Pain and inflammation

37100 - Durham Holders for Orofacial Stimulation

Durham Holders Durham Holders

The Durham Animal Holders are new rat holders for trigeminal stimulation, the newest accessory for use with the Plantar Test and Dynamic Plantar Aesthesiometer, manufactured by Ugo Basile.

These animal holders complete the scope of the infrared thermal stimulus of the Plantar Test, or the mechanical stimuus of the Dynamic Plantar Aesthesiometer, used for assessing hind paw withdrawal. This new invention allows the application of the same stimulus to the region innervated by the trigeminal nerve.

The Set includes two holders, form molded for testing specific size ranges of animals: the two sizes have been optimized for young adult rats as well as for bigger rats.

“Very nicely done - easy to use and it greatly facilitates consistent handling of animals” Dr. Ken Hargreaves, UT Texas

    FEATUREBENEFIT
    Correlation thresholds in submandibular (trigeminal) region and hindpaw plantar surface A step forward toward multifactorial measurement of pain-related sensitivity in animal research
    Test orofacial nociception using a standard Plantar thermal or mechanical stimulator The new holders complete the scope of the thermal or mechanical stimulators used for assessing hind paw withdrawal
       

    Material:
    deep-red color proprietary polymer

    Size:
    Set of two rat holders
    Medium size for young adult rats 175 to 250 grams
    Large size: for rats 250 to 400 grams

    Physical:
    Weight: 0.4 Kg
    Shipping Weight: 1.0 Kg approx
    Packing dimensions: 39 x 27 x 21 cm

     

    The Durham Holders have distinct advantages which make them ideal as accessories to the classical Hargreaves test and they represent a step forward toward a multifactorial measurement of pain-related sensitivity in animal research.

    Quantification of localized hypersensitivity is common in the clinic, but not in animal experiments.

    The holders may appear similar to the classic Broome style animal holder; however, those restrainers are clunky, made of clear acrylic, and do not have stimulus apertures, so they could never be used for this stimulation.

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