Douleur et inflammation
Code: 37100

Boites de contention pour stimulation orofaciale "DURHAM"

Boites de contention pour rats au dessin original Ugo Basile pour une stimulation de la zone innervée par la branche mandibulaire du nerf trigéminal. Développé par le Dr. Paul Durham (Missouri State University), ces boites sont disponibles en deux tailles pour les rats. Moulées dans un plastique polymère rouge, elles sont opaques pour l'animal mais translucides pour l'opérateur. Elles limitent le stress de l'animal. Une ouverture appropriée a été procédé à la base de chaque boite permettant une stimulation de chaque côté de la gueule mais aussi des pattes arrière.
Compatible avec le Von Frey automatique et le test plantaire thermique Hargreaves.


These animal holders complete the scope of the infrared thermal stimulus of the Plantar Test, or the mechanical stimuus of the Dynamic Plantar Aesthesiometer, used for assessing hind paw withdrawal. This new invention allows the application of the same stimulus to the region innervated by the trigeminal nerve.

The Set includes two holders, form molded for testing specific size ranges of animals: the two sizes have been optimized for young adult rats as well as for bigger rats.

“Very nicely done - easy to use and it greatly facilitates consistent handling of animals” Dr. Ken Hargreaves, UT Texas

Informations supplémentaires

    Correlation thresholds in submandibular (trigeminal) region and hindpaw plantar surface A step forward toward multifactorial measurement of pain-related sensitivity in animal research
    Test orofacial nociception using a standard Plantar thermal or mechanical stimulator The new holders complete the scope of the thermal or mechanical stimulators used for assessing hind paw withdrawal

    deep-red color proprietary polymer

    Set of two rat holders
    Medium size for young adult rats 175 to 250 grams
    Large size: for rats 250 to 400 grams

    Weight: 0.4 Kg
    Shipping Weight: 1.0 Kg approx
    Packing dimensions: 39 x 27 x 21 cm


    The Durham Holders have distinct advantages which make them ideal as accessories to the classical Hargreaves test and they represent a step forward toward a multifactorial measurement of pain-related sensitivity in animal research.

    Quantification of localized hypersensitivity is common in the clinic, but not in animal experiments.

    The holders may appear similar to the classic Broome style animal holder; however, those restrainers are clunky, made of clear acrylic, and do not have stimulus apertures, so they could never be used for this stimulation.

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P.IVA, C.F. e n. Registro Imprese di Varese 02728350121 - n. REA VA-281472 - Cap. soc. i.v. € 165.000,00