Motory Coordination, Grip, Strength, Activity

43000 - Rotometer

Rotometer Rotometer

The Rotometer is an original instrument from Ugo Basile, specifically designed for recording rotations in UNRESTRAINED MICE, by measuring the animal movements via a magnetic field detection system.

The greatest advantage to this instrument is that it measures free-moving rotational behaviour; no tether required. To quantify rotational behavior in a freely moving animal is a significant development: our model accomplishes precisely this task, using new and clever technology to count clockwise (CW) and counterclockwise (CCW) rotations in a circular open field.

Simply attach a tiny magnet (the size of a grain of rice) to the animal tail or nape and the Rotometer automatically tallies clockwise and counterclockwise rotations. For long term tests, the magnet can be injected.

The injectable magnets, encapsulated within a proven bio-compatible material, fit within syringes normally used for the injection of identification transponders. These small magnets are easy to inject in the animal’s nape and do not interfere with the animal behavior.

The mouse (or small rat) is placed on a 20cm diam. circular arena, enclosed in a clear Perspex cyinder, 25cm tall. Digital read-out shows accrued rotations. The Rotometer features Portable Memory Stick technology, USB interface, & software for connection to PC, all included in the standard package.

    FEATUREBENEFIT
    No harness, no jacket, no tether is required The animal is TRULY FREE AND UNRESTRAINED
    Extremely sensitive The magnet attached to tha animal is very small (2x15mm)
    The magnet can be attached anywhere on the animal Reduce the stress to the animal at its minimum
       
    General
    Commands via “soft keys”
    Starting via command key
    Read-out multifunction graphic display
    Print-Out By optional thermal MiniPrinter 57145
    Power Requirement Universal input 85-264 VAC, 50-60Hz, 40W max.
    Sound Level < 60 dB (A)
    Operating Temperature 18° to 40° C
    Connection to PC via USB connector type B
    Data Portability via USB flash drive, provided
    Physical
    Total Weight 3.5Kg
    Shipping Weight 7Kg approx.
    Dimensions 25(w)x37(d)x16(h)cm (without restrainer)
    Dimensions (restrainer) 20cm diam. x 25(h)cm  
    Packing Dimensions 68x34x28
    Warranty 43000 is covered by a 24-month warranty

    The Rotometer is widely used in research on motor assessment tests. Rotometer is also used in traumatic and acquired brain injury research and spinal cord injury research.

    There are several well-characterized causes for animals to exhibit rotational behavior:

    • Uneven/unilateral higher expression of levels of neurotransmitters (such as GABA or dopamine). Some brain tumors can cause aberrant expression levels to occur. Injury may also interfere with proper neurotransmitter expression, and/or cause some localized change in neurotransmitter expression
    • Developmental anomalies can also cause rotational behavior
    • Anxiety/stress may cause this aberrant behavior
    • Exposure to some drugs, or drug abuse, or withdrawal from some drugs, all may have rotational sequelae.
    • Physical lesions also can cause rotational behavior in an animal 

    To quantify rotational behavior in a freely moving animal is a significant development

     

    43000 ROTOMETER, standard package
    43000-001 Rotometer Main Unit
    35100-286 Perspex Animal Restrainer
    E-AU 041

    Memory Key

    43000-302 Instruction Manual

    52050-13CUB Data Acquisition Software Package

    OPTIONAL
    43000-321 Syringe kit, including 1 syringe and 2 injectable magnets
    43000-012 Magnets kit (including 10 magnets) 2x12 mm
    43000-052 Magnets kit (including 50 magnets) 2x12 mm
    43000-015 Magnets kit (including 10 magnets) 2x15 mm
    43000-055 Magnets kit (including 50 magnets) 2x15 mm
    57145 Thermal Mini Printer

     

     

     

     

     

     

    • M. Duckert: “Quantifizierung und motorisch-funktionelle Analyse von postlesional beobachtbaren Tyrosinhydroxylaseimmunreaktiven Neuronen im 6-OHDA-Parkinson-Modell der Maus” Dissertation, Rostock, 2012

    See Additional Bibliography

     

     

Media

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