Behaviour, Mazes, Tracking

40162 / 40163 - Elevated Zero-Maze

The Elevated Zero-Maze is sometimes preferred to the Elevated Plus-Maze, because it offers the animal a smoother transition from closed to open arms.

In the Elevated Plus-Maze, this transition implies that the animal actively turns to one of the two open arms, while in the Elevated Zero-Maze the transition occurs more spontaneously, as the animal simply keeps walking on the maze.

All Animal Mazes manufactured by Ugo Basile are designed to give optimal results with any Video-Tracking software. This is achieved by:

  • high-contrast colors: grey, white, black or the NEW Ugo Basile light-blue
  • non-reflective surface: reflections are a common source of error in animal tracking. Let’s avoid them!

All materials were selected to be sturdy and easy to clean, to construct reliable and durable mazes. Surface texture was selected for best rodent comfort (reasonably rough, “warm” surface).

The mouse Zero-Maze, has a diameter of 60cm, 5cmwide circular corridor , and 16cm high walls. In the rat model the diameter is 120cm, the corridor width is 10cm and the walls are 31cm high. Height from the floor is 60cm for either model. The Zero-Maze is supported by 4 metal legs, which make the device very stable. 

    FEATURE BENEFIT
    High-contrast colors Gives optimal results with any Video-Tracking software
    Non-reflecting surface Guarantees optimal camera view and no glare
    Ample color selection Available in grey (standard), blue, white, black, custom color
    Reasonably rough “warm” surface texture Selected for best rodent comfort, non-slippery
    Quality materials Reliable and durable mazes, easy to clean and store
    Physical 40162 Rat * 40163 Mouse
    Diameter 120cm 60cm
    Corridor Width 10cm   5cm
    Closed Corridor Walls 31cm 16cm
    Height (from the floor) 62cm 62cm
    Standard color Grey (RAL GR5001)
    Available colors Blue, white, black, color on request
    Weight 27Kg 8Kg
    Shipping Weight 35Kg 12Kg
    Packing Dimensions 135x135x30cm 105x105x20cm
    Warranty 40162/3 is covered by a 24-month warranty
    * NOTE: in order to avoid dead-spaces in the camera view, the rat model requires the integrated use of 2 videocameras

     

     

    Elevated zero maze is a modification of the elevated plus maze model of anxiety in rodents, which incorporates both traditional and novel ethological measures in the analysis of drug effects.

    The elevated zero-maze constitutes a modification in both design and procedure which aims to improve upon the traditional model by increasing the sensitivity to, and facilitating interpretation of, drug action.

    The novel design comprises an elevated annular platform with two opposite, enclosed quadrants and two open quadrants, addresses one potentially problematic issue inherent in the plus-maze design, i.e., the unavoidable ambiguity associated with time spent on the central square, removing any ambiguity in the interpretation and allowing uninterrupted exploration.

    The Zero-Maze design, combined with a detailed behavioral analysis, represents a reliable animal model of anxiety.

    40162 Zero-Maze for Rats
    40163 Zero-Maze for Mice
      OPTIONAL
    60000 ANY-maze Software
    41700-040 B/W USB Camera, including day&night 2.7-13.5mm varifocal lens, 5m USB cable and ceiling support

     

     

    See Additional Bibliography

    • J.K. Shepherd et alia: “Behavioral and Pharmacological Characterisation of the elevated “Zero-Maze” as an Animal Model of Anxiety” Psychopharmacology 116: 56-64, 1994
    • K.B. Troelsen et alia: “Chronic treatment with duloxetine is necessary for an anxiolytic-like response in the mouse zero maze: the role of the serotonin transporter” Psychopharmacology 181(4): 741-750, 2005

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