Kg approx.

Dimensions

25(w)x37(d)x16(h)cm (without restrainer)

Dimensions (restrainer)

20cm diam. x 25(h)cm  

Packing Dimensions

68x34x28cm

Warranty

Warranty Rotometer is covered by a 12-month warranty + 12 after product registration
UB-Care Additional UB-Care can be added for other 12 or 24 months

 

The Rotometer is widely used in research on motor assessment tests. Rotometer is also used in traumatic and acquired brain injury research and spinal cord injury research.
There are several well-characterized causes for animals to exhibit rotational behavior:
• Uneven/unilateral higher expression of levels of neurotransmitters (such as GABA or dopamine). Some brain tumors can cause aberrant expression levels to occur. Injury may also interfere with proper neurotransmitter expression, and/or cause some localized change in neurotransmitter expression
• Developmental anomalies can also cause rotational behavior
• Anxiety/stress may cause this aberrant behavior
• Exposure to some drugs, or drug abuse, or withdrawal from some drugs, all may have rotational sequelae.
• Physical lesions also can cause rotational behavior in an animal
To quantify rotational behavior in a freely moving animal is a significant development

 

43000 Rotometer

43000-001

Rotometer Electronic Unit

35100-286

Perspex Animal Restrainer

E-AU 101

USB Key including Instruction Manual

52050-13CUB Data Acquisition Software Package

Options

43000-321

Syringe kit, including 1 syringe and 2 injectable magnets

43000-012

Magnets kit (including 10 magnets) 2x12 mm

43000-052

Magnets kit (including 50 magnets) 2x12 mm

43000-015

Magnets kit (including 10 magnets) 2x15 mm

43000-055

Magnets kit (including 50 magnets) 2x15 mm

 

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