Motory Coordination, Grip, Strength, Activity

47300 - Rodent Treadmill NG Featured

Rodent Treadmill Rodent Treadmill

Ugo Basile introduces an original TREADMILL for rats and mice. The same device is suitable for tests on either rats or mice. Shock option incorporated in all models.

The 47300 Treadmill is a compact and user-friendly device: test settings & monitoring are managed on the 4”3 touch-screen of the attached control unit.

Endurance, distance (absolute and relative) and speed are automatically measured and recorded.

Speed can be selected from 3 to 100m/min, in steps of 1m/min, in constant, accelerating, custom ramps modes.

Our model incorporates a shock grid at the back of the treadmill to deliver a mild electric shock, when an aversive stimulus is required. Shock can be preset from 0 to 2mA (in 0.1mA steps), with a frequency of 1, 2 or 3 Hz.

The running-lane assembly can be manually tilted from -25° to +25°, in steps of 5°. A special lane-assembly for tethered mice is also available in alternative to the standard model.

X-PAD Software to set the experiment and manage the results is included free of charge.

    SAME DEVICE TO TEST RATS & MICE

    MODES: constant, accelerating, custom ramps

    SLOPE: positive (uphill) or negative (downhill), from -25 to +25°, in 5° steps

    SPEED: from 3 to 100m/min, in steps of 1m/min amps

    SHOCK: from 0 to 2mA (in 0.1mA steps), included

    DETECTION: via incorporated electronic circuit automati­cally detects speed & absolute and relative distances

    CONTROLS: 4”3 touch-screen to set and monitor the test

    X-PAD SOFTWARE: brand new, user-friendly version, to set the experiment and manage the results

    General
    Commands 4”3 touch-screen (resistive)
    Read-out on the touch-screen
    Power Requirement Universal input 85-264 VAC, 50-60Hz, 40W max.
    Sound Level 80 dB ca., at maximum speed
    Operating Temperature 10° to 40° C
    Operation
    Speed adjustable in the range 3 to 100m/min, in steps of 1m/min
    Mode constant, ramp (accelerating), multi-step ramp (NEW!)
    Slope

    Manual tilting, positive (uphill) or negative (downhill)

    from -25° to +25°, in steps of 5°

    Shocker included
    Shock from 0 to 2mA (in 0.1mA steps), 1, 2 or 3Hz
    Start/Stop from the touch-screen
    Detection via incorporated electronic circuit
    Results Speed and distances (absolute and relative)
    Data Acquisition via dedicated X-PADsoftware, provided
    Data Portability by USB flash drive
    TTL Output Shock status (for each lane) and speed
    Data exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive
    Configurations exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive
    Physical
    Total Weight 47302 & 47303 : 22Kg – 47300 : 27Kg
    Shipping Weight 47302 & 47303 : 35Kg – 47300 : 40Kg approx.
    Dimensions 56(w)x67(d)x35(h)cm
    Packing Dimensions 47302 & 47303     : wooden crate, 77x65x63cm
    47300         : wooden crate, 82x71x57cm
    Warranty 47300 is covered by a 24-month warranty

    Exercise is a multifactorial activity that affects virtually every organ and tissue in the body. Not only does exercise contribute many health benefits, but lack of exercise is im-plicated in many chronic health problems.

    As evidence continues to accumulate concerning the impressive range of health benefits that exercise confers, biomedical researchers have increasingly become interested in conducting systematic studies of exercise to further define those benefits”.

    Fatigue is a common and frequently poorly-understood symptom in many diseases and disorders. New preclinical assays of fatigue may help to improve current understanding of fatigue-like behavior in rodents and many other exercise paradigms and study future treatment of fatigue.

    Treadmills are rolling belts (tapis-roulants) with presettable speed and adjustable uphill and downhill inclination (slope), enabling forced exercise training and accurate testing of fatigue in lab animals.

    Treadmill running has been used extensively over the past decades to study behavioral, physiological, biochemical, and, more recently, molecular responses to both acute exer-cise stress and chronic exercise training. Although investigators have used a wide variety of species (…) for treadmill running studies, they have used rodents in most of these studies.

    Treadmill running has the distinct advantage over other forms of exercise, including spontaneous wheel running and swimming, that the total amount of external work done by the rat can be easily calculated.

    Treadmill running may be construed as a form of forced exercise in which the animal does not have a choice of participating in the activity. Because of this, noxious stimuli (e.g., electric shock and bursts of high-pressure air) may be needed to motivate the animals to exercise” 

    (from Resource Book for the Design of Animal Exercise Protocols, APS, Feb 2006)

     

    47302 Rat Treadmill NG, complete with following accessories
    47300-001 Tapis-Roulant with touch-screen controller and shocker
    47300-002 3-Lane partition assembly for Rats, each lane 45x11x15(h)cm, with transparent cover
    E-AU 041

    USB pen drive, including:

    47300-302      Instruction Manual  

    X-PAD Software Package

    47303 Mouse Treadmill NG, complete with following accessories
    47300-001 Tapis-Roulant with touch-screen controller and shocker
    47300-003 6-Lane partition assembly for Mice, each lane 45x5.5x7(h)cm, with transparent cover
    E-AU 041

    USB pen drive, including:

    47300-302      Instruction Manual  

    X-PAD Software Package

    47303 Combo Package: Mouse & Rat Treadmill NG, complete with following accessories
    47300-001 Tapis-Roulant with touch-screen controller and shocker
    47300-003 6-Lane partition assembly for Mice, each lane 45x5.5x7(h)cm, with transparent cover
    E-AU 041

    USB pen drive, including:

    47300-302      Instruction Manual  

    X-PAD Software Package

    OPTIONAL
    47313 Mouse Treadmill NG, complete with standard accessories and in alternative to 47300-003:
    47300-013 6-lane assembly (each lane 45x5.5, height 15cm, without lid, for te­thered mice)

     

    47302

    Rat Treadmill NG: tapis-roulant with touch-screen controller and sho­cker. With 3-lane partition assembly 47300-002 (each lane 45x11x15(h) cm). Including shocker, manual til­ting (-45/+45), transparent cover. Complete with X-PAD software, USB output, USB flash drive

    47303

    Mouse Treadmill NG: as above, with 3-lane partition assembly 47300-002 (each lane 45x5.5x7(h)cm).

    X-PAD

    Dedicated Software Package

    E-WP 008

    Mains Cord

     

    Working with both rats and mice? You should consider the Combination Package 47300, including the main unit and both Mouse and Rat in­terchangeable lane-assemblies

     

    47300

    Combo-Package for Mouse & Rat

    47300-013

    Mouse 6-lane high-wall partition assembly (each lane 45x5.5, height 15cm, without lid, for tethered mice)

      

    See Additional Bibliography

    • American Physiological Society: “Resource Book for the Design of Animal Exercise Protocols” February 2006
    • O.J. Kemi et alia: “Intensity-Controlled Treadmill Running in Mice: Cardiacand Skeletal Muscle Hypertrophy” J. Appl. Physiol. 93: 1301-1309, 2002
    • X.Q. Wang & G.W. Wang: “Effects of Treadmill Exercise Intensity on Spatial Working Memory and Long-Term Memory in Rats” Life Sciences 149: 96-103, 2016
    • M. Shinozaki et alia: “Combined Treatment With Chondroitinase ABC and Treadmillrehabilitation for Chronic Severe Spinal Cord Injury in Adult Rats” Neuroscience Res 113: 37-47, 2016

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