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57800 - ECT Unit
The ECT apparatus (Electro Convulsive Therapy) is specially designed for neurochemical and neuropharmacological research. A constant current output is used, which ensures reproducible results and accurate determination of the EC threshold while also pinpointing any variations in the threshold brought about by drugs having a specific action on the cortex and sub-cortical regions. The shock parameters have been selected after consulting the most recent literature, to supply the most suitable range when operating with mice and rats.
The ECT apparatus (Electro Convulsive Therapy) is specially designed for neurochemical and neuropharmacological research. A constant current output is used, which ensures reproducible results and accurate determination of the EC threshold while also pinpointing any variations in the threshold brought about by drugs having a specific action on the cortex and sub-cortical regions. The shock parameters have been selected after consulting the most recent literature, to supply the most suitable range when operating with mice and rats.
Consistent reproducible current levels are produced by feedback circuitry that adjust for variance in impedance of the contact from animal to animal.
The impedance to the animal can be pre-measured and displayed, and a warning signal flashes if the impedance is too great to deliver the desired current level.
The standard auricular electrodes supplied (see main picture) allow a single operator to deliver shock to a number of animals in a short time.
The special output circuit enables any type of electrode to be used.
Features and Benefits
Specifications
Accessories
Bibliography
| FEATURE |
BENEFIT |
| Optional analogue output |
Can be connected to oscilloscope |
| Any type of electrode can be used |
Allows for virtually any procedure |
| Feedback circuitry |
Compensates for impedance variability due to animal-electrode contact |
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| Rectangular Positive Pulse: |
by H.V. transformer |
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Pulse Voltage: |
max. 2.5 KV |
| Constant Current: |
by feedback network |
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Current Range: |
10-99 mA in 1 mA steps ±2% |
| Pulse Rise&Fall Time: |
20 µs |
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Output Resistance: |
min 0 Ohm - max. 25 KOhm (at max. current) |
| Pulse Width (ms): |
0.1 to 0.9 in 0.1ms steps ±1% |
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KOhm Display: |
0-199 KOhm 1KOhm resolution |
| Frequency (pulses/s): |
1-299 in 1 pulse/s steps ±1% |
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Power Requirements: |
115/230 V - 50/60 Hz - 70 VA max |
| Shock Duration |
0.1 to 9.9 in 0.1s steps ±1% |
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| 57800-003: |
Set of Corneal Electrodes |
| 57800-320: |
Set of 4 Felt Pads for Auricular Electrodes |
| Bipolar Inverter57800-010: |
An optional Biphasic Unit may be placed between the animal and the Electroconvulsive Device to invert every other pulse. Maximum frequency in this case becomes 100 Hz.
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· A.L. Hartman et alia: “Efficacy of the Ketogenic Diet in the 6-Hz Seizure Test” Epilepsia 49(2): 334-339, 2008
· J.E. Ploski et alia: "Electroconvulsive Seizure-Induced Gene Expression Profile of the Hippocampus Dentate Gyrus Granule Cell Layer" J.Neurochemistry 99 (4): 1122-1132, 2006
· K. Takahashi et alia: "Expression of Ndrg2 in the Rat Frontal Cortex After Antidepressant and Electroconvulsive Treatment" Int. J. Neuropsy-chopharm. 8: 381-389, 2005
