Pharmacologie ect lmd
Code: 57800

Générateur ECT

The ECT apparatus (Electro Convulsive Therapy) is specially designed for neurochemical and neuropharmacological research. 

A constant current output is used, which ensures reproducible results and accurate determination of the EC threshold while also pinpointing any variations in the threshold brought about by drugs having a specific action on the cortex and sub-cortical regions. The shock parameters have been selected after consulting the most relevant literature, to supply the most suitable range when operating with mice or rats.                                             

Consistent reproducible current levels are produced by feedback circuitry that adjust for variance in impedance of the contact from animal to animal.

The impedance to the animal can be pre-measured and displayed, and a warning signal flashes if the impedance is too great to deliver the desired current level.

The standard auricular electrodes supplied (see main picture) allow a single operator to deliver shock to a number of subjects in a short time. Optional corneal electrodes are available as optional.

The special output circuit enables any type of electrode to be used.

 

Informations supplémentaires

    FEATURE BENEFIT
    Optional analogue output     Can be connected to oscilloscope
    Any type of electrode can be used     Allows for virtually any procedure
    Feedback circuitry Compensates for impedance variability due to animal-electrode contact  
    General  
    Commands via thumb-wheels
    Read-out liquid-crystal display
    Starting via keys on the electronic unit panel
    Power Requirement 115 or 230 V, 50/60 Hz, 75 W max.
    Operating Temperature 15° to 30° C
    Sound Level < 70 dB (A)
    Shock Pulse Train  
    Rectangular Positive  Pulses by H.V. Transformer
    Constant Current by feedback network
    Pulse Rise & Fall Time 20 µs
    Pulse Width (ms) 0.1 to 0.9 in 0.1 ms steps ± 1%
    Frequency (pulses/s) 1 to 299 in 1 pulse/s steps ± 1%
    Shock Duration 0.1 to 9.9 in 0.1 s steps ± 1%
    Pulse Voltage max. 2.5 KV
    Current Range 1 to 99 mA in 1 mA steps ± 2%
    Output Load (at max current) min. 0 Ohm – max. 25 KOhm
    KOhm Display 0 to 199 KOhm, 1 KOhm resolution
    Physical  
    Total Weight 3.42Kg
    Shipping Weight 5.0Kg approx.
    Dimensions 276(w)x37(d)x13(h)cm
    Packing Dimensions 45x34x26cm
    Warranty  
    Warranty 57800 is covered by a 24-month warranty.

     

     

                                                                                                             

     

    The ECT Apparatus is specially designed for neurochemical and neuropharmacological research. It is particularly useful for:

    • general screening of potentially neurotropic substances
    • evaluating the depressant or stimulating action of drugs on the CNS
    • endocrinological investigations on the relationship between the nervous sys-tem and the hypophysis.

    A constant current output is used which ensures reproducible results and accurate determination of the EC threshold while also pinpointing any variation in the threshold brought about by drugs having specific action on the cortex and subcortical regions.

    The shock parameters have been selected after consulting the most recent literature, in order to determinate the range of requirements likely to be needed when operating with mice and rats.

    6Hz model: The 6-Hz corneal stimulation model, which was introduced in early fifties, has been recently rediscovered to test alternative approaches for drug-resistant seizures. Accordingly the ketogenic diet, which is known to be a valid treatment for refractory seizures, was found to be effective in counteracting seizures induced by the 6-Hz corneal stimulation. When compared with other models based on electrical stimulation, the 6-Hz paradigm is characterized by the induction of minimally convulsive or non-convulsive seizures with automatized behaviors, defined as “psychomotor seizures”. Ugo Basile ECT Unit performs the 6Hz model conveniently.

     

    57800 ECT Unit, complete with standard accessories
    57800-001 Pulse Generator
    57800-002 Set of Auricular Electrodes
    57800-320 Set of Felt Pads for Auricular Electrodes
    E-AU 041

    USB pen drive, including:

    57800-302 Instruction Manual

    Optional
    57800-003 Set of Corneal Electrodes
    57800-002 Bipolar Inverter
    57800-015 ECT Monitor, complete with connection cables
    • {module Bibliography on 57800}


Éléments similaires (par tag)

  • Rotamètre sans contact Rat souris
    The Rotometer is an original instrument from Ugo Basile, specifically designed for recording rotations in UNRESTRAINED MICE, by measuring the…

P.IVA, C.F. e n. Registro Imprese di Varese 02728350121 - n. REA VA-281472 - Cap. soc. i.v. € 165.000,00